Shattuck Labs, Inc.: which funds bought and sold

Institutions that bought and sold Shattuck Labs shares in Q2 2026, from the holdings they reported to the SEC on Form 13F for March 31, 2026 and June 30, 2026.

Between March 31, 2026 and June 30, 2026, 72 institutions that filed 13F reports for both quarters added to or opened positions in Shattuck Labs, and 35 cut or closed them. Together they added a net 27.6M shares, +49.3% on what they held at the start of the quarter. Active managers and hedge funds on our list were net buyers of 13.3M shares (+60.6%); index fund managers were net buyers of 7.8M shares (+185.2%). 37 opened a new position and 20 sold out entirely.

Bought, Q2 2026 72 institutions, 37 of them new holders Sold, Q2 2026 35 institutions, 20 of them sold out

Net change, all compared +27.6M shares (+49.3%)

Net change, active managers +13.3M shares (+60.6%), 15 bought, 11 sold

Buyers versus sellers

institutions compared, 119

72 bought 12 35 sold

Active managers and hedge funds 15 bought · 11 sold · +13.3M

Index fund managers 9 bought · 0 sold · +7.8M

Other institutions 48 bought · 24 sold · +6.5M

Biggest buyers

by change in shares held

Biggest buyers
Institution	Change in shares	Shares June 30, 2026	Value
Frazier Life Sciences Management, L.P.	+3.8M New position	3.8M	$26M
Deep Track Capital, LP Hedge fund	+3.7M New position	3.7M	$25.7M
T. Rowe Price Investment Management, Inc. Active manager	+3.6M +36.2%	13.4M	$93.2M
Adage Capital Partners Gp, L.L.C. Hedge fund	+3.5M +74.9%	8.1M	$56.4M
Blackrock, Inc. Index funds	+3.4M +670.5%	3.9M	$27.3M
Wellington Management Group LLP Active manager	+1.8M New position	1.8M	$12.3M
Redmile Group, LLC	+1.4M +24.4%	6.9M	$47.8M
Boxer Capital Management, LLC Hedge fund	+1.0M New position	1.0M	$6.9M
Prosight Management, LP	+953K +19.1%	6.0M	$41.3M
Vanguard Portfolio Management LLC Index funds	+947K New position	947K	$6.6M
Geode Capital Management, LLC Index funds	+939K +145.4%	1.6M	$11M
Vanguard Capital Management LLC Index funds	+931K +40.9%	3.2M	$22.3M
Price T Rowe Associates Inc Active manager	+858K +48.1%	2.6M	$18.3M
State Street Corp Index funds	+763K +289.1%	1.0M	$7.1M
Nextbio Capital Management LP	+577K +18.3%	3.7M	$25.9M
Pinnacle Associates Ltd	+503K +36.8%	1.9M	$13M
Goldman Sachs Group Inc	+402K +209.9%	593K	$4.1M
Northern Trust Corp Index funds	+394K +312.7%	520K	$3.6M
683 Capital Management, LLC Hedge fund	+357K +44.7%	1.2M	$8M
Aberdeen Group PLC	+247K +21.3%	1.4M	$9.8M

Biggest buyers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Deep Track Capital, LP Hedge fund	+3.7M New position	3.7M	$25.7M
T. Rowe Price Investment Management, Inc. Active manager	+3.6M +36.2%	13.4M	$93.2M
Adage Capital Partners Gp, L.L.C. Hedge fund	+3.5M +74.9%	8.1M	$56.4M
Wellington Management Group LLP Active manager	+1.8M New position	1.8M	$12.3M
Boxer Capital Management, LLC Hedge fund	+1.0M New position	1.0M	$6.9M
Price T Rowe Associates Inc Active manager	+858K +48.1%	2.6M	$18.3M
683 Capital Management, LLC Hedge fund	+357K +44.7%	1.2M	$8M
Point72 Asset Management, L.P. Hedge fund	+140K +13.5%	1.2M	$8.1M
Renaissance Technologies LLC Hedge fund	+139K +23.0%	744K	$5.2M
Algert Global LLC Hedge fund	+135K +47.2%	421K	$2.9M

