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Protagonist Therapeutics, Inc: which funds bought and sold

Institutions that bought and sold Protagonist Therapeutics shares in Q2 2026, from the holdings they reported to the SEC on Form 13F for March 31, 2026 and June 30, 2026.

Between March 31, 2026 and June 30, 2026, 198 institutions that filed 13F reports for both quarters added to or opened positions in Protagonist Therapeutics, and 124 cut or closed them. Together they sold a net 2.3M shares, −3.0% on what they held at the start of the quarter. Active managers and hedge funds on our list were net sellers of 2.2M shares (−7.4%); index fund managers were net buyers of 1.1M shares (+4.8%). 58 opened a new position and 36 sold out entirely.

Bought, Q2 2026 198 institutions, 58 of them new holders Sold, Q2 2026 124 institutions, 36 of them sold out
Net change, all compared −2.3M shares (−3.0%)
Net change, active managers −2.2M shares (−7.4%), 31 bought, 24 sold

Buyers versus sellers

institutions compared, 374
Active managers and hedge funds 31 bought · 24 sold · −2.2M
Index fund managers 9 bought · 3 sold · +1.1M
Other institutions 158 bought · 97 sold · −1.1M

Biggest buyers

by change in shares held
Biggest buyers
Institution Change in shares Shares June 30, 2026 Value
Blackrock, Inc. Index funds +528K +5.4% 10.3M $1.3B
Price T Rowe Associates Inc Active manager +484K +29.1% 2.1M $264M
Franklin Resources Inc Active manager +382K +277.2% 520K $63.7M
Alyeska Investment Group, L.P. Hedge fund +296K +49.9% 889K $109M
Stephens Investment Management Group LLC +282K New position 282K $34.5M
Lord, Abbett & Co. LLC +236K +144.1% 399K $48.9M
State Street Corp Index funds +205K +6.6% 3.3M $407M
Invesco Ltd. +176K +8.1% 2.3M $287M
Neuberger Berman Group LLC Active manager +161K +113.8% 302K $37.1M
Nuveen, LLC +156K +122.1% 284K $34.8M
Vanguard Portfolio Management LLC Index funds +148K +4.3% 3.6M $445M
Nomura Asset Management International Inc. +141K New position 141K $17.3M
Voya Investment Management LLC +117K +25.8% 572K $70.1M
BNP Paribas Financial Markets +107K +55.0% 301K $37M
Catalio Capital Management, LP +107K New position 107K $13.1M
Clearbridge Investments, LLC Active manager +104K +16.6% 725K $88.9M
Jennison Associates LLC Active manager +80K +7.4% 1.2M $141M
Northern Trust Corp Index funds +78K +13.3% 666K $81.7M
Russell Investments Group, Ltd. +75K +185.9% 115K $14.1M
Geode Capital Management, LLC Index funds +72K +4.3% 1.7M $213M

Biggest sellers

by change in shares held
Biggest sellers
Institution Change in shares Shares June 30, 2026 Value
UBS Group AG −1.8M −34.4% 3.4M $417M
Citadel Advisors LLC Hedge fund −1.6M Sold out 0 —
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. −572K Sold out 0 —
Marshall Wace, LLP Hedge fund −519K −82.6% 109K $13.4M
Rubric Capital Management LP Hedge fund −428K Sold out 0 —
Dimensional Fund Advisors LP −330K −64.9% 178K $21.8M
Vestal Point Capital, LP Hedge fund −326K Sold out 0 —
Adage Capital Partners Gp, L.L.C. Hedge fund −282K Sold out 0 —
Perceptive Advisors LLC Hedge fund −249K −20.2% 982K $120M
Holocene Advisors, LP Hedge fund −201K −96.0% 8,495 $1M
Wellington Management Group LLP Active manager −183K −5.1% 3.4M $419M
Stempoint Capital LP −129K −88.8% 16K $2M
Morgan Stanley −112K −11.0% 906K $111M
Panagora Asset Management Inc Active manager −111K −95.0% 5,832 $714,887
Susquehanna International Group, LLP −111K −65.9% 57K $7M
Balyasny Asset Management L.P. Hedge fund −98K −96.4% 3,598 $441,043
683 Capital Management, LLC Hedge fund −65K −18.3% 290K $35.5M
Integral Health Asset Management, LLC −50K Sold out 0 —
TD Asset Management Inc −49K −26.5% 135K $16.5M
BNP Paribas Asset Management Holding S.A. −46K −15.1% 260K $31.9M

New positions

largest by value

Sold out

largest by value
InstitutionSharesValue March 31, 2026
Citadel Advisors LLCHedge fund 1.6M $164M
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. 572K $60.3M
Rubric Capital Management LPHedge fund 428K $45.1M
Vestal Point Capital, LPHedge fund 326K $34.4M
Adage Capital Partners Gp, L.L.C.Hedge fund 282K $29.8M
Integral Health Asset Management, LLC 50K $5.3M
Royce & Associates LPActive manager 14K $1.5M
Hussman Strategic Advisors, Inc. 11K $1.1M
Nomura Holdings Inc 10K $1.1M
Advisors Asset Management, Inc. 4,644 $489,478

Who holds the shares

13F holdings at June 30, 2026
Institutions reporting
342
Ten largest holders
56.9%
of 13F-reported shares
Index fund managers
31.3%
of 13F-reported shares
Active managers and hedge funds
36.9%
of 13F-reported shares
Buying and selling by type of institution, March 31, 2026 to June 30, 2026
TypeBoughtSoldNewSold outNet change in sharesNet %
Active managers and hedge funds 31 24 10 7 −2.2M −7.4%
Index fund managers 9 3 0 0 +1.1M +4.8%
Other institutions 158 97 48 29 −1.1M −5.0%

Active managers and hedge funds: a list we maintain of about 400 well-known stock-picking firms and hedge funds, matched by SEC registration number (CIK) and checked against the filer names each quarter. Index fund managers: the large index houses, such as BlackRock, Vanguard, State Street, Geode and Northern Trust. Every other filer (banks, brokers, wealth managers, pension funds, insurers and firms not on the list) counts as another institution. A firm that files under several SEC registrations appears once for each.

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