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Astrazeneca vs Pfizer

Astrazeneca and Pfizer are similar in size: $58.74bn and $62.58bn of revenue in their latest fiscal years. Astrazeneca grew faster (8.6% against -1.6%). Astrazeneca kept more of each dollar of sales as profit: a net margin of 17.4% against 12.4%.

Latest fiscal yearAstrazenecaAZN, 2025PfizerPFE, 2025
Revenue $58.74bn $62.58bn
Revenue growth 8.6% -1.6%
Net income $10.22bn $7.77bn
Operating margin 23.4% —
Net margin 17.4% 12.4%
Return on equity 22.9% 8.9%
Free cash flow $11.77bn $9.07bn
Cash $5.71bn $1.14bn
Total debt $29.62bn $64.80bn
Debt to equity 60.9% —
Dividend per share — $1.72
Dividend yield 1.7% 5.5%
Share buybacks $521m —
Employees — 75,000
Market value $286.25bn $172.19bn
Price vs our value range Within our value range Within our value range
Moat score — 78 (Strong)
Insider trades, 12 months 1 buys, 1 sales 3 buys, 2 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

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Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.