Biggest sellers

by change in shares held

Biggest sellers
Institution	Change in shares	Shares June 30, 2026	Value
Ameriprise Financial Inc	−870K −96.1%	36K	$246,710
Susquehanna International Group, LLP	−691K −96.5%	25K	$174,721
Marshall Wace, LLP Hedge fund	−581K Sold out	0	—
Millennium Management LLC Hedge fund	−570K −74.6%	194K	$1.3M
Jane Street Group, LLC	−416K Sold out	0	—
Diadema Partners LP	−294K Sold out	0	—
Hudson Bay Capital Management LP Hedge fund	−229K Sold out	0	—
Sphera Funds Management Ltd.	−194K −69.2%	86K	$600,039
Citadel Advisors LLC Hedge fund	−148K Sold out	0	—
Two Sigma Investments, LP Hedge fund	−130K −41.2%	186K	$1.3M
Qube Research & Technologies Ltd Hedge fund	−127K Sold out	0	—
Barclays PLC	−103K −85.5%	17K	$120,575
HRT Financial LP	−91K Sold out	0	—
Brevan Howard Capital Management LP Hedge fund	−79K Sold out	0	—
Persistent Asset Partners Ltd	−74K Sold out	0	—
Xtx Topco Ltd	−49K −34.2%	94K	$650,653
American Century Companies Inc Active manager	−48K Sold out	0	—
Citigroup Inc	−46K −61.6%	29K	$199,671
Clark Estates Inc	−45K −3.1%	1.4M	$9.9M
Ep Wealth Advisors, LLC	−41K Sold out	0	—

Biggest sellers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Marshall Wace, LLP Hedge fund	−581K Sold out	0	—
Millennium Management LLC Hedge fund	−570K −74.6%	194K	$1.3M
Hudson Bay Capital Management LP Hedge fund	−229K Sold out	0	—
Citadel Advisors LLC Hedge fund	−148K Sold out	0	—
Two Sigma Investments, LP Hedge fund	−130K −41.2%	186K	$1.3M
Qube Research & Technologies Ltd Hedge fund	−127K Sold out	0	—
Brevan Howard Capital Management LP Hedge fund	−79K Sold out	0	—
American Century Companies Inc Active manager	−48K Sold out	0	—
Engineers Gate Manager LP Hedge fund	−16K Sold out	0	—
Quadrature Capital Ltd Hedge fund	−12K Sold out	0	—

New positions

largest by value

Institution	Shares	Value June 30, 2026
Frazier Life Sciences Management, L.P.	3.8M	$26M
Deep Track Capital, LPHedge fund	3.7M	$25.7M
Wellington Management Group LLPActive manager	1.8M	$12.3M
Boxer Capital Management, LLCHedge fund	1.0M	$6.9M
Vanguard Portfolio Management LLCIndex funds	947K	$6.6M
West Tower Group, LLC	192K	$1.3M
Nuveen, LLC	81K	$565,069
Rhumbline AdvisersIndex funds	71K	$496,120
Gsa Capital Partners LLP	68K	$474,000
Wells Fargo & Company	55K	$384,247

Sold out

largest by value

Institution	Shares	Value March 31, 2026
Marshall Wace, LLPHedge fund	581K	$3.7M
Jane Street Group, LLC	416K	$2.7M
Diadema Partners LP	294K	$1.9M
Hudson Bay Capital Management LPHedge fund	229K	$1.5M
Citadel Advisors LLCHedge fund	148K	$951,775
Qube Research & Technologies LtdHedge fund	127K	$815,311
HRT Financial LP	91K	$583,000
Brevan Howard Capital Management LPHedge fund	79K	$511,031
Persistent Asset Partners Ltd	74K	$477,292
American Century Companies IncActive manager	48K	$309,457

Who holds the shares

13F holdings at June 30, 2026

Institutions reporting: 100
Ten largest holders: 70.5%
Index fund managers: 14.3%
Active managers and hedge funds: 42.2%

Buying and selling by type of institution, March 31, 2026 to June 30, 2026
Type	Bought	Sold	New	Sold out	Net change in shares	Net %
Active managers and hedge funds	15	11	5	9	+13.3M	+60.6%
Index fund managers	9	0	2	0	+7.8M	+185.2%
Other institutions	48	24	30	11	+6.5M	+21.9%

Active managers and hedge funds: a list we maintain of about 400 well-known stock-picking firms and hedge funds, matched by SEC registration number (CIK) and checked against the filer names each quarter. Index fund managers: the large index houses, such as BlackRock, Vanguard, State Street, Geode and Northern Trust. Every other filer (banks, brokers, wealth managers, pension funds, insurers and firms not on the list) counts as another institution. A firm that files under several SEC registrations appears once for each.

What these filings can and cannot tell you

Form 13F lists the long positions in US-listed shares held by investment managers with more than $100 million in such holdings. Managers file it up to 45 days after each quarter ends, so this page shows what funds held at the end of each quarter, not what they are doing now: a position may have changed since. Short positions, most derivatives and smaller managers are not included, and a cut can mean a fund lost clients or rebalanced rather than a view on Shattuck Labs.

Only managers that filed a holdings report for both quarters are compared (119 here). 2 other holders are left out: first-time or late filers, firms that changed their SEC registration, and filings that withheld positions under confidential treatment, any of which would otherwise look like a new position or a sale. Figures are as reported by each manager in the SEC's quarterly 13F data sets; option positions are excluded.

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