Caribou Biosciences, Inc.: which funds bought and sold

Institutions that bought and sold Caribou Biosciences shares in Q2 2026, from the holdings they reported to the SEC on Form 13F for March 31, 2026 and June 30, 2026.

Between March 31, 2026 and June 30, 2026, 70 institutions that filed 13F reports for both quarters added to or opened positions in Caribou Biosciences, and 45 cut or closed them. Together they added a net 10.9M shares, +28.8% on what they held at the start of the quarter. Active managers and hedge funds on our list were net sellers of 1.7M shares (−12.2%); index fund managers were net buyers of 10.2M shares (+117.1%). 23 opened a new position and 22 sold out entirely.

Bought, Q2 2026 70 institutions, 23 of them new holders Sold, Q2 2026 45 institutions, 22 of them sold out

Net change, all compared +10.9M shares (+28.8%)

Net change, active managers −1.7M shares (−12.2%), 12 bought, 9 sold

Buyers versus sellers

institutions compared, 159

70 bought 44 45 sold

Active managers and hedge funds 12 bought · 9 sold · −1.7M

Index fund managers 10 bought · 1 sold · +10.2M

Other institutions 48 bought · 35 sold · +2.4M

Biggest buyers

by change in shares held

Biggest buyers
Institution	Change in shares	Shares June 30, 2026	Value
Blackrock, Inc. Index funds	+5.7M +264.7%	7.8M	$13.8M
Mackenzie Financial Corp	+2.7M +287.2%	3.7M	$6.4M
Geode Capital Management, LLC Index funds	+1.4M +133.3%	2.4M	$4.2M
State Street Corp Index funds	+1.2M +285.8%	1.6M	$2.9M
Acadian Asset Management LLC Active manager	+849K +91.8%	1.8M	$3.1M
Vanguard Portfolio Management LLC Index funds	+614K New position	614K	$1.1M
Northern Trust Corp Index funds	+495K +227.4%	713K	$1.3M
Vanguard Capital Management LLC Index funds	+441K +11.7%	4.2M	$7.4M
Qube Research & Technologies Ltd Hedge fund	+369K +208.9%	546K	$960,529
Dimensional Fund Advisors LP	+302K +44.9%	975K	$1.7M
UBS Group AG	+258K +99.6%	517K	$910,573
Cambridge Investment Research Advisors, Inc.	+218K +39.8%	765K	$1.3M
Invesco Ltd.	+218K +260.6%	301K	$529,966
Charles Schwab Investment Management Inc Index funds	+216K +38.6%	776K	$1.4M
Bank Of New York Mellon Corp	+210K +1678.9%	223K	$391,706
Renaissance Technologies LLC Hedge fund	+183K +7.1%	2.8M	$4.9M
Man Group PLC Hedge fund	+163K +210.9%	240K	$422,516
Susquehanna Portfolio Strategies, LLC	+159K New position	159K	$279,131
Nuveen, LLC	+124K New position	124K	$217,388
Graham Capital Management, L.P. Hedge fund	+117K +302.3%	156K	$274,409

Biggest buyers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Acadian Asset Management LLC Active manager	+849K +91.8%	1.8M	$3.1M
Qube Research & Technologies Ltd Hedge fund	+369K +208.9%	546K	$960,529
Renaissance Technologies LLC Hedge fund	+183K +7.1%	2.8M	$4.9M
Man Group PLC Hedge fund	+163K +210.9%	240K	$422,516
Graham Capital Management, L.P. Hedge fund	+117K +302.3%	156K	$274,409
Jacobs Levy Equity Management, Inc Active manager	+52K +14.5%	411K	$723,323
Quadrature Capital Ltd Hedge fund	+49K +124.9%	89K	$156,603
Alliancebernstein L.P. Active manager	+37K New position	37K	$70,452
American Century Companies Inc Active manager	+28K +25.0%	141K	$247,421
Intech Investment Management LLC Active manager	+20K New position	20K	$34,971

