undamentalytics Newsletter

Praxis Precision Medicines, Inc.: which funds bought and sold

Institutions that bought and sold Praxis Precision Medicines shares in Q2 2026, from the holdings they reported to the SEC on Form 13F for March 31, 2026 and June 30, 2026.

Between March 31, 2026 and June 30, 2026, 177 institutions that filed 13F reports for both quarters added to or opened positions in Praxis Precision Medicines, and 131 cut or closed them. Together they added a net 1.6M shares, +5.5% on what they held at the start of the quarter. Active managers and hedge funds on our list were net buyers of 86K shares (+0.6%); index fund managers were net buyers of 829K shares (+12.8%). 56 opened a new position and 38 sold out entirely.

Bought, Q2 2026 177 institutions, 56 of them new holders Sold, Q2 2026 131 institutions, 38 of them sold out
Net change, all compared +1.6M shares (+5.5%)
Net change, active managers +86K shares (+0.6%), 40 bought, 19 sold

Buyers versus sellers

institutions compared, 342
Active managers and hedge funds 40 bought · 19 sold · +86K
Index fund managers 7 bought · 5 sold · +829K
Other institutions 130 bought · 107 sold · +642K

Biggest buyers

by change in shares held
Biggest buyers
Institution Change in shares Shares June 30, 2026 Value
Vanguard Portfolio Management LLC Index funds +578K +76.4% 1.3M $447M
Invesco Ltd. +476K +775.5% 538K $180M
Price T Rowe Associates Inc Active manager +312K +49.5% 943K $316M
Polar Capital Holdings PLC Active manager +279K New position 279K $93.5M
Westfield Capital Management Co LP Active manager +218K +32966.2% 219K $73.3M
Adage Capital Partners Gp, L.L.C. Hedge fund +200K +24.5% 1.0M $340M
FMR LLC Active manager +156K +7.2% 2.3M $776M
State Street Corp Index funds +142K +16.1% 1.0M $344M
American Century Companies Inc Active manager +109K +85.0% 237K $79.5M
Massachusetts Financial Services Co Active manager +100K +1353.8% 107K $36M
Geode Capital Management, LLC Index funds +97K +14.9% 748K $250M
Voya Investment Management LLC +94K +334.4% 122K $40.9M
Marshall Wace, LLP Hedge fund +92K +203.5% 137K $45.9M
ADAR1 Capital Management, LLC Hedge fund +73K +4850.2% 74K $24.9M
Hood River Capital Management LLC +67K +18.6% 425K $142M
Neuberger Berman Group LLC Active manager +64K +244.6% 89K $30M
Orbimed Advisors LLC +58K +33.4% 230K $77M
Healthcare Of Ontario Pension Plan Trust Fund +57K New position 57K $19M
Raymond James Financial Inc +57K +1065.0% 62K $20.8M
Franklin Resources Inc Active manager +51K +18.5% 327K $110M

Biggest sellers

by change in shares held
Biggest sellers
Institution Change in shares Shares June 30, 2026 Value
Orbis Allan Gray Ltd Active manager −943K −38.1% 1.5M $512M
RA Capital Management, L.P. Hedge fund −374K Sold out 0 —
Cormorant Asset Management, LP Hedge fund −246K −27.7% 640K $214M
Goldman Sachs Group Inc −162K −22.8% 549K $184M
Soleus Capital Management, L.P. Hedge fund −153K −46.3% 178K $59.4M
Stempoint Capital LP −75K −66.9% 37K $12.5M
Arrowmark Colorado Holdings LLC −72K −60.9% 46K $15.4M
Vivo Capital, LLC −68K −20.0% 271K $90.8M
Sofinnova Investments, Inc. −57K −89.9% 6,440 $2.2M
Wellington Management Group LLP Active manager −48K −27.8% 126K $42.1M
Canada Pension Plan Investment Board −40K Sold out 0 —
Jpmorgan Chase & Co −36K −45.0% 44K $15.8M
Ally Bridge Group (NY) LLC −33K Sold out 0 —
Blackrock, Inc. Index funds −32K −1.4% 2.3M $768M
Logos Global Management LP Hedge fund −25K −8.8% 260K $87M
Congress Asset Management Co Active manager −25K Sold out 0 —
Informed Momentum Co LLC −19K Sold out 0 —
Exome Asset Management LLC −18K −40.2% 27K $9.1M
First Trust Advisors LP −17K −51.7% 16K $5.4M
Summittx Capital, L.P. −17K −46.3% 20K $6.6M

New positions

largest by value
InstitutionSharesValue June 30, 2026
Polar Capital Holdings PLCActive manager 279K $93.5M
Healthcare Of Ontario Pension Plan Trust Fund 57K $19M
SEB Asset Management AB 43K $14.3M
Clearbridge Investments, LLCActive manager 28K $9.4M
Capital Fund Management S.A.Hedge fund 27K $9.1M
WCM Investment Management, LLCActive manager 25K $8.7M
Peregrine Capital Management LLC 26K $8.6M
Castleark Management LLC 24K $8.2M
Atika Capital Management LLC 13K $4.3M
Readystate Asset Management LP 11K $3.5M

Sold out

largest by value
InstitutionSharesValue March 31, 2026
RA Capital Management, L.P.Hedge fund 374K $120M
Canada Pension Plan Investment Board 40K $12.9M
Ally Bridge Group (NY) LLC 33K $10.6M
Congress Asset Management CoActive manager 25K $8M
Informed Momentum Co LLC 19K $6.1M
Tetragon Partners Gp Ltd 16K $5.1M
Exoduspoint Capital Management, LPHedge fund 15K $4.7M
Braidwell LPHedge fund 9,976 $3.2M
Prelude Capital Management, LLC 9,064 $2.9M
Trexquant Investment LPHedge fund 6,626 $2.1M

Who holds the shares

13F holdings at June 30, 2026
Institutions reporting
308
Ten largest holders
53.3%
of 13F-reported shares
Index fund managers
21.8%
of 13F-reported shares
Active managers and hedge funds
45.7%
of 13F-reported shares
Buying and selling by type of institution, March 31, 2026 to June 30, 2026
TypeBoughtSoldNewSold outNet change in sharesNet %
Active managers and hedge funds 40 19 15 8 +86K +0.6%
Index fund managers 7 5 0 0 +829K +12.8%
Other institutions 130 107 41 30 +642K +9.8%

Active managers and hedge funds: a list we maintain of about 400 well-known stock-picking firms and hedge funds, matched by SEC registration number (CIK) and checked against the filer names each quarter. Index fund managers: the large index houses, such as BlackRock, Vanguard, State Street, Geode and Northern Trust. Every other filer (banks, brokers, wealth managers, pension funds, insurers and firms not on the list) counts as another institution. A firm that files under several SEC registrations appears once for each.

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