undamentalytics Newsletter

Cabaletta Bio, Inc.: which funds bought and sold

Institutions that bought and sold Cabaletta Bio shares in Q2 2026, from the holdings they reported to the SEC on Form 13F for March 31, 2026 and June 30, 2026.

Between March 31, 2026 and June 30, 2026, 103 institutions that filed 13F reports for both quarters added to or opened positions in Cabaletta Bio, and 43 cut or closed them. Together they added a net 69.9M shares, +82.5% on what they held at the start of the quarter. Active managers and hedge funds on our list were net buyers of 24.1M shares (+44.3%); index fund managers were net buyers of 24.6M shares (+276.8%). 54 opened a new position and 23 sold out entirely.

Bought, Q2 2026 103 institutions, 54 of them new holders Sold, Q2 2026 43 institutions, 23 of them sold out
Net change, all compared +69.9M shares (+82.5%)
Net change, active managers +24.1M shares (+44.3%), 18 bought, 21 sold

Buyers versus sellers

institutions compared, 161
Active managers and hedge funds 18 bought · 21 sold · +24.1M
Index fund managers 11 bought · 1 sold · +24.6M
Other institutions 74 bought · 21 sold · +21.1M

Biggest buyers

by change in shares held
Biggest buyers
Institution Change in shares Shares June 30, 2026 Value
Jennison Associates LLC Active manager +11.1M +123.3% 20.0M $62.3M
Blackrock, Inc. Index funds +8.4M +353.2% 10.8M $33.4M
T. Rowe Price Investment Management, Inc. Active manager +7.8M +70.3% 18.9M $58.7M
Bain Capital Life Sciences Investors, LLC +7.6M +78.2% 17.2M $53.6M
State Street Corp Index funds +7.4M +1568.0% 7.8M $24.4M
Price T Rowe Associates Inc Active manager +4.0M +899.1% 4.4M $13.7M
Citadel Advisors LLC Hedge fund +3.5M New position 3.5M $11M
Vanguard Capital Management LLC Index funds +3.2M +79.4% 7.2M $22.5M
Woodline Partners LP Hedge fund +2.9M +235.9% 4.2M $13.1M
Opaleye Management Inc. +2.5M +180.0% 3.9M $12M
Franklin Resources Inc Active manager +2.4M New position 2.4M $7.5M
Geode Capital Management, LLC Index funds +2.3M +205.3% 3.5M $10.8M
Goldman Sachs Group Inc +1.4M +182.4% 2.2M $6.9M
Vanguard Portfolio Management LLC Index funds +1.4M New position 1.4M $4.4M
Sphera Funds Management Ltd. +1.3M New position 1.3M $4.1M
Stonepine Capital Management, LLC +867K +1734.2% 917K $2.9M
UBS Group AG +865K +142.6% 1.5M $4.6M
Cantor Fitzgerald, L. P. +835K +109.2% 1.6M $5M
Ameriprise Financial Inc +828K New position 828K $2.6M
Northern Trust Corp Index funds +769K +322.4% 1.0M $3.1M

Biggest sellers

by change in shares held
Biggest sellers
Institution Change in shares Shares June 30, 2026 Value
Millennium Management LLC Hedge fund −3.8M −65.0% 2.1M $6.4M
Two Sigma Investments, LP Hedge fund −1.1M −43.5% 1.4M $4.4M
Marshall Wace, LLP Hedge fund −614K −28.2% 1.6M $4.9M
Qube Research & Technologies Ltd Hedge fund −508K −26.3% 1.4M $4.4M
Renaissance Technologies LLC Hedge fund −501K −24.6% 1.5M $4.8M
Cormorant Asset Management, LP Hedge fund −500K −9.1% 5.0M $15.6M
Jane Street Group, LLC −249K Sold out 0 —
Point72 Asset Management, L.P. Hedge fund −247K Sold out 0 —
683 Capital Management, LLC Hedge fund −225K Sold out 0 —
Almitas Capital LLC −211K −62.7% 126K $391,549
Ikarian Capital, LLC −200K −22.2% 700K $2.2M
Hudson Bay Capital Management LP Hedge fund −162K Sold out 0 —
Brevan Howard Capital Management LP Hedge fund −150K Sold out 0 —
Squarepoint Ops LLC Hedge fund −145K Sold out 0 —
Diametric Capital, LP −127K −48.4% 136K $421,709
Exoduspoint Capital Management, LP Hedge fund −106K Sold out 0 —
D. E. Shaw & Co., Inc. Hedge fund −99K −52.1% 91K $281,928
American Century Companies Inc Active manager −98K −90.7% 10K $31,420
Nomura Holdings Inc −96K Sold out 0 —
Quadrature Capital Ltd Hedge fund −87K Sold out 0 —

New positions

largest by value
InstitutionSharesValue June 30, 2026
Citadel Advisors LLCHedge fund 3.5M $11M
Franklin Resources IncActive manager 2.4M $7.5M
Vanguard Portfolio Management LLCIndex funds 1.4M $4.4M
Sphera Funds Management Ltd. 1.3M $4.1M
Ameriprise Financial Inc 828K $2.6M
Heights Capital Management, Inc 756K $2.3M
Blue Owl Capital Holdings LP 715K $2.2M
Nuveen, LLC 646K $2M
Manufacturers Life Insurance Company, The 182K $566,191
Panagora Asset Management IncActive manager 162K $503,559

Sold out

largest by value
InstitutionSharesValue March 31, 2026
Jane Street Group, LLC 249K $668,718
Point72 Asset Management, L.P.Hedge fund 247K $663,394
683 Capital Management, LLCHedge fund 225K $605,250
Hudson Bay Capital Management LPHedge fund 162K $435,043
Brevan Howard Capital Management LPHedge fund 150K $402,749
Squarepoint Ops LLCHedge fund 145K $389,192
Exoduspoint Capital Management, LPHedge fund 106K $285,100
Nomura Holdings Inc 96K $256,927
Quadrature Capital LtdHedge fund 87K $234,191
Omers Administration Corp 54K $145,529

Who holds the shares

13F holdings at June 30, 2026
Institutions reporting
140
Ten largest holders
66.0%
of 13F-reported shares
Index fund managers
21.1%
of 13F-reported shares
Active managers and hedge funds
49.6%
of 13F-reported shares
Buying and selling by type of institution, March 31, 2026 to June 30, 2026
TypeBoughtSoldNewSold outNet change in sharesNet %
Active managers and hedge funds 18 21 9 10 +24.1M +44.3%
Index fund managers 11 1 4 0 +24.6M +276.8%
Other institutions 74 21 41 13 +21.1M +99.5%

Active managers and hedge funds: a list we maintain of about 400 well-known stock-picking firms and hedge funds, matched by SEC registration number (CIK) and checked against the filer names each quarter. Index fund managers: the large index houses, such as BlackRock, Vanguard, State Street, Geode and Northern Trust. Every other filer (banks, brokers, wealth managers, pension funds, insurers and firms not on the list) counts as another institution. A firm that files under several SEC registrations appears once for each.

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