Xeris Biopharma Holdings, Inc.: which funds bought and sold

Institutions that bought and sold Xeris Biopharma Holdings shares in Q2 2026, from the holdings they reported to the SEC on Form 13F for March 31, 2026 and June 30, 2026.

Between March 31, 2026 and June 30, 2026, 136 institutions that filed 13F reports for both quarters added to or opened positions in Xeris Biopharma Holdings, and 91 cut or closed them. Together they added a net 2.2M shares, +2.1% on what they held at the start of the quarter. Active managers and hedge funds on our list were net sellers of 4.0M shares (−11.6%); index fund managers were net buyers of 2.9M shares (+8.1%). 32 opened a new position and 26 sold out entirely.

Bought, Q2 2026 136 institutions, 32 of them new holders Sold, Q2 2026 91 institutions, 26 of them sold out

Net change, all compared +2.2M shares (+2.1%)

Net change, active managers −4.0M shares (−11.6%), 26 bought, 21 sold

Buyers versus sellers

institutions compared, 260

136 bought 33 91 sold

Active managers and hedge funds 26 bought · 21 sold · −4.0M

Index fund managers 9 bought · 3 sold · +2.9M

Other institutions 101 bought · 67 sold · +3.3M

Biggest buyers

by change in shares held

Biggest buyers
Institution	Change in shares	Shares June 30, 2026	Value
Blackrock, Inc. Index funds	+1.6M +12.2%	14.5M	$115M
Nuveen, LLC	+1.5M +50.4%	4.4M	$34.7M
Dimensional Fund Advisors LP	+1.1M New position	1.1M	$8.5M
Arrowstreet Capital, Limited Partnership Hedge fund	+839K +627.3%	973K	$7.7M
Walleye Capital LLC Hedge fund	+611K New position	611K	$4.8M
Algert Global LLC Hedge fund	+586K +50.6%	1.7M	$13.8M
Federated Hermes, Inc. Active manager	+578K +67.4%	1.4M	$11.4M
Bank Of America Corp	+523K +59.8%	1.4M	$11.1M
First Trust Advisors LP	+485K New position	485K	$3.8M
Perceptive Advisors LLC Hedge fund	+467K New position	467K	$3.7M
Jpmorgan Chase & Co	+446K +72.8%	1.1M	$8.2M
Geode Capital Management, LLC Index funds	+428K +10.0%	4.7M	$37.4M
Vanguard Capital Management LLC Index funds	+359K +5.1%	7.3M	$58.1M
Cliffwater LLC	+263K New position	263K	$2.1M
Y-Intercept (Hong Kong) Ltd	+250K +154.2%	411K	$3.3M
Jefferies Financial Group Inc.	+206K +234.5%	294K	$2.3M
Royce & Associates LP Active manager	+205K +80.1%	461K	$3.7M
Ishara Investments LP	+205K +20.0%	1.2M	$9.7M
Aquatic Capital Management LLC	+200K New position	200K	$1.6M
HRT Financial LP	+195K +113.7%	366K	$2.9M

Biggest buyers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Arrowstreet Capital, Limited Partnership Hedge fund	+839K +627.3%	973K	$7.7M
Walleye Capital LLC Hedge fund	+611K New position	611K	$4.8M
Algert Global LLC Hedge fund	+586K +50.6%	1.7M	$13.8M
Federated Hermes, Inc. Active manager	+578K +67.4%	1.4M	$11.4M
Perceptive Advisors LLC Hedge fund	+467K New position	467K	$3.7M
Royce & Associates LP Active manager	+205K +80.1%	461K	$3.7M
Wellington Management Group LLP Active manager	+194K +8.9%	2.4M	$18.7M
Man Group PLC Hedge fund	+179K +64.7%	455K	$3.6M
Voleon Capital Management LP Hedge fund	+158K +340.2%	205K	$1.6M
AQR Capital Management LLC Hedge fund	+147K +10.5%	1.5M	$12.2M

