Milestone Pharmaceuticals Inc.: which funds bought and sold

Institutions that bought and sold Milestone Pharmaceuticals shares in Q2 2026, from the holdings they reported to the SEC on Form 13F for March 31, 2026 and June 30, 2026.

Between March 31, 2026 and June 30, 2026, 29 institutions that filed 13F reports for both quarters added to or opened positions in Milestone Pharmaceuticals, and 35 cut or closed them. Together they added a net 11.3M shares, +28.7% on what they held at the start of the quarter. Active managers and hedge funds on our list were net buyers of 6.2M shares (+39.0%); index fund managers were net sellers of 39K shares (−37.8%). 6 opened a new position and 12 sold out entirely.

Bought, Q2 2026 29 institutions, 6 of them new holders Sold, Q2 2026 35 institutions, 12 of them sold out

Net change, all compared +11.3M shares (+28.7%)

Net change, active managers +6.2M shares (+39.0%), 5 bought, 8 sold

Buyers versus sellers

institutions compared, 90

29 bought 26 35 sold

Active managers and hedge funds 5 bought · 8 sold · +6.2M

Index fund managers 1 bought · 1 sold · −39K

Other institutions 23 bought · 26 sold · +5.2M

Biggest buyers

by change in shares held

Biggest buyers
Institution	Change in shares	Shares June 30, 2026	Value
Point72 Asset Management, L.P. Hedge fund	+4.3M +398.4%	5.4M	$7.3M
Propel Bio Management, LLC	+3.3M +80.4%	7.4M	$10M
Kalehua Capital Management LLC	+2.5M New position	2.5M	$3.4M
Simplify Asset Management Inc.	+1.8M +122.3%	3.3M	$4.5M
Millennium Management LLC Hedge fund	+1.6M +103.5%	3.1M	$4.2M
RTW Investments, LP Hedge fund	+1.5M +23.7%	7.8M	$10.5M
Boothbay Fund Management, LLC Hedge fund	+294K +174.3%	463K	$619,976
Wealthspire Advisors, LLC	+130K +1223.1%	141K	$188,443
Cascades Capital Asset Management, LLC	+84K New position	84K	$112,037
Aptus Capital Advisors, LLC	+59K +21.1%	339K	$454,863
Guardian Wealth Advisors, LLC / Nc	+59K +21.1%	339K	$454,863
Tru Independence Asset Management 2, LLC	+50K +50.0%	150K	$201,000
LPL Financial LLC	+28K +14.2%	221K	$295,970
Two Sigma Securities, LLC	+17K New position	17K	$22,438
Bay Rivers Group	+17K +55.9%	47K	$62,488
Tower Research Capital LLC (TRC)	+15K +164.4%	24K	$32,408
Winton Group Ltd Hedge fund	+14K New position	14K	$19,162
Virtu Financial LLC	+12K New position	12K	$16,000
Hightower Advisors, LLC	+10K +100.0%	20K	$26,800
Exit Wealth Advisors, Llc.	+7,692 +51.3%	23K	$30,407

Biggest buyers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Point72 Asset Management, L.P. Hedge fund	+4.3M +398.4%	5.4M	$7.3M
Millennium Management LLC Hedge fund	+1.6M +103.5%	3.1M	$4.2M
RTW Investments, LP Hedge fund	+1.5M +23.7%	7.8M	$10.5M
Boothbay Fund Management, LLC Hedge fund	+294K +174.3%	463K	$619,976
Winton Group Ltd Hedge fund	+14K New position	14K	$19,162

