Structure Therapeutics Inc.: which funds bought and sold

Institutions that bought and sold Structure Therapeutics shares in Q2 2026, from the holdings they reported to the SEC on Form 13F for March 31, 2026 and June 30, 2026.

Between March 31, 2026 and June 30, 2026, 104 institutions that filed 13F reports for both quarters added to or opened positions in Structure Therapeutics, and 80 cut or closed them. Together they added a net 787K shares, +1.3% on what they held at the start of the quarter. Active managers and hedge funds on our list were net buyers of 405K shares (+1.0%); index fund managers were net buyers of 101K shares (+18.1%). 28 opened a new position and 30 sold out entirely.

Bought, Q2 2026 104 institutions, 28 of them new holders Sold, Q2 2026 80 institutions, 30 of them sold out

Net change, all compared +787K shares (+1.3%)

Net change, active managers +405K shares (+1.0%), 24 bought, 18 sold

Buyers versus sellers

institutions compared, 220

104 bought 36 80 sold

Active managers and hedge funds 24 bought · 18 sold · +405K

Index fund managers 3 bought · 1 sold · +101K

Other institutions 77 bought · 61 sold · +282K

Biggest buyers

by change in shares held

Biggest buyers
Institution	Change in shares	Shares June 30, 2026	Value
RTW Investments, LP Hedge fund	+1.6M New position	1.6M	$86.3M
Orbimed Advisors LLC	+734K +49.7%	2.2M	$119M
Morgan Stanley	+501K +21.7%	2.8M	$151M
Deep Track Capital, LP Hedge fund	+460K +10.8%	4.7M	$254M
Bank Of America Corp	+336K +148.1%	563K	$30.2M
Davern Capital Partners, LP	+320K +252.7%	446K	$23.9M
Deerfield Management Company, L.P. Hedge fund	+318K +41.4%	1.1M	$58.3M
Parkman Healthcare Partners LLC	+254K +109.3%	486K	$26.1M
Aberdeen Group PLC	+248K +63.3%	640K	$34.3M
American Century Companies Inc Active manager	+244K +17.0%	1.7M	$90.3M
Marshall Wace, LLP Hedge fund	+198K +287.2%	268K	$14.4M
Nextbio Capital Management LP	+179K +134.5%	312K	$16.8M
UBS Group AG	+166K +78.0%	379K	$20.3M
Centerbook Partners LP Hedge fund	+127K +597.0%	148K	$7.9M
Wellington Management Group LLP Active manager	+119K +1.6%	7.4M	$396M
Squarepoint Ops LLC Hedge fund	+103K +454.5%	126K	$6.7M
Susquehanna Portfolio Strategies, LLC	+88K +146.1%	149K	$8M
Exoduspoint Capital Management, LP Hedge fund	+78K New position	78K	$4.2M
Adage Capital Partners Gp, L.L.C. Hedge fund	+75K New position	75K	$4M
Blackrock, Inc. Index funds	+69K +15.7%	511K	$27.4M

Biggest buyers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
RTW Investments, LP Hedge fund	+1.6M New position	1.6M	$86.3M
Deep Track Capital, LP Hedge fund	+460K +10.8%	4.7M	$254M
Deerfield Management Company, L.P. Hedge fund	+318K +41.4%	1.1M	$58.3M
American Century Companies Inc Active manager	+244K +17.0%	1.7M	$90.3M
Marshall Wace, LLP Hedge fund	+198K +287.2%	268K	$14.4M
Centerbook Partners LP Hedge fund	+127K +597.0%	148K	$7.9M
Wellington Management Group LLP Active manager	+119K +1.6%	7.4M	$396M
Squarepoint Ops LLC Hedge fund	+103K +454.5%	126K	$6.7M
Exoduspoint Capital Management, LP Hedge fund	+78K New position	78K	$4.2M
Adage Capital Partners Gp, L.L.C. Hedge fund	+75K New position	75K	$4M

Biggest sellers

by change in shares held

Biggest sellers
Institution	Change in shares	Shares June 30, 2026	Value
Price T Rowe Associates Inc Active manager	−1.2M −57.7%	846K	$45.4M
FMR LLC Active manager	−593K −7.1%	7.8M	$419M
Paradigm Biocapital Advisors LP	−545K Sold out	0	—
Siren, L.L.C.	−456K −34.3%	873K	$46.9M
Stempoint Capital LP	−362K −90.5%	38K	$2M
Balyasny Asset Management L.P. Hedge fund	−305K Sold out	0	—
Pentwater Capital Management LP Hedge fund	−245K Sold out	0	—
Sio Capital Management, LLC	−209K Sold out	0	—
Jpmorgan Chase & Co	−209K −98.1%	3,984	$205,933
Holocene Advisors, LP Hedge fund	−159K Sold out	0	—
Voloridge Investment Management, LLC Hedge fund	−143K −56.0%	112K	$6M
Tcg Crossover Management, LLC	−140K Sold out	0	—
TD Asset Management Inc	−136K −66.3%	69K	$3.7M
Capitolis Liquid Global Markets LLC	−110K −9.6%	1.0M	$55.9M
Trexquant Investment LP Hedge fund	−108K Sold out	0	—
Cormorant Asset Management, LP Hedge fund	−100K −57.1%	75K	$4M
Bvf Inc	−93K −2.7%	3.4M	$181M
National Bank Of Canada	−90K −29.3%	216K	$11.6M
D. E. Shaw & Co., Inc. Hedge fund	−89K −43.7%	115K	$6.2M
Millennium Management LLC Hedge fund	−79K −47.0%	90K	$4.8M

