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Stoke Therapeutics vs Tonix Pharmaceuticals Holding

Stoke Therapeutics is the larger business, with $184m of revenue in fiscal 2025 against $13.1m for Tonix Pharmaceuticals Holding (14.1 times as much). Stoke Therapeutics grew faster (404.5% against 29.8%). Stoke Therapeutics kept more of each dollar of sales as profit: a net margin of -3.7% against -946.2%.

Latest fiscal yearStoke TherapeuticsSTOK, 2025Tonix Pharmaceuticals HoldingTNXP, 2025
Revenue $184m $13.1m
Revenue growth 404.5% 29.8%
Net income −$6.9m −$124m
Operating margin -11.2% —
Net margin -3.7% -946.2%
Return on equity -2.4% -64.5%
Free cash flow $44.9m −$103m
Cash $84.2m $208m
Total debt $0 —
Debt to equity 0.0% —
Dividend per share — —
Dividend yield — —
Share buybacks — $13.8m
Employees 170 142
Market value $1.69bn $86.9m
Price vs our value range — —
Moat score — —
Insider trades, 12 months 0 buys, 83 sales 7 buys, 0 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

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Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.