undamentalytics Newsletter

Spruce Biosciences, Inc.: which funds bought and sold

Institutions that bought and sold Spruce Biosciences shares in Q2 2026, from the holdings they reported to the SEC on Form 13F for March 31, 2026 and June 30, 2026.

Between March 31, 2026 and June 30, 2026, 51 institutions that filed 13F reports for both quarters added to or opened positions in Spruce Biosciences, and 7 cut or closed them. Together they added a net 1.3M shares, +168.4% on what they held at the start of the quarter. Active managers and hedge funds on our list were net buyers of 127K shares (+28.5%); index fund managers were net buyers of 436K shares (+738.8%). 35 opened a new position and 4 sold out entirely.

Bought, Q2 2026 51 institutions, 35 of them new holders Sold, Q2 2026 7 institutions, 4 of them sold out
Net change, all compared +1.3M shares (+168.4%)
Net change, active managers +127K shares (+28.5%), 8 bought, 3 sold

Buyers versus sellers

institutions compared, 67
Active managers and hedge funds 8 bought · 3 sold · +127K
Index fund managers 9 bought · 0 sold · +436K
Other institutions 34 bought · 4 sold · +694K

Biggest buyers

by change in shares held
Biggest buyers
Institution Change in shares Shares June 30, 2026 Value
Aigh Capital Management LLC +250K New position 250K $13.5M
Orbimed Advisors LLC +200K New position 200K $10.8M
Blackrock, Inc. Index funds +171K +1009.0% 188K $10.1M
Vanguard Capital Management LLC Index funds +101K +550.8% 119K $6.4M
Cable Car Capital, LP Hedge fund +60K New position 60K $3.2M
Geode Capital Management, LLC Index funds +58K +447.4% 71K $3.8M
Millennium Management LLC Hedge fund +49K +43.9% 161K $8.7M
State Street Corp Index funds +45K +834.3% 50K $2.7M
Eversept Partners, LP Hedge fund +40K New position 40K $2.2M
Affinity Asset Advisors, LLC +30K New position 30K $1.6M
Alyeska Investment Group, L.P. Hedge fund +30K +58.1% 82K $4.4M
Stonepine Capital Management, LLC +29K New position 29K $1.6M
Stempoint Capital LP +29K +225.4% 41K $2.2M
Point72 Asset Management, L.P. Hedge fund +28K New position 28K $1.5M
Goldman Sachs Group Inc +27K +487.5% 32K $1.7M
Northern Trust Corp Index funds +21K New position 21K $1.1M
Diadema Partners LP +20K +200.0% 30K $1.6M
Knott David M Jr +20K New position 20K $1.1M
Rosalind Advisors, Inc. +20K New position 20K $1.1M
UBS Group AG +19K +496.6% 23K $1.3M

Biggest sellers

by change in shares held
Biggest sellers
Institution Change in shares Shares June 30, 2026 Value
Wellington Management Group LLP Active manager −49K Sold out 0 —
Balyasny Asset Management L.P. Hedge fund −28K −69.7% 12K $655,452
Citadel Advisors LLC Hedge fund −18K −25.8% 52K $2.8M
Squadron Capital Management LLC −12K Sold out 0 —
Resolute Capital Asset Partners LLC −4,000 Sold out 0 —
Sound Income Strategies, LLC −200 Sold out 0 —
Jones Financial Companies LLLP −163 −84.5% 30 $1,653

New positions

largest by value
InstitutionSharesValue June 30, 2026
Aigh Capital Management LLC 250K $13.5M
Orbimed Advisors LLC 200K $10.8M
Cable Car Capital, LPHedge fund 60K $3.2M
Eversept Partners, LPHedge fund 40K $2.2M
Affinity Asset Advisors, LLC 30K $1.6M
Stonepine Capital Management, LLC 29K $1.6M
Point72 Asset Management, L.P.Hedge fund 28K $1.5M
Northern Trust CorpIndex funds 21K $1.1M
Knott David M Jr 20K $1.1M
Rosalind Advisors, Inc. 20K $1.1M

Sold out

largest by value
InstitutionSharesValue March 31, 2026
Wellington Management Group LLPActive manager 49K $3.2M
Squadron Capital Management LLC 12K $797,270
Resolute Capital Asset Partners LLC 4,000 $261,400
Sound Income Strategies, LLC 200 $13,906

Who holds the shares

13F holdings at June 30, 2026
Institutions reporting
63
Ten largest holders
65.9%
of 13F-reported shares
Index fund managers
24.7%
of 13F-reported shares
Active managers and hedge funds
28.5%
of 13F-reported shares
Buying and selling by type of institution, March 31, 2026 to June 30, 2026
TypeBoughtSoldNewSold outNet change in sharesNet %
Active managers and hedge funds 8 3 5 1 +127K +28.5%
Index fund managers 9 0 4 0 +436K +738.8%
Other institutions 34 4 26 3 +694K +286.6%

Active managers and hedge funds: a list we maintain of about 400 well-known stock-picking firms and hedge funds, matched by SEC registration number (CIK) and checked against the filer names each quarter. Index fund managers: the large index houses, such as BlackRock, Vanguard, State Street, Geode and Northern Trust. Every other filer (banks, brokers, wealth managers, pension funds, insurers and firms not on the list) counts as another institution. A firm that files under several SEC registrations appears once for each.

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