Biggest sellers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Price T Rowe Associates Inc Active manager	−1.2M −57.7%	846K	$45.4M
FMR LLC Active manager	−593K −7.1%	7.8M	$419M
Balyasny Asset Management L.P. Hedge fund	−305K Sold out	0	—
Pentwater Capital Management LP Hedge fund	−245K Sold out	0	—
Holocene Advisors, LP Hedge fund	−159K Sold out	0	—
Voloridge Investment Management, LLC Hedge fund	−143K −56.0%	112K	$6M
Trexquant Investment LP Hedge fund	−108K Sold out	0	—
Cormorant Asset Management, LP Hedge fund	−100K −57.1%	75K	$4M
D. E. Shaw & Co., Inc. Hedge fund	−89K −43.7%	115K	$6.2M
Millennium Management LLC Hedge fund	−79K −47.0%	90K	$4.8M

New positions

largest by value

Institution	Shares	Value June 30, 2026
RTW Investments, LPHedge fund	1.6M	$86.3M
Exoduspoint Capital Management, LPHedge fund	78K	$4.2M
Adage Capital Partners Gp, L.L.C.Hedge fund	75K	$4M
Y-Intercept (Hong Kong) Ltd	28K	$1.5M
Nomura Holdings Inc	23K	$1.2M
Handelsbanken Fonder AB	19K	$1M
ADAR1 Capital Management, LLCHedge fund	18K	$939,225
Gladstone Institutional Advisory LLC	13K	$712,469
Fulcrum Asset Management LLP	13K	$684,996
Fox Run Management, L.L.C.	11K	$578,348

Sold out

largest by value

Institution	Shares	Value March 31, 2026
Paradigm Biocapital Advisors LP	545K	$26.3M
Balyasny Asset Management L.P.Hedge fund	305K	$14.7M
Pentwater Capital Management LPHedge fund	245K	$11.8M
Sio Capital Management, LLC	209K	$10.1M
Holocene Advisors, LPHedge fund	159K	$7.7M
Tcg Crossover Management, LLC	140K	$6.8M
Trexquant Investment LPHedge fund	108K	$5.2M
Diadema Partners LP	72K	$3.5M
Renaissance Technologies LLCHedge fund	56K	$2.7M
Monashee Investment Management LLC	50K	$2.4M

Who holds the shares

13F holdings at June 30, 2026

Institutions reporting: 191
Ten largest holders: 64.4%
Index fund managers: 1.0%
Active managers and hedge funds: 60.3%

Buying and selling by type of institution, March 31, 2026 to June 30, 2026
Type	Bought	Sold	New	Sold out	Net change in shares	Net %
Active managers and hedge funds	24	18	5	7	+405K	+1.0%
Index fund managers	3	1	1	0	+101K	+18.1%
Other institutions	77	61	22	23	+282K	+1.4%

Active managers and hedge funds: a list we maintain of about 400 well-known stock-picking firms and hedge funds, matched by SEC registration number (CIK) and checked against the filer names each quarter. Index fund managers: the large index houses, such as BlackRock, Vanguard, State Street, Geode and Northern Trust. Every other filer (banks, brokers, wealth managers, pension funds, insurers and firms not on the list) counts as another institution. A firm that files under several SEC registrations appears once for each.

What these filings can and cannot tell you

Form 13F lists the long positions in US-listed shares held by investment managers with more than $100 million in such holdings. Managers file it up to 45 days after each quarter ends, so this page shows what funds held at the end of each quarter, not what they are doing now: a position may have changed since. Short positions, most derivatives and smaller managers are not included, and a cut can mean a fund lost clients or rebalanced rather than a view on Structure Therapeutics.

Only managers that filed a holdings report for both quarters are compared (220 here). 3 other holders are left out: first-time or late filers, firms that changed their SEC registration, and filings that withheld positions under confidential treatment, any of which would otherwise look like a new position or a sale. Figures are as reported by each manager in the SEC's quarterly 13F data sets; option positions are excluded.

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