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Nautilus Biotechnology, Inc. (NAUT) stock

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NASDAQ: NAUT Nasdaq Life Sciences Tools & Services Next results ~January 26, 2027

Nautilus Biotechnology, Inc. is a US-listed company in the life sciences tools & services industry. Its financial year ends in December.

Stock price today

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Third-party market data · may be delayed

Model estimate per share

~$0.8

Growth cash-flow model

Base case. Range ~$0.8–$0.9. Revenue for this year and next from analysts' consensus, then growth fading to 2.5%; the operating margin moving to profitable peers'; investment needed per dollar of growth from peers; reduced by a failure probability.

Price vs value

No Buy/Hold/Sell rating is issued: limited reported history: available models are shown without a Buy/Hold/Sell rating.

Who’s trading

What company insiders, investment funds and members of Congress have been doing with the stock, from their own filings.

  • Insiders2 buying, 1 selling2 purchases and 2 sales by directors and officers, last 12 monthsInsider trades
  • Funds59 adding, 28 cuttingOf 22 active managers that changed their stake, 13 added; quarter to June 30, 2026Fund buyers and sellers

The Fundamentalytics view

Next results ~January 26, 2027 (estimated)

Current signal Results well ahead of expectations: Reported earnings per share beat the analysts' consensus estimate by 16% in the quarter to 2026-09-30, the 4th beat in the last four quarters.

Assembled from SEC-filed figures — the full workings are on this page and in our methodology. Observations, not recommendations.

Strengths

  • Beating expectations. Earnings per share beat the analysts' consensus estimate in each of the last four quarters.

Things to watch

  • Volatile shares. Over the past year the shares showed annualised volatility of 124% and a beta of 1.5 against the S&P 500.
  • Short interest rising. Shares sold short rose 38% in a month to 9.0% of tradable shares.

Latest results

Earnings per share
-$0.12 against an average estimate of -$0.14: beat by 15.8%
Share reaction
+31.6% in the first session after the results on October 27, 2026, against +0.9% for the S&P 500
Next report
October 27, 2026

Nautilus Biotechnology's figures from its SEC filings and results release; estimates are the analysts' average. Not a recommendation.

Price chart

  • 1 day+0.9%
  • 1 week-18.5%
  • 1 month+20.2%
  • This year+19.7%
  • 1 year+27.3%
  • 5 years-58.8%
  • S&P 500 this year+11.2%

Closing prices to 2026-11-02. Price change only, dividends excluded.

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Third-party market data · may be delayed

At a glance

Trailing twelve months, from SEC filings

Profitability

EPS (TTM, diluted)
$-0.46

Growth

Share count change
+0.6%

Earnings

Last results
October 27, 2026
Next results (est.)
January 26, 2027

News & updates

Updated October 31, 2026

Company announcements, filed results and changes that matter to shareholders.

  1. Results
  2. Agreement
  3. Results

Refreshed hourly when new source data is available. Summaries are checked against company releases and SEC filings. Company announcement headlines are labelled when a checked summary is unavailable.

Fundamentalytics rating

model v1.6 · 2026-11-03

Not rated: limited reported history: available models are shown without a Buy/Hold/Sell rating.

Valuation models

We value Nautilus Biotechnology, Inc. as an operating company, with every model that fits that kind of business. Cost of equity 9.3%: the 10-year Treasury yield (4.9%) plus a beta of 0.97 times a 4.5% equity risk premium.

Value per share by model
Model Value per share In the combined value?
Growth cash-flow model Revenue for this year and next from analysts' consensus, then growth fading to 2.5%; the operating margin moving to profitable peers'; investment needed per dollar of growth from peers; reduced by a failure probability. For young or fast-growing companies. The starting margin is normalized to between -100% and 60%; net margin is a proxy when operating income is not tagged. Uses analysts' consensus estimates (third-party data), not our forecasts. ~$0.8 ~$0.8–$0.9 Primary model, counts double
Price-to-earnings vs peers Earnings per share times peers' typical (harmonic-mean) price-to-earnings. — Does not apply: no positive earnings in the latest twelve months
Residual income Book value plus the present value of returns above the cost of equity, fading over ten years. — Does not apply: the model gives no positive value
Justified price-to-book Book value times (return on equity - growth) / (cost of equity - growth): steady-state returns. — Does not apply: return on equity is not positive
Forward price-to-sales vs peers Next year's consensus sales per share times peers' typical forward price-to-sales; only when earnings are negative. Uses analysts' consensus estimates (third-party data), not our forecasts. ~$0.1 ~$0.1–$0.3 Left out: out of range vs price (0.06x)
Revenue-to-maturity model Revenue grown to maturity with the cash margin moving to the industry's; for companies not yet profitable. — Does not apply: revenue and margins don't support a positive value
Combined value Weighted average of the models that apply: the primary model (growth cash-flow model) counts double. Models more than 5x or less than 0.2x the share price, or more than 3x away from the other models' median, are left out. ~$0.8 ~$0.8–$0.9 1 model

