Protalix Biotherapeutics, Inc.: which funds bought and sold

Institutions that bought and sold Protalix Biotherapeutics shares in Q2 2026, from the holdings they reported to the SEC on Form 13F for March 31, 2026 and June 30, 2026.

Between March 31, 2026 and June 30, 2026, 57 institutions that filed 13F reports for both quarters added to or opened positions in Protalix Biotherapeutics, and 33 cut or closed them. Together they sold a net 2.4M shares, −14.2% on what they held at the start of the quarter. Active managers and hedge funds on our list were net buyers of 1.2M shares (+74.1%); index fund managers were net buyers of 688K shares (+9.8%). 19 opened a new position and 16 sold out entirely.

Bought, Q2 2026 57 institutions, 19 of them new holders Sold, Q2 2026 33 institutions, 16 of them sold out

Net change, all compared −2.4M shares (−14.2%)

Net change, active managers +1.2M shares (+74.1%), 12 bought, 3 sold

Buyers versus sellers

institutions compared, 118

57 bought 28 33 sold

Active managers and hedge funds 12 bought · 3 sold · +1.2M

Index fund managers 8 bought · 1 sold · +688K

Other institutions 37 bought · 29 sold · −4.3M

Biggest buyers

by change in shares held

Biggest buyers
Institution	Change in shares	Shares June 30, 2026	Value
Marshall Wace, LLP Hedge fund	+453K New position	453K	$1.1M
Blackrock, Inc. Index funds	+430K +11.9%	4.0M	$9.4M
Citadel Advisors LLC Hedge fund	+334K New position	334K	$778,749
Strs Ohio	+296K New position	296K	$689,913
Goldman Sachs Group Inc	+225K +89.4%	476K	$1.1M
Dimensional Fund Advisors LP	+197K +66.2%	493K	$1.1M
Hillsdale Investment Management Inc.	+186K New position	186K	$432,707
Millennium Management LLC Hedge fund	+172K New position	172K	$399,677
AQR Capital Management LLC Hedge fund	+137K +450.4%	168K	$391,035
Geode Capital Management, LLC Index funds	+115K +13.3%	980K	$2.3M
Jpmorgan Chase & Co	+101K +319.7%	133K	$312,529
Lazard Asset Management LLC Active manager	+79K +91.1%	166K	$385,757
Vanguard Portfolio Management LLC Index funds	+78K +18.1%	511K	$1.2M
Bailard, Inc.	+61K New position	61K	$142,363
State Of Wyoming	+59K New position	59K	$137,887
Winton Group Ltd Hedge fund	+56K New position	56K	$130,482
Franklin Resources Inc Active manager	+41K New position	41K	$96,262
Wells Fargo & Company	+41K +154.7%	68K	$157,389
Northern Trust Corp Index funds	+37K +4.2%	922K	$2.1M
Citigroup Inc	+32K +1072.7%	35K	$80,825

Biggest buyers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Marshall Wace, LLP Hedge fund	+453K New position	453K	$1.1M
Citadel Advisors LLC Hedge fund	+334K New position	334K	$778,749
Millennium Management LLC Hedge fund	+172K New position	172K	$399,677
AQR Capital Management LLC Hedge fund	+137K +450.4%	168K	$391,035
Lazard Asset Management LLC Active manager	+79K +91.1%	166K	$385,757
Winton Group Ltd Hedge fund	+56K New position	56K	$130,482
Franklin Resources Inc Active manager	+41K New position	41K	$96,262
Point72 Asset Management, L.P. Hedge fund	+26K New position	26K	$59,569
Two Sigma Investments, LP Hedge fund	+24K +134.5%	43K	$99,060
Walleye Capital LLC Hedge fund	+20K New position	20K	$46,225

