Castle Biosciences Inc: which funds bought and sold

Institutions that bought and sold Castle Biosciences shares in Q2 2026, from the holdings they reported to the SEC on Form 13F for March 31, 2026 and June 30, 2026.

Between March 31, 2026 and June 30, 2026, 99 institutions that filed 13F reports for both quarters added to or opened positions in Castle Biosciences, and 86 cut or closed them. Together they sold a net 327K shares, −1.2% on what they held at the start of the quarter. Active managers and hedge funds on our list were net buyers of 80K shares (+1.0%); index fund managers were net buyers of 492K shares (+6.8%). 20 opened a new position and 30 sold out entirely.

Bought, Q2 2026 99 institutions, 20 of them new holders Sold, Q2 2026 86 institutions, 30 of them sold out

Net change, all compared −327K shares (−1.2%)

Net change, active managers +80K shares (+1.0%), 20 bought, 18 sold

Buyers versus sellers

institutions compared, 202

99 bought 17 86 sold

Active managers and hedge funds 20 bought · 18 sold · +80K

Index fund managers 8 bought · 1 sold · +492K

Other institutions 71 bought · 67 sold · −899K

Biggest buyers

by change in shares held

Biggest buyers
Institution	Change in shares	Shares June 30, 2026	Value
Mackenzie Financial Corp	+719K +970.7%	794K	$18.9M
Jefferies Financial Group Inc.	+647K New position	647K	$15.4M
Acadian Asset Management LLC Active manager	+434K +89.6%	919K	$21.9M
Point72 Asset Management, L.P. Hedge fund	+357K New position	357K	$8.5M
Kennedy Capital Management LLC Active manager	+348K New position	348K	$8.3M
Blackrock, Inc. Index funds	+309K +10.4%	3.3M	$78.5M
First Trust Advisors LP	+145K New position	145K	$3.5M
Citadel Advisors LLC Hedge fund	+144K +119.3%	265K	$6.3M
Allspring Global Investments Holdings, LLC	+132K +82.0%	292K	$7M
AQR Capital Management LLC Hedge fund	+102K +156.7%	167K	$4M
HRT Financial LP	+100K +630.6%	116K	$2.8M
Panagora Asset Management Inc Active manager	+79K +35.4%	301K	$7.2M
Trexquant Investment LP Hedge fund	+76K +58.0%	206K	$4.9M
Geode Capital Management, LLC Index funds	+68K +9.3%	796K	$19M
Arrowstreet Capital, Limited Partnership Hedge fund	+66K +241.7%	93K	$2.2M
Man Group PLC Hedge fund	+62K +130.7%	109K	$2.6M
State Street Corp Index funds	+53K +6.9%	822K	$19.6M
Vanguard Capital Management LLC Index funds	+49K +4.2%	1.2M	$29.3M
UBS Group AG	+40K +81.8%	89K	$2.1M
Sei Investments Co	+39K +112.4%	74K	$1.8M

Biggest buyers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Acadian Asset Management LLC Active manager	+434K +89.6%	919K	$21.9M
Point72 Asset Management, L.P. Hedge fund	+357K New position	357K	$8.5M
Kennedy Capital Management LLC Active manager	+348K New position	348K	$8.3M
Citadel Advisors LLC Hedge fund	+144K +119.3%	265K	$6.3M
AQR Capital Management LLC Hedge fund	+102K +156.7%	167K	$4M
Panagora Asset Management Inc Active manager	+79K +35.4%	301K	$7.2M
Trexquant Investment LP Hedge fund	+76K +58.0%	206K	$4.9M
Arrowstreet Capital, Limited Partnership Hedge fund	+66K +241.7%	93K	$2.2M
Man Group PLC Hedge fund	+62K +130.7%	109K	$2.6M
Algert Global LLC Hedge fund	+36K +102.7%	70K	$1.7M

Biggest sellers

by change in shares held

Biggest sellers
Institution	Change in shares	Shares June 30, 2026	Value
Portolan Capital Management, LLC	−1.0M −75.6%	329K	$7.8M
Eventide Asset Management, LLC	−386K Sold out	0	—
Palisade Capital Management, LP Active manager	−304K −56.7%	232K	$5.5M
Schroder Investment Management Group Active manager	−299K Sold out	0	—
Nuveen, LLC	−290K −55.6%	232K	$5.5M
Dimensional Fund Advisors LP	−249K −23.9%	791K	$18.9M
SG Americas Securities, LLC	−245K Sold out	0	—
Tudor Investment Corp Et Al Hedge fund	−209K −93.5%	14K	$344,919
Wasatch Advisors LP Active manager	−176K −38.6%	279K	$6.7M
Renaissance Technologies LLC Hedge fund	−162K −30.3%	371K	$8.9M
Two Sigma Investments, LP Hedge fund	−148K −59.7%	100K	$2.4M
Millennium Management LLC Hedge fund	−148K −41.9%	205K	$4.9M
Campbell & Co Investment Adviser LLC	−132K −88.9%	16K	$392,953
Summit Partners Public Asset Management, LLC	−116K −12.3%	825K	$19.7M
Morgan Stanley	−99K −23.1%	330K	$7.9M
D. E. Shaw & Co., Inc. Hedge fund	−99K −46.8%	113K	$2.7M
BNP Paribas Financial Markets	−53K −43.0%	70K	$1.7M
Formula Growth Ltd	−46K Sold out	0	—
Aigh Capital Management LLC	−46K −7.7%	545K	$13M
Connor, Clark & Lunn Investment Management Ltd.	−45K −12.0%	332K	$7.9M

