Opko Health, Inc.: which funds bought and sold

Institutions that bought and sold Opko Health shares in Q2 2026, from the holdings they reported to the SEC on Form 13F for March 31, 2026 and June 30, 2026.

Between March 31, 2026 and June 30, 2026, 96 institutions that filed 13F reports for both quarters added to or opened positions in Opko Health, and 82 cut or closed them. Together they added a net 1.8M shares, +0.9% on what they held at the start of the quarter. Active managers and hedge funds on our list were net buyers of 3.3M shares (+6.3%); index fund managers were net buyers of 2.5M shares (+2.6%). 21 opened a new position and 31 sold out entirely.

Bought, Q2 2026 96 institutions, 21 of them new holders Sold, Q2 2026 82 institutions, 31 of them sold out

Net change, all compared +1.8M shares (+0.9%)

Net change, active managers +3.3M shares (+6.3%), 11 bought, 9 sold

Buyers versus sellers

institutions compared, 248

96 bought 70 82 sold

Active managers and hedge funds 11 bought · 9 sold · +3.3M

Index fund managers 9 bought · 2 sold · +2.5M

Other institutions 76 bought · 71 sold · −4.1M

Biggest buyers

by change in shares held

Biggest buyers
Institution	Change in shares	Shares June 30, 2026	Value
Highbridge Capital Management LLC Hedge fund	+3.6M New position	3.6M	$5.4M
State Street Corp Index funds	+808K +8.5%	10.3M	$15.5M
Morgan Stanley	+779K +65.1%	2.0M	$3M
Blackrock, Inc. Index funds	+747K +2.1%	37.0M	$55.5M
California State Teachers Retirement System	+547K +132.2%	961K	$1.4M
AQR Capital Management LLC Hedge fund	+476K +62.3%	1.2M	$1.9M
Vanguard Capital Management LLC Index funds	+470K +3.2%	15.0M	$22.5M
Algert Global LLC Hedge fund	+397K New position	397K	$595,545
Geode Capital Management, LLC Index funds	+280K +2.5%	11.6M	$17.4M
Van Eck Associates Corp	+279K +174.0%	439K	$657,968
Whitefort Capital Management, LP	+258K +6.1%	4.5M	$6.8M
Susquehanna International Group, LLP	+232K +59.3%	624K	$935,342
Wells Fargo & Company	+191K +117.7%	354K	$531,059
Russell Investments Group, Ltd.	+184K +578.3%	216K	$323,730
Citigroup Inc	+166K +493.4%	200K	$299,737
Vanguard Portfolio Management LLC Index funds	+165K +1.1%	14.9M	$22.4M
Northern Trust Corp Index funds	+137K +3.8%	3.8M	$5.6M
Arax Advisory Partners	+93K +31850.9%	94K	$140,425
Rpg Family Wealth Advisory, LLC	+89K +100.0%	177K	$265,856
Cambridge Investment Research Advisors, Inc.	+77K +85.4%	167K	$252,000

Biggest buyers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Highbridge Capital Management LLC Hedge fund	+3.6M New position	3.6M	$5.4M
AQR Capital Management LLC Hedge fund	+476K +62.3%	1.2M	$1.9M
Algert Global LLC Hedge fund	+397K New position	397K	$595,545
Millennium Management LLC Hedge fund	+72K New position	72K	$108,452
Point72 Asset Management, L.P. Hedge fund	+52K +55.6%	145K	$217,851
Price T Rowe Associates Inc Active manager	+51K +12.6%	456K	$684,000
Squarepoint Ops LLC Hedge fund	+42K New position	42K	$62,387
Schonfeld Strategic Advisors LLC Hedge fund	+27K New position	27K	$40,459
Alliancebernstein L.P. Active manager	+19K +4.6%	443K	$504,655
Two Sigma Investments, LP Hedge fund	+5,801 +3.4%	176K	$263,702

