Puma Biotechnology, Inc.: which funds bought and sold

Institutions that bought and sold Puma Biotechnology shares in Q2 2026, from the holdings they reported to the SEC on Form 13F for March 31, 2026 and June 30, 2026.

Between March 31, 2026 and June 30, 2026, 81 institutions that filed 13F reports for both quarters added to or opened positions in Puma Biotechnology, and 66 cut or closed them. Together they added a net 836K shares, +2.2% on what they held at the start of the quarter. Active managers and hedge funds on our list were net buyers of 386 shares (0.0%); index fund managers were net buyers of 727K shares (+7.2%). 21 opened a new position and 15 sold out entirely.

Bought, Q2 2026 81 institutions, 21 of them new holders Sold, Q2 2026 66 institutions, 15 of them sold out

Net change, all compared +836K shares (+2.2%)

Net change, active managers +386 shares (0.0%), 15 bought, 14 sold

Buyers versus sellers

institutions compared, 174

81 bought 27 66 sold

Active managers and hedge funds 15 bought · 14 sold · +386

Index fund managers 10 bought · 0 sold · +727K

Other institutions 56 bought · 52 sold · +109K

Biggest buyers

by change in shares held

Biggest buyers
Institution	Change in shares	Shares June 30, 2026	Value
LSV Asset Management Active manager	+435K +36.8%	1.6M	$13.1M
American Century Companies Inc Active manager	+404K +21.1%	2.3M	$18.8M
Geode Capital Management, LLC Index funds	+322K +31.7%	1.3M	$10.9M
Invesco Ltd.	+206K +216.7%	301K	$2.4M
Blackrock, Inc. Index funds	+206K +5.7%	3.8M	$30.9M
Two Sigma Investments, LP Hedge fund	+128K +981.4%	141K	$1.1M
Wellington Management Group LLP Active manager	+126K New position	126K	$1M
UBS Group AG	+103K +19.2%	637K	$5.2M
Vanguard Portfolio Management LLC Index funds	+91K +5.2%	1.8M	$14.8M
Dimensional Fund Advisors LP	+82K +5.7%	1.5M	$12.3M
Trexquant Investment LP Hedge fund	+72K New position	72K	$585,729
Canada Pension Plan Investment Board	+51K +222.4%	74K	$596,085
State Board Of Administration Of Florida Retirement System	+36K +13.3%	309K	$2.5M
State Street Corp Index funds	+35K +3.8%	952K	$7.7M
Globeflex Capital L P	+33K +9.5%	383K	$3.1M
Vise Technologies, Inc.	+32K +78.7%	72K	$584,163
Y-Intercept (Hong Kong) Ltd	+26K New position	26K	$212,660
Martingale Asset Management L P Active manager	+25K New position	25K	$205,703
Xtx Topco Ltd	+25K +166.6%	40K	$326,801
Panagora Asset Management Inc Active manager	+23K +11.6%	218K	$1.8M

Biggest buyers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
LSV Asset Management Active manager	+435K +36.8%	1.6M	$13.1M
American Century Companies Inc Active manager	+404K +21.1%	2.3M	$18.8M
Two Sigma Investments, LP Hedge fund	+128K +981.4%	141K	$1.1M
Wellington Management Group LLP Active manager	+126K New position	126K	$1M
Trexquant Investment LP Hedge fund	+72K New position	72K	$585,729
Martingale Asset Management L P Active manager	+25K New position	25K	$205,703
Panagora Asset Management Inc Active manager	+23K +11.6%	218K	$1.8M
FMR LLC Active manager	+20K +10.2%	211K	$1.7M
Bridgeway Capital Management, LLC Active manager	+16K +2.1%	792K	$6.4M
Federated Hermes, Inc. Active manager	+13K +5.5%	251K	$2M

Biggest sellers

by change in shares held

Biggest sellers
Institution	Change in shares	Shares June 30, 2026	Value
Millennium Management LLC Hedge fund	−875K −59.2%	602K	$4.9M
Connor, Clark & Lunn Investment Management Ltd.	−140K −17.9%	643K	$5.2M
Renaissance Technologies LLC Hedge fund	−106K −5.5%	1.8M	$14.9M
Morgan Stanley	−94K −26.1%	266K	$2.2M
Sei Investments Co	−90K −17.6%	419K	$3.4M
AQR Capital Management LLC Hedge fund	−75K −9.4%	725K	$5.9M
Franklin Resources Inc Active manager	−43K −20.1%	172K	$1.4M
Prudential Financial Inc	−39K −15.6%	214K	$1.7M
State Of Wyoming	−36K −47.5%	40K	$323,046
D. E. Shaw & Co., Inc. Hedge fund	−35K −9.9%	316K	$2.6M
Openarc Corporate Advisory, LLC	−30K −33.5%	59K	$482,472
Citadel Advisors LLC Hedge fund	−30K Sold out	0	—
Virtus Advisers, LLC	−29K Sold out	0	—
Engineers Gate Manager LP Hedge fund	−29K Sold out	0	—
Winton Group Ltd Hedge fund	−26K −38.9%	41K	$328,528
Ritholtz Wealth Management	−25K −3.2%	750K	$6.1M
Evergreen Capital Management LLC	−22K −23.2%	74K	$597,960
State Of Wisconsin Investment Board	−20K −9.8%	188K	$1.5M
Lazard Asset Management LLC Active manager	−18K Sold out	0	—
Quadrature Capital Ltd Hedge fund	−17K Sold out	0	—

