Vertex Pharmaceuticals: which funds bought and sold

Institutions that bought and sold Vertex Pharmaceuticals shares in Q2 2026, from the holdings they reported to the SEC on Form 13F for March 31, 2026 and June 30, 2026.

Between March 31, 2026 and June 30, 2026, 870 institutions that filed 13F reports for both quarters added to or opened positions in Vertex Pharmaceuticals, and 717 cut or closed them. Together they added a net 2.2M shares, +0.9% on what they held at the start of the quarter. Active managers and hedge funds on our list were net buyers of 674K shares (+0.8%); index fund managers were net sellers of 137K shares (−0.2%). 168 opened a new position and 108 sold out entirely.

Bought, Q2 2026 870 institutions, 168 of them new holders Sold, Q2 2026 717 institutions, 108 of them sold out

Net change, all compared +2.2M shares (+0.9%)

Net change, active managers +674K shares (+0.8%), 47 bought, 49 sold

Buyers versus sellers

institutions compared, 1,821

870 bought 234 717 sold

Active managers and hedge funds 47 bought · 49 sold · +674K

Index fund managers 6 bought · 6 sold · −137K

Other institutions 817 bought · 662 sold · +1.7M

Biggest buyers

by change in shares held

Biggest buyers
Institution	Change in shares	Shares June 30, 2026	Value
Franklin Resources Inc Active manager	+2.8M +507.3%	3.3M	$1.7B
Assenagon Asset Management S.A.	+982K +182.8%	1.5M	$755M
Capital World Investors Active manager	+747K +2.9%	26.1M	$13B
SG Americas Securities, LLC	+467K +819.1%	524K	$260M
AQR Capital Management LLC Hedge fund	+445K +260.3%	616K	$305M
Millennium Management LLC Hedge fund	+438K +1419.7%	468K	$233M
Hudson Bay Capital Management LP Hedge fund	+345K +767.6%	390K	$194M
Victory Capital Management Inc Active manager	+285K +15.1%	2.2M	$1.1B
Jennison Associates LLC Active manager	+258K +9.4%	3.0M	$1.5B
Marshall Wace, LLP Hedge fund	+227K +71.5%	544K	$270M
Pictet Asset Management Holding SA	+202K +59.7%	539K	$268M
Dimensional Fund Advisors LP	+180K +18.2%	1.2M	$581M
Citadel Advisors LLC Hedge fund	+171K +50.4%	510K	$254M
Canada Pension Plan Investment Board	+165K +86.8%	355K	$176M
Bank Of America Corp	+161K +5.6%	3.0M	$1.5B
ING Groep NV	+158K +241.0%	223K	$111M
Invesco Ltd.	+150K +1.9%	8.0M	$4B
Harvest Portfolios Group Inc.	+148K New position	148K	$73.6M
Adage Capital Partners Gp, L.L.C. Hedge fund	+142K +56.3%	394K	$196M
State Street Corp Index funds	+141K +1.2%	11.9M	$5.9B

Biggest buyers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Franklin Resources Inc Active manager	+2.8M +507.3%	3.3M	$1.7B
Capital World Investors Active manager	+747K +2.9%	26.1M	$13B
AQR Capital Management LLC Hedge fund	+445K +260.3%	616K	$305M
Millennium Management LLC Hedge fund	+438K +1419.7%	468K	$233M
Hudson Bay Capital Management LP Hedge fund	+345K +767.6%	390K	$194M
Victory Capital Management Inc Active manager	+285K +15.1%	2.2M	$1.1B
Jennison Associates LLC Active manager	+258K +9.4%	3.0M	$1.5B
Marshall Wace, LLP Hedge fund	+227K +71.5%	544K	$270M
Citadel Advisors LLC Hedge fund	+171K +50.4%	510K	$254M
Adage Capital Partners Gp, L.L.C. Hedge fund	+142K +56.3%	394K	$196M

Biggest sellers

by change in shares held

Biggest sellers
Institution	Change in shares	Shares June 30, 2026	Value
Capital Research Global Investors Active manager	−1.6M −7.7%	19.5M	$9.7B
Alliancebernstein L.P. Active manager	−891K −22.8%	3.0M	$1.3B
FMR LLC Active manager	−563K −27.9%	1.5M	$724M
Jpmorgan Chase & Co	−516K −7.3%	6.5M	$3.3B
Capital International Investors Active manager	−431K −8.4%	4.7M	$2.3B
Edgewood Management LLC Active manager	−374K −41.3%	531K	$264M
Clearbridge Investments, LLC Active manager	−358K −13.3%	2.3M	$1.2B
Harding Loevner LP Active manager	−312K −99.6%	1,163	$577,661
B. Metzler Seel. Sohn & Co. AG	−280K −54.7%	231K	$115M
Vanguard Portfolio Management LLC Index funds	−267K −5.2%	4.9M	$2.4B
D. E. Shaw & Co., Inc. Hedge fund	−246K −98.8%	3,105	$1.5M
American Century Companies Inc Active manager	−232K −28.6%	581K	$289M
Manning & Napier Advisors LLC	−219K −99.1%	2,064	$1M
BNP Paribas Financial Markets	−153K −36.9%	262K	$130M
Royal Bank Of Canada	−132K −11.8%	980K	$487M
Geode Capital Management, LLC Index funds	−122K −2.0%	6.0M	$3B
Lazard Asset Management LLC Active manager	−120K −56.2%	93K	$46.3M
Connor, Clark & Lunn Investment Management Ltd.	−116K −46.3%	135K	$67.2M
Jane Street Group, LLC	−112K −90.9%	11K	$5.6M
Natixis Advisors, LLC	−105K −19.0%	449K	$223M