Biggest sellers

by change in shares held

Biggest sellers
Institution	Change in shares	Shares June 30, 2026	Value
Millennium Management LLC Hedge fund	−2.1M −94.2%	132K	$1M
Voss Capital, LP Hedge fund	−1.4M Sold out	0	—
Qube Research & Technologies Ltd Hedge fund	−1.2M −29.7%	2.9M	$22.9M
Centerbook Partners LP Hedge fund	−968K −77.5%	281K	$2.2M
Driehaus Capital Management LLC Active manager	−903K Sold out	0	—
Jane Street Group, LLC	−664K −91.5%	62K	$490,367
Trexquant Investment LP Hedge fund	−494K −59.3%	339K	$2.7M
Renaissance Technologies LLC Hedge fund	−386K −85.1%	67K	$533,308
Voloridge Investment Management, LLC Hedge fund	−370K Sold out	0	—
UBS Group AG	−345K −21.0%	1.3M	$10.3M
Rosalind Advisors, Inc.	−323K −10.0%	2.9M	$23M
Connor, Clark & Lunn Investment Management Ltd.	−281K −68.8%	127K	$1M
Squarepoint Ops LLC Hedge fund	−249K −40.5%	366K	$2.9M
Sei Investments Co	−240K −41.4%	340K	$2.7M
Morgan Stanley	−236K −9.2%	2.3M	$18.5M
Emerald Mutual Fund Advisers Trust	−208K Sold out	0	—
F/M Investments LLC	−208K Sold out	0	—
Healthcare Of Ontario Pension Plan Trust Fund	−201K −43.2%	264K	$2.1M
Engineers Gate Manager LP Hedge fund	−186K Sold out	0	—
Canada Pension Plan Investment Board	−156K −41.5%	219K	$1.7M

Biggest sellers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Millennium Management LLC Hedge fund	−2.1M −94.2%	132K	$1M
Voss Capital, LP Hedge fund	−1.4M Sold out	0	—
Qube Research & Technologies Ltd Hedge fund	−1.2M −29.7%	2.9M	$22.9M
Centerbook Partners LP Hedge fund	−968K −77.5%	281K	$2.2M
Driehaus Capital Management LLC Active manager	−903K Sold out	0	—
Trexquant Investment LP Hedge fund	−494K −59.3%	339K	$2.7M
Renaissance Technologies LLC Hedge fund	−386K −85.1%	67K	$533,308
Voloridge Investment Management, LLC Hedge fund	−370K Sold out	0	—
Squarepoint Ops LLC Hedge fund	−249K −40.5%	366K	$2.9M
Engineers Gate Manager LP Hedge fund	−186K Sold out	0	—

New positions

largest by value

Institution	Shares	Value June 30, 2026
Dimensional Fund Advisors LP	1.1M	$8.5M
Walleye Capital LLCHedge fund	611K	$4.8M
First Trust Advisors LP	485K	$3.8M
Perceptive Advisors LLCHedge fund	467K	$3.7M
Cliffwater LLC	263K	$2.1M
Aquatic Capital Management LLC	200K	$1.6M
Corient Private Wealth LP	184K	$1.5M
American Century Companies IncActive manager	93K	$739,292
Varcov Co.	71K	$560,356
Susquehanna Portfolio Strategies, LLC	60K	$479,049

Sold out

largest by value

Institution	Shares	Value March 31, 2026
Voss Capital, LPHedge fund	1.4M	$8M
Driehaus Capital Management LLCActive manager	903K	$5.2M
Voloridge Investment Management, LLCHedge fund	370K	$2.1M
Emerald Mutual Fund Advisers Trust	208K	$1.2M
F/M Investments LLC	208K	$1.2M
Engineers Gate Manager LPHedge fund	186K	$1.1M
Twinbeech Capital LP	97K	$563,760
Integrated Quantitative Investments LLC	66K	$383,786
Stonepine Capital Management, LLC	40K	$232,174
Drw Securities, LLC	37K	$213,480

Who holds the shares

13F holdings at June 30, 2026

Institutions reporting: 238
Ten largest holders: 50.4%
Index fund managers: 35.8%
Active managers and hedge funds: 27.9%

Buying and selling by type of institution, March 31, 2026 to June 30, 2026
Type	Bought	Sold	New	Sold out	Net change in shares	Net %
Active managers and hedge funds	26	21	6	5	−4.0M	−11.6%
Index fund managers	9	3	1	0	+2.9M	+8.1%
Other institutions	101	67	25	21	+3.3M	+9.5%

Active managers and hedge funds: a list we maintain of about 400 well-known stock-picking firms and hedge funds, matched by SEC registration number (CIK) and checked against the filer names each quarter. Index fund managers: the large index houses, such as BlackRock, Vanguard, State Street, Geode and Northern Trust. Every other filer (banks, brokers, wealth managers, pension funds, insurers and firms not on the list) counts as another institution. A firm that files under several SEC registrations appears once for each.

What these filings can and cannot tell you

Form 13F lists the long positions in US-listed shares held by investment managers with more than $100 million in such holdings. Managers file it up to 45 days after each quarter ends, so this page shows what funds held at the end of each quarter, not what they are doing now: a position may have changed since. Short positions, most derivatives and smaller managers are not included, and a cut can mean a fund lost clients or rebalanced rather than a view on Xeris Biopharma Holdings.

Only managers that filed a holdings report for both quarters are compared (260 here). 9 other holders are left out: first-time or late filers, firms that changed their SEC registration, and filings that withheld positions under confidential treatment, any of which would otherwise look like a new position or a sale. Figures are as reported by each manager in the SEC's quarterly 13F data sets; option positions are excluded.

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