Anaptysbio, Inc: which funds bought and sold

Institutions that bought and sold Anaptysbio shares in Q2 2026, from the holdings they reported to the SEC on Form 13F for March 31, 2026 and June 30, 2026.

Between March 31, 2026 and June 30, 2026, 113 institutions that filed 13F reports for both quarters added to or opened positions in Anaptysbio, and 101 cut or closed them. Together they added a net 1.9M shares, +6.7% on what they held at the start of the quarter. Active managers and hedge funds on our list were net buyers of 505K shares (+3.4%); index fund managers were net buyers of 672K shares (+13.1%). 42 opened a new position and 36 sold out entirely.

Bought, Q2 2026 113 institutions, 42 of them new holders Sold, Q2 2026 101 institutions, 36 of them sold out

Net change, all compared +1.9M shares (+6.7%)

Net change, active managers +505K shares (+3.4%), 23 bought, 24 sold

Buyers versus sellers

institutions compared, 243

113 bought 29 101 sold

Active managers and hedge funds 23 bought · 24 sold · +505K

Index fund managers 9 bought · 2 sold · +672K

Other institutions 81 bought · 75 sold · +713K

Biggest buyers

by change in shares held

Biggest buyers
Institution	Change in shares	Shares June 30, 2026	Value
Woodline Partners LP Hedge fund	+373K +108.3%	717K	$48.4M
Millennium Management LLC Hedge fund	+332K +69.8%	807K	$54.5M
State Street Corp Index funds	+294K +29.6%	1.3M	$86.8M
Apis Capital Advisors, LLC	+259K +108.8%	497K	$33.5M
First Trust Advisors LP	+259K New position	259K	$17.5M
Goldman Sachs Group Inc	+251K +75.5%	584K	$39.4M
Sofinnova Investments, Inc.	+245K +98.8%	494K	$33.3M
Empowered Funds, LLC	+206K New position	206K	$13.9M
Dimensional Fund Advisors LP	+185K New position	185K	$12.5M
Greenhaven Road Investment Management, L.P.	+171K New position	171K	$11.5M
Blackrock, Inc. Index funds	+163K +9.7%	1.8M	$124M
Citadel Advisors LLC Hedge fund	+161K +68.9%	394K	$26.6M
Geode Capital Management, LLC Index funds	+118K +22.6%	638K	$43.1M
Mackenzie Financial Corp	+117K +347.7%	151K	$10.2M
Nuveen, LLC	+105K +33.1%	421K	$28.4M
HSBC Holdings PLC	+91K +72.6%	217K	$14.9M
DZ Bank AG Deutsche Zentral Genossenschafts Bank, Frankfurt Am Main	+84K New position	84K	$5.7M
Invesco Ltd.	+81K +66.8%	202K	$13.6M
Irenic Capital Management LP Hedge fund	+70K New position	70K	$4.8M
Jpmorgan Chase & Co	+69K +589.0%	80K	$5.3M

Biggest buyers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Woodline Partners LP Hedge fund	+373K +108.3%	717K	$48.4M
Millennium Management LLC Hedge fund	+332K +69.8%	807K	$54.5M
Citadel Advisors LLC Hedge fund	+161K +68.9%	394K	$26.6M
Irenic Capital Management LP Hedge fund	+70K New position	70K	$4.8M
Victory Capital Management Inc Active manager	+61K +56.4%	169K	$11.4M
Squarepoint Ops LLC Hedge fund	+57K +21.2%	324K	$21.9M
Eversept Partners, LP Hedge fund	+43K +158.3%	70K	$4.7M
Franklin Resources Inc Active manager	+41K +62.5%	107K	$7.2M
Capital Fund Management S.A. Hedge fund	+39K New position	39K	$2.6M
683 Capital Management, LLC Hedge fund	+35K +5.6%	660K	$44.6M

Biggest sellers

by change in shares held

Biggest sellers
Institution	Change in shares	Shares June 30, 2026	Value
Morgan Stanley	−737K −74.1%	257K	$17.4M
Synergy Asset Management, LLC	−317K Sold out	0	—
FMR LLC Active manager	−232K −49.1%	241K	$16.2M
Two Sigma Investments, LP Hedge fund	−202K −43.5%	263K	$17.8M
Affinity Asset Advisors, LLC	−114K −12.1%	826K	$55.8M
BNP Paribas Financial Markets	−89K −91.8%	7,967	$537,772
Jane Street Group, LLC	−86K Sold out	0	—
Bank Of America Corp	−83K −16.6%	418K	$28.2M
Fisher Asset Management, LLC Active manager	−57K Sold out	0	—
Point72 Asset Management, L.P. Hedge fund	−55K Sold out	0	—
Highmark Wealth Management LLC	−54K −57.8%	40K	$2.7M
Trexquant Investment LP Hedge fund	−50K −58.4%	35K	$2.4M
Penserra Capital Management LLC	−43K Sold out	0	—
HRT Financial LP	−41K Sold out	0	—
D. E. Shaw & Co., Inc. Hedge fund	−40K −6.8%	540K	$36.4M
Palo Alto Investors LP	−35K −5.4%	603K	$40.7M
Virtu Financial LLC	−33K Sold out	0	—
Renaissance Technologies LLC Hedge fund	−33K −35.9%	58K	$3.9M
Susquehanna Portfolio Strategies, LLC	−31K −86.4%	4,882	$329,535
Xtx Topco Ltd	−29K −57.6%	21K	$1.4M