Biggest sellers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Capital Research Global Investors Active manager	−1.6M −7.7%	19.5M	$9.7B
Alliancebernstein L.P. Active manager	−891K −22.8%	3.0M	$1.3B
FMR LLC Active manager	−563K −27.9%	1.5M	$724M
Capital International Investors Active manager	−431K −8.4%	4.7M	$2.3B
Edgewood Management LLC Active manager	−374K −41.3%	531K	$264M
Clearbridge Investments, LLC Active manager	−358K −13.3%	2.3M	$1.2B
Harding Loevner LP Active manager	−312K −99.6%	1,163	$577,661
D. E. Shaw & Co., Inc. Hedge fund	−246K −98.8%	3,105	$1.5M
American Century Companies Inc Active manager	−232K −28.6%	581K	$289M
Lazard Asset Management LLC Active manager	−120K −56.2%	93K	$46.3M

New positions

largest by value

Institution	Shares	Value June 30, 2026
Harvest Portfolios Group Inc.	148K	$73.6M
Mn Services Vermogensbeheer B.V.	74K	$36.8M
Adams Diversified Equity Fund, Inc.	47K	$23.5M
Quadrature Capital LtdHedge fund	47K	$23.3M
Tudor Investment Corp Et AlHedge fund	30K	$15M
Cornerstone Advisors, LLC	25K	$12.3M
Ardsley Advisory Partners LP	15K	$7.5M
J. Goldman & Co LPHedge fund	12K	$6.1M
Canal Capital Management, LLC	9,045	$4.5M
Aware Super Pty Ltd As Trustee Of Aware Super	9,038	$4.5M

Sold out

largest by value

Institution	Shares	Value March 31, 2026
Smith Group Asset Management, LLC	56K	$24.9M
Gradient Investments LLC	42K	$18.6M
Caxton Associates LLPHedge fund	36K	$16.1M
Exoduspoint Capital Management, LPHedge fund	22K	$10M
Xtx Topco Ltd	16K	$7M
Trexquant Investment LPHedge fund	15K	$6.8M
ADAR1 Capital Management, LLCHedge fund	15K	$6.7M
Superstring Capital Management LP	11K	$4.9M
Group One Trading LLC	9,357	$4.2M
Emerald Investment Advisers, LLC	8,012	$3.6M

Who holds the shares

13F holdings at June 30, 2026

Institutions reporting: 1,739
Ten largest holders: 53.0%
Index fund managers: 29.0%
Active managers and hedge funds: 34.8%

Buying and selling by type of institution, March 31, 2026 to June 30, 2026
Type	Bought	Sold	New	Sold out	Net change in shares	Net %
Active managers and hedge funds	47	49	9	9	+674K	+0.8%
Index fund managers	6	6	0	0	−137K	−0.2%
Other institutions	817	662	159	99	+1.7M	+2.0%

Active managers and hedge funds: a list we maintain of about 400 well-known stock-picking firms and hedge funds, matched by SEC registration number (CIK) and checked against the filer names each quarter. Index fund managers: the large index houses, such as BlackRock, Vanguard, State Street, Geode and Northern Trust. Every other filer (banks, brokers, wealth managers, pension funds, insurers and firms not on the list) counts as another institution. A firm that files under several SEC registrations appears once for each.

What these filings can and cannot tell you

Form 13F lists the long positions in US-listed shares held by investment managers with more than $100 million in such holdings. Managers file it up to 45 days after each quarter ends, so this page shows what funds held at the end of each quarter, not what they are doing now: a position may have changed since. Short positions, most derivatives and smaller managers are not included, and a cut can mean a fund lost clients or rebalanced rather than a view on Vertex Pharmaceuticals.

Only managers that filed a holdings report for both quarters are compared (1,821 here). 54 other holders are left out: first-time or late filers, firms that changed their SEC registration, and filings that withheld positions under confidential treatment, any of which would otherwise look like a new position or a sale. Figures are as reported by each manager in the SEC's quarterly 13F data sets; option positions are excluded.

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