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Ascentage Pharma Group International vs Protalix Biotherapeutics

Ascentage Pharma Group International is the larger business, with $79.9m of revenue in fiscal 2025 against $52.7m for Protalix Biotherapeutics (1.5 times as much). Protalix Biotherapeutics grew faster (-1.2% against -41.4%). Protalix Biotherapeutics kept more of each dollar of sales as profit: a net margin of -12.5% against -216.5%. Protalix Biotherapeutics carries less debt relative to equity (0.0% against 150.1%).

Latest fiscal yearAscentage Pharma Group InternationalAAPG, 2025Protalix BiotherapeuticsPLX, 2025
Revenue $79.9m $52.7m
Revenue growth -41.4% -1.2%
Net income −$173m −$6.6m
Operating margin — -10.4%
Net margin -216.5% -12.5%
Return on equity -153.3% -14.4%
Free cash flow −$167m −$13.6m
Cash $171m $14.7m
Total debt $284m $0
Debt to equity 150.1% 0.0%
Dividend per share — —
Dividend yield — —
Share buybacks $1.3m —
Employees — 226
Market value $1.26bn $203m
Price vs our value range — —
Moat score — 27 (Weak)
Insider trades, 12 months 0 buys, 0 sales 1 buys, 1 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

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Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.