Biggest sellers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
FMR LLC Active manager	−232K −49.1%	241K	$16.2M
Two Sigma Investments, LP Hedge fund	−202K −43.5%	263K	$17.8M
Fisher Asset Management, LLC Active manager	−57K Sold out	0	—
Point72 Asset Management, L.P. Hedge fund	−55K Sold out	0	—
Trexquant Investment LP Hedge fund	−50K −58.4%	35K	$2.4M
D. E. Shaw & Co., Inc. Hedge fund	−40K −6.8%	540K	$36.4M
Renaissance Technologies LLC Hedge fund	−33K −35.9%	58K	$3.9M
Engineers Gate Manager LP Hedge fund	−28K Sold out	0	—
Qube Research & Technologies Ltd Hedge fund	−26K −10.2%	229K	$15.4M
Marshall Wace, LLP Hedge fund	−24K −35.6%	44K	$3M

New positions

largest by value

Institution	Shares	Value June 30, 2026
First Trust Advisors LP	259K	$17.5M
Empowered Funds, LLC	206K	$13.9M
Dimensional Fund Advisors LP	185K	$12.5M
Greenhaven Road Investment Management, L.P.	171K	$11.5M
DZ Bank AG Deutsche Zentral Genossenschafts Bank, Frankfurt Am Main	84K	$5.7M
Irenic Capital Management LPHedge fund	70K	$4.8M
Capital Fund Management S.A.Hedge fund	39K	$2.6M
Atom Investors LP	34K	$2.3M
Voleon Capital Management LPHedge fund	31K	$2.1M
Aquatic Capital Management LLC	31K	$2.1M

Sold out

largest by value

Institution	Shares	Value March 31, 2026
Synergy Asset Management, LLC	317K	$17.6M
Jane Street Group, LLC	86K	$4.8M
Fisher Asset Management, LLCActive manager	57K	$3.1M
Point72 Asset Management, L.P.Hedge fund	55K	$3.1M
Penserra Capital Management LLC	43K	$2.4M
HRT Financial LP	41K	$2.2M
Virtu Financial LLC	33K	$1.8M
Engineers Gate Manager LPHedge fund	28K	$1.5M
Susquehanna International Group, LLP	27K	$1.5M
Headlands Technologies LLC	25K	$1.4M

Who holds the shares

13F holdings at June 30, 2026

Institutions reporting: 210
Ten largest holders: 56.7%
Index fund managers: 19.3%
Active managers and hedge funds: 50.8%

Buying and selling by type of institution, March 31, 2026 to June 30, 2026
Type	Bought	Sold	New	Sold out	Net change in shares	Net %
Active managers and hedge funds	23	24	6	9	+505K	+3.4%
Index fund managers	9	2	0	0	+672K	+13.1%
Other institutions	81	75	36	27	+713K	+8.6%

Active managers and hedge funds: a list we maintain of about 400 well-known stock-picking firms and hedge funds, matched by SEC registration number (CIK) and checked against the filer names each quarter. Index fund managers: the large index houses, such as BlackRock, Vanguard, State Street, Geode and Northern Trust. Every other filer (banks, brokers, wealth managers, pension funds, insurers and firms not on the list) counts as another institution. A firm that files under several SEC registrations appears once for each.

What these filings can and cannot tell you

Form 13F lists the long positions in US-listed shares held by investment managers with more than $100 million in such holdings. Managers file it up to 45 days after each quarter ends, so this page shows what funds held at the end of each quarter, not what they are doing now: a position may have changed since. Short positions, most derivatives and smaller managers are not included, and a cut can mean a fund lost clients or rebalanced rather than a view on Anaptysbio.

Only managers that filed a holdings report for both quarters are compared (243 here). 9 other holders are left out: first-time or late filers, firms that changed their SEC registration, and filings that withheld positions under confidential treatment, any of which would otherwise look like a new position or a sale. Figures are as reported by each manager in the SEC's quarterly 13F data sets; option positions are excluded.

← Back to Anaptysbio, Inc · Insiders · Politicians