Biggest sellers

by change in shares held

Biggest sellers
Institution	Change in shares	Shares June 30, 2026	Value
Mak Capital One LLC	−3.5M Sold out	0	—
Prospera Financial Services Inc	−419K Sold out	0	—
Opaleye Management Inc.	−340K Sold out	0	—
Morgan Stanley	−250K −82.9%	52K	$120,405
Connor, Clark & Lunn Investment Management Ltd.	−207K Sold out	0	—
Round Rock Advisors LLC	−192K Sold out	0	—
Evergreen Capital Management LLC	−171K Sold out	0	—
Renaissance Technologies LLC Hedge fund	−129K −10.5%	1.1M	$2.6M
UBS Group AG	−127K −47.8%	139K	$323,045
Diametric Capital, LP	−124K Sold out	0	—
Virtu Financial LLC	−68K Sold out	0	—
Orin Green Financial, LLC	−54K −84.5%	10K	$23,300
Bank Of America Corp	−27K −34.4%	52K	$120,918
Manufacturers Life Insurance Company, The	−20K Sold out	0	—
Invesco Ltd.	−11K −22.5%	37K	$85,548
Proshare Advisors LLC Index funds	−11K Sold out	0	—
LPL Financial LLC	−10K Sold out	0	—
Baader Bank Aktiengesellschaft	−10K Sold out	0	—
Susquehanna International Group, LLP	−8,141 −16.6%	41K	$95,400
Group One Trading LLC	−5,350 −40.5%	7,872	$18,342

Biggest sellers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Renaissance Technologies LLC Hedge fund	−129K −10.5%	1.1M	$2.6M
Intech Investment Management LLC Active manager	−3,512 −17.6%	16K	$38,319
Neuberger Berman Group LLC Active manager	−49 −0.4%	12K	$26,981

New positions

largest by value

Institution	Shares	Value June 30, 2026
Marshall Wace, LLPHedge fund	453K	$1.1M
Citadel Advisors LLCHedge fund	334K	$778,749
Strs Ohio	296K	$689,913
Hillsdale Investment Management Inc.	186K	$432,707
Millennium Management LLCHedge fund	172K	$399,677
Bailard, Inc.	61K	$142,363
State Of Wyoming	59K	$137,887
Winton Group LtdHedge fund	56K	$130,482
Franklin Resources IncActive manager	41K	$96,262
Point72 Asset Management, L.P.Hedge fund	26K	$59,569

Sold out

largest by value

Institution	Shares	Value March 31, 2026
Mak Capital One LLC	3.5M	$7.7M
Prospera Financial Services Inc	419K	$908,272
Opaleye Management Inc.	340K	$737,800
Connor, Clark & Lunn Investment Management Ltd.	207K	$449,787
Round Rock Advisors LLC	192K	$416,814
Evergreen Capital Management LLC	171K	$371,804
Diametric Capital, LP	124K	$269,503
Virtu Financial LLC	68K	$147,000
Manufacturers Life Insurance Company, The	20K	$42,376
Proshare Advisors LLCIndex funds	11K	$22,979

Who holds the shares

13F holdings at June 30, 2026

Institutions reporting: 102
Ten largest holders: 72.3%
Index fund managers: 53.5%
Active managers and hedge funds: 19.9%

Buying and selling by type of institution, March 31, 2026 to June 30, 2026
Type	Bought	Sold	New	Sold out	Net change in shares	Net %
Active managers and hedge funds	12	3	7	0	+1.2M	+74.1%
Index fund managers	8	1	0	1	+688K	+9.8%
Other institutions	37	29	12	15	−4.3M	−52.8%

Active managers and hedge funds: a list we maintain of about 400 well-known stock-picking firms and hedge funds, matched by SEC registration number (CIK) and checked against the filer names each quarter. Index fund managers: the large index houses, such as BlackRock, Vanguard, State Street, Geode and Northern Trust. Every other filer (banks, brokers, wealth managers, pension funds, insurers and firms not on the list) counts as another institution. A firm that files under several SEC registrations appears once for each.

What these filings can and cannot tell you

Form 13F lists the long positions in US-listed shares held by investment managers with more than $100 million in such holdings. Managers file it up to 45 days after each quarter ends, so this page shows what funds held at the end of each quarter, not what they are doing now: a position may have changed since. Short positions, most derivatives and smaller managers are not included, and a cut can mean a fund lost clients or rebalanced rather than a view on Protalix Biotherapeutics.

Only managers that filed a holdings report for both quarters are compared (118 here). 1 other holder is left out: first-time or late filers, firms that changed their SEC registration, and filings that withheld positions under confidential treatment, any of which would otherwise look like a new position or a sale. Figures are as reported by each manager in the SEC's quarterly 13F data sets; option positions are excluded.

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