Q32 Bio Inc.: which funds bought and sold

Institutions that bought and sold Q32 Bio shares in Q2 2026, from the holdings they reported to the SEC on Form 13F for March 31, 2026 and June 30, 2026.

Between March 31, 2026 and June 30, 2026, 45 institutions that filed 13F reports for both quarters added to or opened positions in Q32 Bio, and 21 cut or closed them. Together they added a net 12.8M shares, +135.4% on what they held at the start of the quarter. Active managers and hedge funds on our list were net buyers of 8.4M shares (+1490.5%); index fund managers were net buyers of 275K shares (+43.8%). 27 opened a new position and 9 sold out entirely.

Bought, Q2 2026 45 institutions, 27 of them new holders Sold, Q2 2026 21 institutions, 9 of them sold out

Net change, all compared +12.8M shares (+135.4%)

Net change, active managers +8.4M shares (+1490.5%), 18 bought, 4 sold

Buyers versus sellers

institutions compared, 79

45 bought 13 21 sold

Active managers and hedge funds 18 bought · 4 sold · +8.4M

Index fund managers 5 bought · 1 sold · +275K

Other institutions 22 bought · 16 sold · +4.1M

Biggest buyers

by change in shares held

Biggest buyers
Institution	Change in shares	Shares June 30, 2026	Value
Boxer Capital Management, LLC Hedge fund	+3.1M New position	3.1M	$40.1M
Bvf Inc	+2.4M New position	2.4M	$29.9M
RA Capital Management, L.P. Hedge fund	+2.3M New position	2.3M	$29.7M
Orbimed Advisors LLC	+1.9M +83.2%	4.1M	$52.6M
Point72 Asset Management, L.P. Hedge fund	+1.2M New position	1.2M	$14.9M
Logos Global Management LP Hedge fund	+800K New position	800K	$10.2M
Summittx Capital, L.P.	+734K New position	734K	$9.3M
Atlas Venture Life Science Advisors, LLC	+625K +29.9%	2.7M	$34.6M
Ikarian Capital, LLC	+430K New position	430K	$5.5M
Woodline Partners LP Hedge fund	+286K New position	286K	$3.6M
American Century Companies Inc Active manager	+254K +1353.1%	273K	$3.5M
Vanguard Capital Management LLC Index funds	+212K +69.3%	519K	$6.6M
Boothbay Fund Management, LLC Hedge fund	+130K New position	130K	$1.7M
Citadel Advisors LLC Hedge fund	+105K +679.4%	121K	$1.5M
Jane Street Group, LLC	+97K +148.1%	163K	$2.1M
Acadian Asset Management LLC Active manager	+46K +26.4%	218K	$2.8M
Quadrature Capital Ltd Hedge fund	+36K New position	36K	$463,685
Dafna Capital Management LLC	+33K New position	33K	$419,095
Blackrock, Inc. Index funds	+32K +37.6%	119K	$1.5M
Knott David M Jr	+30K New position	30K	$387,449

Biggest buyers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Boxer Capital Management, LLC Hedge fund	+3.1M New position	3.1M	$40.1M
RA Capital Management, L.P. Hedge fund	+2.3M New position	2.3M	$29.7M
Point72 Asset Management, L.P. Hedge fund	+1.2M New position	1.2M	$14.9M
Logos Global Management LP Hedge fund	+800K New position	800K	$10.2M
Woodline Partners LP Hedge fund	+286K New position	286K	$3.6M
American Century Companies Inc Active manager	+254K +1353.1%	273K	$3.5M
Boothbay Fund Management, LLC Hedge fund	+130K New position	130K	$1.7M
Citadel Advisors LLC Hedge fund	+105K +679.4%	121K	$1.5M
Acadian Asset Management LLC Active manager	+46K +26.4%	218K	$2.8M
Quadrature Capital Ltd Hedge fund	+36K New position	36K	$463,685