Biggest sellers

by change in shares held

Biggest sellers
Institution	Change in shares	Shares June 30, 2026	Value
Goldman Sachs Group Inc	−2.0M Sold out	0	—
Balyasny Asset Management L.P. Hedge fund	−631K −74.1%	220K	$295,467
Two Sigma Investments, LP Hedge fund	−277K −12.0%	2.0M	$2.7M
Citadel Advisors LLC Hedge fund	−164K −83.3%	33K	$44,069
Susquehanna International Group, LLP	−159K −30.7%	360K	$482,259
Marshall Wace, LLP Hedge fund	−147K −7.6%	1.8M	$2.4M
Renaissance Technologies LLC Hedge fund	−130K Sold out	0	—
Group One Trading LLC	−130K −99.8%	224	$300
Squarepoint Ops LLC Hedge fund	−105K −31.2%	232K	$310,644
Jane Street Group, LLC	−102K −63.8%	58K	$77,435
Simplex Trading, LLC	−95K −63.7%	54K	$72,589
Xtx Topco Ltd	−94K −78.2%	26K	$35,265
Morgan Stanley	−89K −12.3%	635K	$851,183
Quadrature Capital Ltd Hedge fund	−84K −56.6%	65K	$86,646
Seven Fleet Capital Management LP	−63K −18.9%	270K	$362,112
HRT Financial LP	−62K Sold out	0	—
Invesco Ltd.	−41K Sold out	0	—
Northern Trust Corp Index funds	−39K Sold out	0	—
Cambridge Investment Research Advisors, Inc.	−33K −54.8%	27K	$36,000
UBS Group AG	−30K −6.0%	465K	$623,641

Biggest sellers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Balyasny Asset Management L.P. Hedge fund	−631K −74.1%	220K	$295,467
Two Sigma Investments, LP Hedge fund	−277K −12.0%	2.0M	$2.7M
Citadel Advisors LLC Hedge fund	−164K −83.3%	33K	$44,069
Marshall Wace, LLP Hedge fund	−147K −7.6%	1.8M	$2.4M
Renaissance Technologies LLC Hedge fund	−130K Sold out	0	—
Squarepoint Ops LLC Hedge fund	−105K −31.2%	232K	$310,644
Quadrature Capital Ltd Hedge fund	−84K −56.6%	65K	$86,646
Acadian Asset Management LLC Active manager	−20K Sold out	0	—

New positions

largest by value

Institution	Shares	Value June 30, 2026
Kalehua Capital Management LLC	2.5M	$3.4M
Cascades Capital Asset Management, LLC	84K	$112,037
Two Sigma Securities, LLC	17K	$22,438
Winton Group LtdHedge fund	14K	$19,162
Virtu Financial LLC	12K	$16,000
Arax Advisory Partners	3,053	$4,090

Sold out

largest by value

Institution	Shares	Value March 31, 2026
Goldman Sachs Group Inc	2.0M	$2.4M
Renaissance Technologies LLCHedge fund	130K	$154,349
HRT Financial LP	62K	$74,000
Invesco Ltd.	41K	$49,214
Northern Trust CorpIndex funds	39K	$46,147
Gsa Capital Partners LLP	27K	$32,000
Acadian Asset Management LLCActive manager	20K	$24,000
Sjs Investment Consulting Inc.	15K	$17,850
Imc-Chicago, LLC	11K	$13,022
Bayesian Capital Management, LP	10K	$11,918

Who holds the shares

13F holdings at June 30, 2026

Institutions reporting: 78
Ten largest holders: 85.4%
Index fund managers: 0.1%
Active managers and hedge funds: 43.3%

Buying and selling by type of institution, March 31, 2026 to June 30, 2026
Type	Bought	Sold	New	Sold out	Net change in shares	Net %
Active managers and hedge funds	5	8	1	2	+6.2M	+39.0%
Index fund managers	1	1	0	1	−39K	−37.8%
Other institutions	23	26	5	9	+5.2M	+22.1%

Active managers and hedge funds: a list we maintain of about 400 well-known stock-picking firms and hedge funds, matched by SEC registration number (CIK) and checked against the filer names each quarter. Index fund managers: the large index houses, such as BlackRock, Vanguard, State Street, Geode and Northern Trust. Every other filer (banks, brokers, wealth managers, pension funds, insurers and firms not on the list) counts as another institution. A firm that files under several SEC registrations appears once for each.

What these filings can and cannot tell you

Form 13F lists the long positions in US-listed shares held by investment managers with more than $100 million in such holdings. Managers file it up to 45 days after each quarter ends, so this page shows what funds held at the end of each quarter, not what they are doing now: a position may have changed since. Short positions, most derivatives and smaller managers are not included, and a cut can mean a fund lost clients or rebalanced rather than a view on Milestone Pharmaceuticals.

Only managers that filed a holdings report for both quarters are compared (90 here). 2 other holders are left out: first-time or late filers, firms that changed their SEC registration, and filings that withheld positions under confidential treatment, any of which would otherwise look like a new position or a sale. Figures are as reported by each manager in the SEC's quarterly 13F data sets; option positions are excluded.

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