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Adaptive Biotechnologies vs Iovance Biotherapeutics

Adaptive Biotechnologies and Iovance Biotherapeutics are similar in size: $277m and $264m of revenue in their latest fiscal years. Iovance Biotherapeutics grew faster (60.6% against 54.8%). Adaptive Biotechnologies kept more of each dollar of sales as profit: a net margin of -21.5% against -148.4%.

Latest fiscal yearAdaptive BiotechnologiesADPT, 2025Iovance BiotherapeuticsIOVA, 2025
Revenue $277m $264m
Revenue growth 54.8% 60.6%
Net income −$59.5m −$391m
Operating margin -20.6% —
Net margin -21.5% -148.4%
Return on equity -28.2% -55.5%
Free cash flow −$48.9m −$336m
Cash $70.5m $163m
Total debt $131m —
Debt to equity 60.0% —
Dividend per share — —
Dividend yield — —
Share buybacks — —
Employees 624 975
Market value $4.10bn $3.95bn
Price vs our value range — —
Moat score 24 (Weak) —
Insider trades, 12 months 0 buys, 168 sales 0 buys, 0 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

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Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.