Different models fail in different ways, so where several apply we average them rather than trust one. Peer-based models compare Nautilus Biotechnology, Inc. with Life Sciences Tools & Services in our coverage, using third-party market data. Model values are estimates under stated assumptions, updated as new filings arrive; not price targets or investment advice. How each model works.

Moat

Not assessed: fewer than five years of comparable figures in the filings. AI disruption exposure for this industry: Medium.

A rules-based reading of reported figures, not a forecast and not investment advice. How the score is built: methodology.

Forecasts and guidance

Analysts' consensus

Nautilus Biotechnology, Inc.: consensus estimates
Fiscal yearEPSGrowthRevenueGrowth
Current −$0.48 −3% $691330 0%
Next −$0.48 0% $6m +709%

How the EPS forecast has moved

The consensus EPS forecast for the current fiscal year is −4.0% on 90 days ago. In the last 30 days, 1 analyst raised Nautilus Biotechnology, Inc.'s forecast and 0 cut it.

Consensus EPS forecast Nautilus Biotechnology, Inc., last 90 days
−$0.60 −$0.40 −$0.20 $0.00 90 days ago 60 days ago 30 days ago 7 days ago Now Current fiscal year, 90 days ago: −$0.51 Current fiscal year, 60 days ago: −$0.51 Current fiscal year, 30 days ago: −$0.51 Current fiscal year, 7 days ago: −$0.51 Current fiscal year, Now: −$0.48 −$0.48 Next fiscal year, 90 days ago: −$0.52 Next fiscal year, 60 days ago: −$0.52 Next fiscal year, 30 days ago: −$0.52 Next fiscal year, 7 days ago: −$0.52 Next fiscal year, Now: −$0.48 −$0.48

Average of analysts' published estimates (third-party data).

View chart data
Period Current fiscal yearNext fiscal year
90 days ago −$0.51−$0.52
60 days ago −$0.51−$0.52
30 days ago −$0.51−$0.52
7 days ago −$0.51−$0.52
Now −$0.48−$0.48

Earnings against estimates

Nautilus Biotechnology, Inc.: reported EPS against the consensus estimate
Quarter toEstimateActualSurprise
Sept 2026 −$0.14 −$0.12 +15.8%
Jun 2026 −$0.14 −$0.11 +21.4%
Mar 2026 −$0.14 −$0.12 +17.2%
Dec 2025 −$0.14 −$0.11 +21.4%

Adjusted EPS as companies report it, against the average analyst estimate.

Analyst recommendations

4 analysts, Oct 2026
Buy4100%
Hold00%
Sell00%

Monthly trend

  1. Oct 202644
  2. Sep 202644
  3. Aug 202622

Counts of recommendations published by analysts covering Nautilus Biotechnology, Inc., by month. Source: Aggregated broker recommendations (third-party data). Aggregated counts only: we do not reproduce any firm's recommendation or price target, and these are not Fundamentalytics ratings.

Positioning

Short interest
9.0%
of tradable shares
Days to cover
0.69
at average volume
Short interest, 1 month
+38%
to October 15, 2026
Held by institutions
43%
of shares
Held by insiders
32.0%
of shares
Employees
128
full time

Consensus figures average analysts' published estimates (third-party data); guidance is the company's own. Neither is our forecast. Short interest is reported twice a month and lags. Market data may be delayed.

This section is general information, not investment advice or a personal recommendation, and it does not take account of your objectives or circumstances. Forecasts and guidance are estimates, not promises: companies miss their own guidance and analysts' figures are often revised. Prices can fall as well as rise, and you can lose money. See our disclaimer.

