Spruce Biosciences, Inc.: which funds bought and sold
Institutions that bought and sold Spruce Biosciences shares in Q2 2026, from the holdings they reported to the SEC on Form 13F for March 31, 2026 and June 30, 2026.
Between March 31, 2026 and June 30, 2026, 51 institutions that filed 13F reports for both quarters added to or opened positions in Spruce Biosciences, and 7 cut or closed them. Together they added a net 1.3M shares, +168.4% on what they held at the start of the quarter. Active managers and hedge funds on our list were net buyers of 127K shares (+28.5%); index fund managers were net buyers of 436K shares (+738.8%). 35 opened a new position and 4 sold out entirely.
Bought, Q2 2026 51 institutions, 35 of them new holders Sold, Q2 2026 7 institutions, 4 of them sold out
Net change, all compared +1.3M shares (+168.4%)
Net change, active managers +127K shares (+28.5%), 8 bought, 3 sold
Buyers versus sellers
51 bought 9 7 sold
Active managers and hedge funds 8 bought · 3 sold · +127K
Index fund managers 9 bought · 0 sold · +436K
Other institutions 34 bought · 4 sold · +694K
Biggest buyers
| Institution | Change in shares | Shares June 30, 2026 | Value |
|---|---|---|---|
| Aigh Capital Management LLC | +250K New position | 250K | $13.5M |
| Orbimed Advisors LLC | +200K New position | 200K | $10.8M |
| Blackrock, Inc. Index funds | +171K +1009.0% | 188K | $10.1M |
| Vanguard Capital Management LLC Index funds | +101K +550.8% | 119K | $6.4M |
| Cable Car Capital, LP Hedge fund | +60K New position | 60K | $3.2M |
| Geode Capital Management, LLC Index funds | +58K +447.4% | 71K | $3.8M |
| Millennium Management LLC Hedge fund | +49K +43.9% | 161K | $8.7M |
| State Street Corp Index funds | +45K +834.3% | 50K | $2.7M |
| Eversept Partners, LP Hedge fund | +40K New position | 40K | $2.2M |
| Affinity Asset Advisors, LLC | +30K New position | 30K | $1.6M |
| Alyeska Investment Group, L.P. Hedge fund | +30K +58.1% | 82K | $4.4M |
| Stonepine Capital Management, LLC | +29K New position | 29K | $1.6M |
| Stempoint Capital LP | +29K +225.4% | 41K | $2.2M |
| Point72 Asset Management, L.P. Hedge fund | +28K New position | 28K | $1.5M |
| Goldman Sachs Group Inc | +27K +487.5% | 32K | $1.7M |
| Northern Trust Corp Index funds | +21K New position | 21K | $1.1M |
| Diadema Partners LP | +20K +200.0% | 30K | $1.6M |
| Knott David M Jr | +20K New position | 20K | $1.1M |
| Rosalind Advisors, Inc. | +20K New position | 20K | $1.1M |
| UBS Group AG | +19K +496.6% | 23K | $1.3M |
| Institution | Change in shares | Shares June 30, 2026 | Value |
|---|---|---|---|
| Cable Car Capital, LP Hedge fund | +60K New position | 60K | $3.2M |
| Millennium Management LLC Hedge fund | +49K +43.9% | 161K | $8.7M |
| Eversept Partners, LP Hedge fund | +40K New position | 40K | $2.2M |
| Alyeska Investment Group, L.P. Hedge fund | +30K +58.1% | 82K | $4.4M |
| Point72 Asset Management, L.P. Hedge fund | +28K New position | 28K | $1.5M |
| ADAR1 Capital Management, LLC Hedge fund | +9,117 +15.6% | 68K | $3.7M |
| Renaissance Technologies LLC Hedge fund | +4,700 New position | 4,700 | $253,800 |
| FMR LLC Active manager | +343 New position | 343 | $18,522 |
Biggest sellers
| Institution | Change in shares | Shares June 30, 2026 | Value |
|---|---|---|---|
| Wellington Management Group LLP Active manager | −49K Sold out | 0 | — |
| Balyasny Asset Management L.P. Hedge fund | −28K −69.7% | 12K | $655,452 |
| Citadel Advisors LLC Hedge fund | −18K −25.8% | 52K | $2.8M |
| Squadron Capital Management LLC | −12K Sold out | 0 | — |
| Resolute Capital Asset Partners LLC | −4,000 Sold out | 0 | — |
| Sound Income Strategies, LLC | −200 Sold out | 0 | — |
| Jones Financial Companies LLLP | −163 −84.5% | 30 | $1,653 |
| Institution | Change in shares | Shares June 30, 2026 | Value |
|---|---|---|---|
| Wellington Management Group LLP Active manager | −49K Sold out | 0 | — |
| Balyasny Asset Management L.P. Hedge fund | −28K −69.7% | 12K | $655,452 |
| Citadel Advisors LLC Hedge fund | −18K −25.8% | 52K | $2.8M |
New positions
| Institution | Shares | Value June 30, 2026 |
|---|---|---|
| Aigh Capital Management LLC | 250K | $13.5M |
| Orbimed Advisors LLC | 200K | $10.8M |
| Cable Car Capital, LPHedge fund | 60K | $3.2M |
| Eversept Partners, LPHedge fund | 40K | $2.2M |
| Affinity Asset Advisors, LLC | 30K | $1.6M |
| Stonepine Capital Management, LLC | 29K | $1.6M |
| Point72 Asset Management, L.P.Hedge fund | 28K | $1.5M |
| Northern Trust CorpIndex funds | 21K | $1.1M |
| Knott David M Jr | 20K | $1.1M |
| Rosalind Advisors, Inc. | 20K | $1.1M |
Sold out
| Institution | Shares | Value March 31, 2026 |
|---|---|---|
| Wellington Management Group LLPActive manager | 49K | $3.2M |
| Squadron Capital Management LLC | 12K | $797,270 |
| Resolute Capital Asset Partners LLC | 4,000 | $261,400 |
| Sound Income Strategies, LLC | 200 | $13,906 |
Who holds the shares
- Institutions reporting
- 63
- Ten largest holders
- 65.9% of 13F-reported shares
- Index fund managers
- 24.7% of 13F-reported shares
- Active managers and hedge funds
- 28.5% of 13F-reported shares
| Type | Bought | Sold | New | Sold out | Net change in shares | Net % |
|---|---|---|---|---|---|---|
| Active managers and hedge funds | 8 | 3 | 5 | 1 | +127K | +28.5% |
| Index fund managers | 9 | 0 | 4 | 0 | +436K | +738.8% |
| Other institutions | 34 | 4 | 26 | 3 | +694K | +286.6% |