Biggest sellers

by change in shares held

Biggest sellers
Institution	Change in shares	Shares June 30, 2026	Value
Aberdeen Group PLC	−1.2M Sold out	0	—
Millennium Management LLC Hedge fund	−1.0M −95.2%	51K	$90,061
Marshall Wace, LLP Hedge fund	−830K −68.8%	376K	$661,205
Two Sigma Investments, LP Hedge fund	−714K −40.6%	1.0M	$1.8M
Susquehanna International Group, LLP	−671K −80.2%	165K	$291,129
Pfm Health Sciences, LP Hedge fund	−603K −63.0%	355K	$624,249
Point72 Asset Management, L.P. Hedge fund	−172K −91.6%	16K	$27,753
Morgan Stanley	−124K −50.5%	121K	$213,523
Omers Administration Corp	−120K Sold out	0	—
Citadel Advisors LLC Hedge fund	−119K −74.6%	40K	$71,130
HRT Financial LP	−79K Sold out	0	—
Brevan Howard Capital Management LP Hedge fund	−65K Sold out	0	—
Xtx Topco Ltd	−54K −16.8%	269K	$473,716
Goldman Sachs Group Inc	−54K −14.3%	323K	$568,260
Jefferies Financial Group Inc.	−33K Sold out	0	—
Diametric Capital, LP	−33K Sold out	0	—
Catalyst Funds Management Pty Ltd	−32K Sold out	0	—
Envestnet Asset Management Inc	−31K Sold out	0	—
Schonfeld Strategic Advisors LLC Hedge fund	−24K Sold out	0	—
Nine Masts Capital Ltd	−21K Sold out	0	—

Biggest sellers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Millennium Management LLC Hedge fund	−1.0M −95.2%	51K	$90,061
Marshall Wace, LLP Hedge fund	−830K −68.8%	376K	$661,205
Two Sigma Investments, LP Hedge fund	−714K −40.6%	1.0M	$1.8M
Pfm Health Sciences, LP Hedge fund	−603K −63.0%	355K	$624,249
Point72 Asset Management, L.P. Hedge fund	−172K −91.6%	16K	$27,753
Citadel Advisors LLC Hedge fund	−119K −74.6%	40K	$71,130
Brevan Howard Capital Management LP Hedge fund	−65K Sold out	0	—
Schonfeld Strategic Advisors LLC Hedge fund	−24K Sold out	0	—
AQR Capital Management LLC Hedge fund	−16K Sold out	0	—

New positions

largest by value

Institution	Shares	Value June 30, 2026
Vanguard Portfolio Management LLCIndex funds	614K	$1.1M
Susquehanna Portfolio Strategies, LLC	159K	$279,131
Nuveen, LLC	124K	$217,388
Deutsche Bank Ag\	90K	$157,652
Rhumbline AdvisersIndex funds	69K	$120,681
Alliancebernstein L.P.Active manager	37K	$70,452
New York State Common Retirement Fund	35K	$62,304
Police & Firemen'S Retirement System Of New Jersey	27K	$47,668
Spark Investment Management LLC	24K	$41,536
Manufacturers Life Insurance Company, The	23K	$41,297

Sold out

largest by value

Institution	Shares	Value March 31, 2026
Aberdeen Group PLC	1.2M	$2.3M
Omers Administration Corp	120K	$228,380
HRT Financial LP	79K	$150,000
Brevan Howard Capital Management LPHedge fund	65K	$123,618
Jefferies Financial Group Inc.	33K	$63,198
Diametric Capital, LP	33K	$62,306
Catalyst Funds Management Pty Ltd	32K	$61,180
Envestnet Asset Management Inc	31K	$58,113
Schonfeld Strategic Advisors LLCHedge fund	24K	$45,540
Nine Masts Capital Ltd	21K	$39,163

Who holds the shares

13F holdings at June 30, 2026

Institutions reporting: 137
Ten largest holders: 67.4%
Index fund managers: 38.7%
Active managers and hedge funds: 24.8%

Buying and selling by type of institution, March 31, 2026 to June 30, 2026
Type	Bought	Sold	New	Sold out	Net change in shares	Net %
Active managers and hedge funds	12	9	3	3	−1.7M	−12.2%
Index fund managers	10	1	3	0	+10.2M	+117.1%
Other institutions	48	35	17	19	+2.4M	+15.8%

Active managers and hedge funds: a list we maintain of about 400 well-known stock-picking firms and hedge funds, matched by SEC registration number (CIK) and checked against the filer names each quarter. Index fund managers: the large index houses, such as BlackRock, Vanguard, State Street, Geode and Northern Trust. Every other filer (banks, brokers, wealth managers, pension funds, insurers and firms not on the list) counts as another institution. A firm that files under several SEC registrations appears once for each.

What these filings can and cannot tell you

Form 13F lists the long positions in US-listed shares held by investment managers with more than $100 million in such holdings. Managers file it up to 45 days after each quarter ends, so this page shows what funds held at the end of each quarter, not what they are doing now: a position may have changed since. Short positions, most derivatives and smaller managers are not included, and a cut can mean a fund lost clients or rebalanced rather than a view on Caribou Biosciences.

Only managers that filed a holdings report for both quarters are compared (159 here). 1 other holder is left out: first-time or late filers, firms that changed their SEC registration, and filings that withheld positions under confidential treatment, any of which would otherwise look like a new position or a sale. Figures are as reported by each manager in the SEC's quarterly 13F data sets; option positions are excluded.

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