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Crispr Therapeutics vs Prelude Therapeutics

Prelude Therapeutics is the larger business, with $12.1m of revenue in fiscal 2025 against $3.5m for Crispr Therapeutics (3.5 times as much). Prelude Therapeutics grew faster (73.4% against -90.6%). Prelude Therapeutics kept more of each dollar of sales as profit: a net margin of -819.6% against -16569.8%. Crispr Therapeutics carries less debt relative to equity (0.0% against 0.0%).

Latest fiscal yearCrispr TherapeuticsCRSP, 2025Prelude TherapeuticsPRLD, 2025
Revenue $3.5m $12.1m
Revenue growth -90.6% 73.4%
Net income −$582m −$99.5m
Operating margin -18933.6% -861.3%
Net margin -16569.8% -819.6%
Return on equity -30.2% -99.5%
Free cash flow −$346m −$56.4m
Cash $348m $35.3m
Total debt $0 $0
Debt to equity 0.0% 0.0%
Dividend per share — —
Dividend yield — —
Share buybacks — —
Employees — 79
Market value $4.83bn $372m
Price vs our value range — —
Moat score 10 (Weak) —
Insider trades, 12 months 0 buys, 30 sales 4 buys, 0 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

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Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.