Biggest sellers

by change in shares held

Biggest sellers
Institution	Change in shares	Shares June 30, 2026	Value
Carlyle Group Inc.	−1.0M −94.5%	60K	$769,020
Opaleye Management Inc.	−325K −25.9%	931K	$11.9M
Arch Venture Management, LLC	−320K Sold out	0	—
Mackenzie Financial Corp	−246K Sold out	0	—
Pfizer Inc	−102K Sold out	0	—
Acorn Capital Advisors, LLC	−99K −31.4%	216K	$2.8M
ADAR1 Capital Management, LLC Hedge fund	−35K Sold out	0	—
Renaissance Technologies LLC Hedge fund	−27K −13.2%	180K	$2.3M
Cetera Investment Advisers	−21K Sold out	0	—
Eversource Wealth Advisors, LLC	−4,400 −94.8%	240	$3,058
Morgan Stanley	−3,104 −32.5%	6,456	$82,259
Royal Bank Of Canada	−2,733 Sold out	0	—
Monimus Capital Management, LP	−2,274 −1.7%	132K	$1.7M
Tower Research Capital LLC (TRC)	−1,871 Sold out	0	—
Northern Trust Corp Index funds	−1,402 −5.6%	24K	$301,059
Federated Hermes, Inc. Active manager	−1,223 −53.8%	1,050	$13,377
Northwestern Mutual Wealth Management Co	−111 Sold out	0	—
Wells Fargo & Company	−84 Sold out	0	—
Arax Advisory Partners	−37 −3.2%	1,111	$14,154
FMR LLC Active manager	−12 −0.4%	3,388	$43,163

Biggest sellers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
ADAR1 Capital Management, LLC Hedge fund	−35K Sold out	0	—
Renaissance Technologies LLC Hedge fund	−27K −13.2%	180K	$2.3M
Federated Hermes, Inc. Active manager	−1,223 −53.8%	1,050	$13,377
FMR LLC Active manager	−12 −0.4%	3,388	$43,163

New positions

largest by value

Institution	Shares	Value June 30, 2026
Boxer Capital Management, LLCHedge fund	3.1M	$40.1M
Bvf Inc	2.4M	$29.9M
RA Capital Management, L.P.Hedge fund	2.3M	$29.7M
Point72 Asset Management, L.P.Hedge fund	1.2M	$14.9M
Logos Global Management LPHedge fund	800K	$10.2M
Summittx Capital, L.P.	734K	$9.3M
Ikarian Capital, LLC	430K	$5.5M
Woodline Partners LPHedge fund	286K	$3.6M
Boothbay Fund Management, LLCHedge fund	130K	$1.7M
Quadrature Capital LtdHedge fund	36K	$463,685

Sold out

largest by value

Institution	Shares	Value March 31, 2026
Arch Venture Management, LLC	320K	$2.1M
Mackenzie Financial Corp	246K	$1.6M
Pfizer Inc	102K	$736,731
ADAR1 Capital Management, LLCHedge fund	35K	$224,700
Cetera Investment Advisers	21K	$132,862
Royal Bank Of Canada	2,733	$18,000
Tower Research Capital LLC (TRC)	1,871	$12,012
Northwestern Mutual Wealth Management Co	111	$713
Wells Fargo & Company	84	$539

Who holds the shares

13F holdings at June 30, 2026

Institutions reporting: 70
Ten largest holders: 84.8%
Index fund managers: 4.1%
Active managers and hedge funds: 40.3%

Buying and selling by type of institution, March 31, 2026 to June 30, 2026
Type	Bought	Sold	New	Sold out	Net change in shares	Net %
Active managers and hedge funds	18	4	12	1	+8.4M	+1490.5%
Index fund managers	5	1	0	0	+275K	+43.8%
Other institutions	22	16	15	8	+4.1M	+50.0%

Active managers and hedge funds: a list we maintain of about 400 well-known stock-picking firms and hedge funds, matched by SEC registration number (CIK) and checked against the filer names each quarter. Index fund managers: the large index houses, such as BlackRock, Vanguard, State Street, Geode and Northern Trust. Every other filer (banks, brokers, wealth managers, pension funds, insurers and firms not on the list) counts as another institution. A firm that files under several SEC registrations appears once for each.

What these filings can and cannot tell you

Form 13F lists the long positions in US-listed shares held by investment managers with more than $100 million in such holdings. Managers file it up to 45 days after each quarter ends, so this page shows what funds held at the end of each quarter, not what they are doing now: a position may have changed since. Short positions, most derivatives and smaller managers are not included, and a cut can mean a fund lost clients or rebalanced rather than a view on Q32 Bio.

Only managers that filed a holdings report for both quarters are compared (79 here). 1 other holder is left out: first-time or late filers, firms that changed their SEC registration, and filings that withheld positions under confidential treatment, any of which would otherwise look like a new position or a sale. Figures are as reported by each manager in the SEC's quarterly 13F data sets; option positions are excluded.

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