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Axsome Therapeutics vs Supernus Pharmaceuticals

Axsome Therapeutics and Supernus Pharmaceuticals are similar in size: $638m and $719m of revenue in their latest fiscal years. Axsome Therapeutics grew faster (65.5% against 8.6%). Supernus Pharmaceuticals kept more of each dollar of sales as profit: a net margin of -5.4% against -28.7%. Supernus Pharmaceuticals carries less debt relative to equity (0.0% against 212.6%).

Latest fiscal yearAxsome TherapeuticsAXSM, 2025Supernus PharmaceuticalsSUPN, 2025
Revenue $638m $719m
Revenue growth 65.5% 8.6%
Net income −$183m −$38.5m
Operating margin -26.1% -8.7%
Net margin -28.7% -5.4%
Return on equity — -3.7%
Free cash flow −$93.9m $46.0m
Cash $323m $128m
Total debt $188m $0
Debt to equity 212.6% 0.0%
Dividend per share — —
Dividend yield — —
Share buybacks — —
Employees — 778
Market value $7.38bn $1.65bn
Price vs our value range — Below our value range
Moat score — 69 (Moderate)
Insider trades, 12 months 0 buys, 33 sales 0 buys, 20 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

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Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.