Biggest sellers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Palisade Capital Management, LP Active manager	−304K −56.7%	232K	$5.5M
Schroder Investment Management Group Active manager	−299K Sold out	0	—
Tudor Investment Corp Et Al Hedge fund	−209K −93.5%	14K	$344,919
Wasatch Advisors LP Active manager	−176K −38.6%	279K	$6.7M
Renaissance Technologies LLC Hedge fund	−162K −30.3%	371K	$8.9M
Two Sigma Investments, LP Hedge fund	−148K −59.7%	100K	$2.4M
Millennium Management LLC Hedge fund	−148K −41.9%	205K	$4.9M
D. E. Shaw & Co., Inc. Hedge fund	−99K −46.8%	113K	$2.7M
Bridgeway Capital Management, LLC Active manager	−34K −13.3%	221K	$5.3M
Exoduspoint Capital Management, LP Hedge fund	−33K Sold out	0	—

New positions

largest by value

Institution	Shares	Value June 30, 2026
Jefferies Financial Group Inc.	647K	$15.4M
Point72 Asset Management, L.P.Hedge fund	357K	$8.5M
Kennedy Capital Management LLCActive manager	348K	$8.3M
First Trust Advisors LP	145K	$3.5M
Tidal Investments LLC	22K	$529,136
Counterpoint Mutual Funds LLC	17K	$393,764
Diversify Advisory Services, LLC	16K	$389,378
Quadrature Capital LtdHedge fund	10K	$242,674
Allstate Corp	9,642	$229,962
Entrypoint Capital, LLC	8,942	$213,267

Sold out

largest by value

Institution	Shares	Value March 31, 2026
Eventide Asset Management, LLC	386K	$9.5M
Schroder Investment Management GroupActive manager	299K	$7M
SG Americas Securities, LLC	245K	$6M
Formula Growth Ltd	46K	$1.1M
Nomura Holdings Inc	36K	$877,613
Exoduspoint Capital Management, LPHedge fund	33K	$800,526
Corient Private Wealth LP	32K	$782,410
Fox Run Management, L.L.C.	26K	$618,117
Magnetar Financial LLCHedge fund	23K	$572,800
Brevan Howard Capital Management LPHedge fund	19K	$455,648

Who holds the shares

13F holdings at June 30, 2026

Institutions reporting: 176
Ten largest holders: 51.3%
Index fund managers: 28.4%
Active managers and hedge funds: 29.7%

Buying and selling by type of institution, March 31, 2026 to June 30, 2026
Type	Bought	Sold	New	Sold out	Net change in shares	Net %
Active managers and hedge funds	20	18	5	5	+80K	+1.0%
Index fund managers	8	1	0	0	+492K	+6.8%
Other institutions	71	67	15	25	−899K	−7.3%

Active managers and hedge funds: a list we maintain of about 400 well-known stock-picking firms and hedge funds, matched by SEC registration number (CIK) and checked against the filer names each quarter. Index fund managers: the large index houses, such as BlackRock, Vanguard, State Street, Geode and Northern Trust. Every other filer (banks, brokers, wealth managers, pension funds, insurers and firms not on the list) counts as another institution. A firm that files under several SEC registrations appears once for each.

What these filings can and cannot tell you

Form 13F lists the long positions in US-listed shares held by investment managers with more than $100 million in such holdings. Managers file it up to 45 days after each quarter ends, so this page shows what funds held at the end of each quarter, not what they are doing now: a position may have changed since. Short positions, most derivatives and smaller managers are not included, and a cut can mean a fund lost clients or rebalanced rather than a view on Castle Biosciences.

Only managers that filed a holdings report for both quarters are compared (202 here). 8 other holders are left out: first-time or late filers, firms that changed their SEC registration, and filings that withheld positions under confidential treatment, any of which would otherwise look like a new position or a sale. Figures are as reported by each manager in the SEC's quarterly 13F data sets; option positions are excluded.

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