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Cytomx Therapeutics vs Pyxis Oncology

Cytomx Therapeutics is the larger business, with $76.2m of revenue in fiscal 2025 against $13.9m for Pyxis Oncology (5.5 times as much). Pyxis Oncology grew faster (-14.2% against -44.8%). Cytomx Therapeutics kept more of each dollar of sales as profit: a net margin of -22.8% against -574.5%. Cytomx Therapeutics carries less debt relative to equity (0.0% against 0.0%).

Latest fiscal yearCytomx TherapeuticsCTMX, 2025Pyxis OncologyPYXS, 2025
Revenue $76.2m $13.9m
Revenue growth -44.8% -14.2%
Net income −$17.4m −$79.6m
Operating margin -29.3% -609.2%
Net margin -22.8% -574.5%
Return on equity -35.2% -91.4%
Free cash flow −$75.8m −$63.5m
Cash $12.7m $15.4m
Total debt $0 $0
Debt to equity 0.0% 0.0%
Dividend per share — —
Dividend yield — —
Share buybacks — —
Employees 69 56
Market value $372m $104m
Price vs our value range — —
Moat score 9 (Weak) —
Insider trades, 12 months 0 buys, 7 sales 1 buys, 1 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

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Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.