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Nurix Therapeutics vs Ultragenyx Pharmaceutical

Ultragenyx Pharmaceutical is the larger business, with $673m of revenue in fiscal 2025 against $84.0m for Nurix Therapeutics (8.0 times as much). Nurix Therapeutics grew faster (54.0% against 20.2%). Ultragenyx Pharmaceutical kept more of each dollar of sales as profit: a net margin of -85.4% against -314.9%.

Latest fiscal yearNurix TherapeuticsNRIX, 2025Ultragenyx PharmaceuticalRARE, 2025
Revenue $84.0m $673m
Revenue growth 54.0% 20.2%
Net income −$264m −$575m
Operating margin -340.2% -79.5%
Net margin -314.9% -85.4%
Return on equity -49.6% —
Free cash flow −$263m −$472m
Cash $247m $421m
Total debt $0 $0
Debt to equity 0.0% —
Dividend per share — —
Dividend yield — —
Share buybacks — —
Employees 317 1,371
Market value $2.81bn $1.65bn
Price vs our value range — —
Moat score 11 (Weak) 8 (Weak)
Insider trades, 12 months 0 buys, 44 sales 0 buys, 28 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

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Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.