Biggest sellers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Millennium Management LLC Hedge fund	−875K −59.2%	602K	$4.9M
Renaissance Technologies LLC Hedge fund	−106K −5.5%	1.8M	$14.9M
AQR Capital Management LLC Hedge fund	−75K −9.4%	725K	$5.9M
Franklin Resources Inc Active manager	−43K −20.1%	172K	$1.4M
D. E. Shaw & Co., Inc. Hedge fund	−35K −9.9%	316K	$2.6M
Citadel Advisors LLC Hedge fund	−30K Sold out	0	—
Engineers Gate Manager LP Hedge fund	−29K Sold out	0	—
Winton Group Ltd Hedge fund	−26K −38.9%	41K	$328,528
Lazard Asset Management LLC Active manager	−18K Sold out	0	—
Quadrature Capital Ltd Hedge fund	−17K Sold out	0	—

New positions

largest by value

Institution	Shares	Value June 30, 2026
Wellington Management Group LLPActive manager	126K	$1M
Trexquant Investment LPHedge fund	72K	$585,729
Y-Intercept (Hong Kong) Ltd	26K	$212,660
Martingale Asset Management L PActive manager	25K	$205,703
Spark Investment Management LLC	17K	$137,870
Lido Advisors, LLC	15K	$122,015
R Squared Ltd	12K	$97,247
Vanguard Personalized Indexing Management, LLCIndex funds	10K	$84,409
Intech Investment Management LLCActive manager	10K	$82,803
Kemnay Advisory Services Inc.	3,370	$27,331

Sold out

largest by value

Institution	Shares	Value March 31, 2026
Citadel Advisors LLCHedge fund	30K	$191,438
Virtus Advisers, LLC	29K	$187,527
Engineers Gate Manager LPHedge fund	29K	$182,754
Lazard Asset Management LLCActive manager	18K	$114,828
Quadrature Capital LtdHedge fund	17K	$107,001
Ashton Thomas Private Wealth, LLC	14K	$86,265
HRT Financial LP	13K	$83,000
Cambridge Investment Research Advisors, Inc.	13K	$80,000
Abacus Wealth Partners, LLC	11K	$71,562
Stokes Family Office, LLC	10K	$64,488

Who holds the shares

13F holdings at June 30, 2026

Institutions reporting: 161
Ten largest holders: 57.6%
Index fund managers: 28.1%
Active managers and hedge funds: 36.6%

Buying and selling by type of institution, March 31, 2026 to June 30, 2026
Type	Bought	Sold	New	Sold out	Net change in shares	Net %
Active managers and hedge funds	15	14	4	4	+386	0.0%
Index fund managers	10	0	1	0	+727K	+7.2%
Other institutions	56	52	16	11	+109K	+0.8%

Active managers and hedge funds: a list we maintain of about 400 well-known stock-picking firms and hedge funds, matched by SEC registration number (CIK) and checked against the filer names each quarter. Index fund managers: the large index houses, such as BlackRock, Vanguard, State Street, Geode and Northern Trust. Every other filer (banks, brokers, wealth managers, pension funds, insurers and firms not on the list) counts as another institution. A firm that files under several SEC registrations appears once for each.

What these filings can and cannot tell you

Form 13F lists the long positions in US-listed shares held by investment managers with more than $100 million in such holdings. Managers file it up to 45 days after each quarter ends, so this page shows what funds held at the end of each quarter, not what they are doing now: a position may have changed since. Short positions, most derivatives and smaller managers are not included, and a cut can mean a fund lost clients or rebalanced rather than a view on Puma Biotechnology.

Only managers that filed a holdings report for both quarters are compared (174 here). 5 other holders are left out: first-time or late filers, firms that changed their SEC registration, and filings that withheld positions under confidential treatment, any of which would otherwise look like a new position or a sale. Figures are as reported by each manager in the SEC's quarterly 13F data sets; option positions are excluded.

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