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Mesoblast vs Arcus Biosciences

Arcus Biosciences is the larger business, with $247m of revenue in fiscal 2025 against $120m for Mesoblast (2.1 times as much). Mesoblast grew faster (599.2% against -4.3%). Mesoblast kept more of each dollar of sales as profit: a net margin of -47.8% against -142.9%. Arcus Biosciences carries less debt relative to equity (15.8% against 22.8%).

Latest fiscal yearMesoblastMESO, 2026Arcus BiosciencesRCUS, 2025
Revenue $120m $247m
Revenue growth 599.2% -4.3%
Net income −$57.5m −$353m
Operating margin — -156.3%
Net margin -47.8% -142.9%
Return on equity -9.9% -63.3%
Free cash flow −$44.7m −$484m
Cash $103m $222m
Total debt $130m $100m
Debt to equity 22.8% 15.8%
Dividend per share — —
Dividend yield — —
Share buybacks — —
Employees — 601
Market value $1.91bn $2.39bn
Price vs our value range — —
Moat score — 10 (Weak)
Insider trades, 12 months 24 buys, 0 sales 0 buys, 0 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

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Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.