Biggest sellers

by change in shares held

Biggest sellers
Institution	Change in shares	Shares June 30, 2026	Value
UBS Group AG	−1.1M −17.5%	5.0M	$7.5M
Jane Street Group, LLC	−885K −79.4%	229K	$344,181
Tejara Capital Ltd	−878K Sold out	0	—
Gsa Capital Partners LLP	−664K Sold out	0	—
Citadel Advisors LLC Hedge fund	−659K −31.7%	1.4M	$2.1M
Goldman Sachs Group Inc	−640K −8.3%	7.0M	$10.6M
Pfg Investments, LLC	−502K −45.1%	610K	$915,737
First Trust Advisors LP	−500K Sold out	0	—
Qube Research & Technologies Ltd Hedge fund	−404K Sold out	0	—
Bank Of America Corp	−346K −30.3%	796K	$1.2M
Entrypoint Capital, LLC	−342K Sold out	0	—
Jpmorgan Chase & Co	−340K −66.9%	168K	$254,141
Dimensional Fund Advisors LP	−292K −18.7%	1.3M	$1.9M
Zazove Associates LLC	−200K −66.7%	100K	$150,000
Xtx Topco Ltd	−145K −33.6%	286K	$429,260
Connor, Clark & Lunn Investment Management Ltd.	−111K −21.2%	412K	$618,077
Renaissance Technologies LLC Hedge fund	−110K Sold out	0	—
Invesco Ltd.	−108K −13.6%	685K	$1M
Tower Research Capital LLC (TRC)	−104K −80.8%	25K	$37,078
UBS Am, A Distinct Business Unit Of UBS Asset Management Americas LLC	−101K −14.9%	574K	$861,163

Biggest sellers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Citadel Advisors LLC Hedge fund	−659K −31.7%	1.4M	$2.1M
Qube Research & Technologies Ltd Hedge fund	−404K Sold out	0	—
Renaissance Technologies LLC Hedge fund	−110K Sold out	0	—
Quadrature Capital Ltd Hedge fund	−89K Sold out	0	—
Brevan Howard Capital Management LP Hedge fund	−46K Sold out	0	—
Intech Investment Management LLC Active manager	−40K −31.7%	86K	$128,825
Graham Capital Management, L.P. Hedge fund	−30K −56.8%	23K	$34,251
FMR LLC Active manager	−26K −62.9%	15K	$23,004
Victory Capital Management Inc Active manager	−645 −1.5%	44K	$65,435

New positions

largest by value

Institution	Shares	Value June 30, 2026
Highbridge Capital Management LLCHedge fund	3.6M	$5.4M
Algert Global LLCHedge fund	397K	$595,545
Millennium Management LLCHedge fund	72K	$108,452
Squarepoint Ops LLCHedge fund	42K	$62,387
Schonfeld Strategic Advisors LLCHedge fund	27K	$40,459
Diversify Advisory Services, LLC	30K	$37,200
Two Sigma Securities, LLC	18K	$27,405
Axq Capital, LP	15K	$22,982
Merit Financial Group, LLC	15K	$21,910
Gts Securities LLC	14K	$21,141

Sold out

largest by value

Institution	Shares	Value March 31, 2026
Tejara Capital Ltd	878K	$1M
Gsa Capital Partners LLP	664K	$757,000
First Trust Advisors LP	500K	$570,311
Qube Research & Technologies LtdHedge fund	404K	$460,968
Entrypoint Capital, LLC	342K	$390,075
Renaissance Technologies LLCHedge fund	110K	$124,879
HRT Financial LP	91K	$103,000
Quadrature Capital LtdHedge fund	89K	$101,388
Brevan Howard Capital Management LPHedge fund	46K	$52,348
Lgl Partners, LLC	45K	$50,738

Who holds the shares

13F holdings at June 30, 2026

Institutions reporting: 220
Ten largest holders: 77.3%
Index fund managers: 49.0%
Active managers and hedge funds: 27.9%

Buying and selling by type of institution, March 31, 2026 to June 30, 2026
Type	Bought	Sold	New	Sold out	Net change in shares	Net %
Active managers and hedge funds	11	9	5	4	+3.3M	+6.3%
Index fund managers	9	2	0	0	+2.5M	+2.6%
Other institutions	76	71	16	27	−4.1M	−8.1%

Active managers and hedge funds: a list we maintain of about 400 well-known stock-picking firms and hedge funds, matched by SEC registration number (CIK) and checked against the filer names each quarter. Index fund managers: the large index houses, such as BlackRock, Vanguard, State Street, Geode and Northern Trust. Every other filer (banks, brokers, wealth managers, pension funds, insurers and firms not on the list) counts as another institution. A firm that files under several SEC registrations appears once for each.

What these filings can and cannot tell you

Form 13F lists the long positions in US-listed shares held by investment managers with more than $100 million in such holdings. Managers file it up to 45 days after each quarter ends, so this page shows what funds held at the end of each quarter, not what they are doing now: a position may have changed since. Short positions, most derivatives and smaller managers are not included, and a cut can mean a fund lost clients or rebalanced rather than a view on Opko Health.

Only managers that filed a holdings report for both quarters are compared (248 here). 9 other holders are left out: first-time or late filers, firms that changed their SEC registration, and filings that withheld positions under confidential treatment, any of which would otherwise look like a new position or a sale. Figures are as reported by each manager in the SEC's quarterly 13F data sets; option positions are excluded.

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