undamentalytics Newsletter

Maze Therapeutics, Inc.: which funds bought and sold

Institutions that bought and sold Maze Therapeutics shares in Q2 2026, from the holdings they reported to the SEC on Form 13F for March 31, 2026 and June 30, 2026.

Between March 31, 2026 and June 30, 2026, 102 institutions that filed 13F reports for both quarters added to or opened positions in Maze Therapeutics, and 76 cut or closed them. Together they added a net 6.3M shares, +13.0% on what they held at the start of the quarter. Active managers and hedge funds on our list were net buyers of 5.2M shares (+38.2%); index fund managers were net buyers of 2.3M shares (+38.8%). 37 opened a new position and 38 sold out entirely.

Bought, Q2 2026 102 institutions, 37 of them new holders Sold, Q2 2026 76 institutions, 38 of them sold out
Net change, all compared +6.3M shares (+13.0%)
Net change, active managers +5.2M shares (+38.2%), 29 bought, 22 sold

Buyers versus sellers

institutions compared, 197
Active managers and hedge funds 29 bought · 22 sold · +5.2M
Index fund managers 10 bought · 0 sold · +2.3M
Other institutions 63 bought · 54 sold · −1.2M

Biggest buyers

by change in shares held
Biggest buyers
Institution Change in shares Shares June 30, 2026 Value
T. Rowe Price Investment Management, Inc. Active manager +2.6M New position 2.6M $77.7M
Braidwell LP Hedge fund +1.1M New position 1.1M $34M
Blackrock, Inc. Index funds +932K +36.3% 3.5M $105M
Jpmorgan Chase & Co +906K +1549.4% 964K $28M
Farallon Capital Management, L.L.C. Hedge fund +735K +197.0% 1.1M $33.1M
Logos Global Management LP Hedge fund +700K +56.7% 1.9M $57.7M
Marshall Wace, LLP Hedge fund +604K +194.4% 915K $27.3M
Frazier Life Sciences Management, L.P. +466K +10.2% 5.0M $150M
State Street Corp Index funds +361K +56.7% 998K $29.8M
Vanguard Capital Management LLC Index funds +343K +23.9% 1.8M $53.1M
Driehaus Capital Management LLC Active manager +319K +50.1% 955K $28.5M
ADAR1 Capital Management, LLC Hedge fund +289K +577.3% 339K $10.1M
Hudson Bay Capital Management LP Hedge fund +262K +3212.9% 270K $8.1M
Geode Capital Management, LLC Index funds +258K +43.0% 858K $25.6M
Deep Track Capital, LP Hedge fund +255K +7.3% 3.7M $111M
RTW Investments, LP Hedge fund +212K New position 212K $6.3M
Vanguard Portfolio Management LLC Index funds +198K +101.0% 393K $11.7M
FMR LLC Active manager +193K +22.3% 1.1M $31.5M
Sphera Funds Management Ltd. +190K +83.7% 418K $12.5M
Exoduspoint Capital Management, LP Hedge fund +183K New position 183K $5.5M

Biggest sellers

by change in shares held
Biggest sellers
Institution Change in shares Shares June 30, 2026 Value
Paradigm Biocapital Advisors LP −2.7M Sold out 0 —
Adage Capital Partners Gp, L.L.C. Hedge fund −930K −78.9% 248K $7.4M
Cormorant Asset Management, LP Hedge fund −750K Sold out 0 —
Caligan Partners LP Hedge fund −615K Sold out 0 —
Balyasny Asset Management L.P. Hedge fund −441K −95.6% 20K $602,470
Washington University −281K Sold out 0 —
Freestone Grove Partners LP Hedge fund −235K Sold out 0 —
Spruce Street Capital LP −200K Sold out 0 —
Foresite Capital Management Iv, LLC −157K Sold out 0 —
Holocene Advisors, LP Hedge fund −136K Sold out 0 —
Atika Capital Management LLC −112K Sold out 0 —
Integral Health Asset Management, LLC −100K Sold out 0 —
Boothbay Fund Management, LLC Hedge fund −96K −33.6% 189K $5.6M
Ensign Peak Advisors, Inc −84K −45.3% 102K $3M
Morgan Stanley −70K −34.0% 135K $4M
Invesco Ltd. −58K −67.2% 28K $846,620
Aquatic Capital Management LLC −35K Sold out 0 —
D. E. Shaw & Co., Inc. Hedge fund −34K −73.7% 12K $358,647
Parkman Healthcare Partners LLC −32K Sold out 0 —
Twinbeech Capital LP −31K Sold out 0 —

New positions

largest by value
InstitutionSharesValue June 30, 2026
T. Rowe Price Investment Management, Inc.Active manager 2.6M $77.7M
Braidwell LPHedge fund 1.1M $34M
RTW Investments, LPHedge fund 212K $6.3M
Exoduspoint Capital Management, LPHedge fund 183K $5.5M
Algert Global LLCHedge fund 93K $2.8M
Trexquant Investment LPHedge fund 82K $2.4M
Jacobs Levy Equity Management, IncActive manager 65K $2M
Jump Financial, LLC 47K $1.4M
Swiss National Bank 47K $1.4M
Quadrature Capital LtdHedge fund 30K $896,602

Sold out

largest by value
InstitutionSharesValue March 31, 2026
Paradigm Biocapital Advisors LP 2.7M $81.9M
Cormorant Asset Management, LPHedge fund 750K $22.4M
Caligan Partners LPHedge fund 615K $18.4M
Washington University 281K $8.4M
Freestone Grove Partners LPHedge fund 235K $7M
Spruce Street Capital LP 200K $6M
Foresite Capital Management Iv, LLC 157K $4.7M
Holocene Advisors, LPHedge fund 136K $4.1M
Atika Capital Management LLC 112K $3.3M
Integral Health Asset Management, LLC 100K $3M

Who holds the shares

13F holdings at June 30, 2026
Institutions reporting
161
Ten largest holders
55.2%
of 13F-reported shares
Index fund managers
14.3%
of 13F-reported shares
Active managers and hedge funds
32.3%
of 13F-reported shares
Buying and selling by type of institution, March 31, 2026 to June 30, 2026
TypeBoughtSoldNewSold outNet change in sharesNet %
Active managers and hedge funds 29 22 10 12 +5.2M +38.2%
Index fund managers 10 0 1 0 +2.3M +38.8%
Other institutions 63 54 26 26 −1.2M −4.2%

Active managers and hedge funds: a list we maintain of about 400 well-known stock-picking firms and hedge funds, matched by SEC registration number (CIK) and checked against the filer names each quarter. Index fund managers: the large index houses, such as BlackRock, Vanguard, State Street, Geode and Northern Trust. Every other filer (banks, brokers, wealth managers, pension funds, insurers and firms not on the list) counts as another institution. A firm that files under several SEC registrations appears once for each.

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