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Ascentage Pharma Group International vs Bicycle Therapeutics

Ascentage Pharma Group International and Bicycle Therapeutics are similar in size: $79.9m and $72.6m of revenue in their latest fiscal years. Bicycle Therapeutics grew faster (105.8% against -41.4%). Ascentage Pharma Group International kept more of each dollar of sales as profit: a net margin of -216.5% against -301.7%. Bicycle Therapeutics carries less debt relative to equity (0.0% against 150.1%).

Latest fiscal yearAscentage Pharma Group InternationalAAPG, 2025Bicycle TherapeuticsBCYC, 2025
Revenue $79.9m $72.6m
Revenue growth -41.4% 105.8%
Net income −$173m −$219m
Operating margin — -340.4%
Net margin -216.5% -301.7%
Return on equity -153.3% -31.2%
Free cash flow −$167m −$252m
Cash $171m $628m
Total debt $284m $0
Debt to equity 150.1% 0.0%
Dividend per share — —
Dividend yield — —
Share buybacks $1.3m —
Employees — 288
Market value $1.26bn $255m
Price vs our value range — —
Moat score — 8 (Weak)
Insider trades, 12 months 0 buys, 0 sales 0 buys, 0 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

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Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.