Share-price performance

Market data may be delayed

Return and risk by year

Nautilus Biotechnology, Inc.: yearly return, monthly win rate and worst fall against the S&P 500
Calendar year 202120222023202420252026 to date
Return
NAUT−52%−65%+66%−44%+16%+20%
Industry peers (median)+5%−51%−3%−13%−7%+15%
S&P 500+29%−18%+26%+25%+18%+11%
Months that ended higher
NAUT33%42%58%33%50%46%
S&P 50075%42%67%75%75%46%
Largest fall from a high during the year
NAUT−80%−71%−48%−48%−69%−78%
S&P 500−5%−25%−10%−8%−19%−9%

Worst fall since August 7, 2020: 97% from February 8, 2021 to September 3, 2025. Getting back needed a 3410% gain, and the shares have not yet recovered.

Price behaviour

52-week range
$0.85 – $3.95
From 52-week high
−40.9%
vs 50-day average
+44.2%
vs 200-day average
+10.2%
Volatility (1 year)
124%
Beta vs S&P 500
1.48

Volatility is the annualised standard deviation of daily returns. Beta 1.5 means the shares typically moved 1.5% for each 1% move in the S&P 500 over the past year. Prices to November 2, 2026.

Share price after results

Next day
5 up, 7 down
typical move ±10.6%
After a week
3 up, 8 down
typical move ±13.5%
After a month
5 up, 6 down
typical move ±20.4%
Nautilus Biotechnology, Inc.: share-price change after each results release
Results releasedNext dayS&P 500 next day5 days21 days
October 27, 2026 +31.6% +0.9% — —
July 28, 2026 −37.3% −1.3% −40.7% −43.6%
April 28, 2026 −2.7% −0.5% +11.3% +1.2%
February 26, 2026 −16.3% −1.0% −15.6% +20.4%
October 28, 2025 +4.4% +0.3% +17.8% +68.1%
July 31, 2025 +0.5% −2.0% −2.0% −10.5%
April 29, 2025 +1.3% +0.7% −1.8% +17.6%
February 27, 2025 −9.1% −0.1% −20.3% −37.9%
October 29, 2024 −5.7% −0.1% −6.0% −18.1%
July 30, 2024 −1.1% +1.1% −16.4% −4.4%
April 30, 2024 +8.2% −1.9% +7.4% +2.7%
February 28, 2024 −8.5% +0.2% −8.8% 0.0%

From the close before the release date to the close 1, 5 and 21 trading days after it, so releases before the open and after the close are both captured. Past moves don't predict future ones.

Fundamentals

Data: SEC EDGAR XBRL company facts (as filed in 10-K/10-Q); forms 10-K, 10-Q. Generated November 3, 2026. Definitions in our methodology.

Dividends, buybacks and capital spending

Diluted share count
+0.6%
year over year
Reported value
$93.7M
Institutions reporting
92
Shares held vs prior quarter
▼ 7.7%
Positions opened / closed
31 / 16

Top buyers and sellers, Q2 2026: 59 institutions bought and 28 sold ; the biggest buyer was Blackrock, Inc (+2.5M shares) and the biggest seller A16Z Capital Management, L.L.C (−8.6M). See which funds bought and sold →

Largest reported holders, June 30, 2026
Manager Value Shares Share of 13F value Shares QoQ
Perceptive Advisors LLC $21.8M 11.6M 23.2% ▼ 7.6%
A16Z Capital Management, L.L.C. $16.9M 9.1M 18.1% ▼ 48.7%
Cercano Management LLC $13.4M 7.2M 14.3% 0.0%
Blackrock, Inc. $5M 2.7M 5.4% ▲ 1331.9%
Vanguard Capital Management LLC $4.8M 2.5M 5.1% ▲ 0.2%
Comprehensive Financial Management LLC $4.1M 2.2M 4.4% 0.0%
Citadel Advisors LLC $3.5M 1.9M 3.8% New
Geode Capital Management, LLC $2.4M 1.3M 2.5% ▲ 109.7%
Acadian Asset Management LLC $2M 1.1M 2.1% ▲ 42.4%
Clearstead Advisors, LLC $1.7M 893K 1.8% ▼ 61.7%
Susquehanna International Group, LLP $1.7M 891K 1.8% New
Sentinel Trust Co Lba $1.4M 750K 1.5% 0.0%

From Form 13F filings with the SEC ( quarterly data sets), as reported by each manager for June 30, 2026 and filed up to 45 days later. 13F reports cover long US-listed positions of managers above $100M only, so this is not Nautilus Biotechnology, Inc.'s complete shareholder register. Values are as reported by the filers .

Insider trading activity

Full insider history and chart
Recent insider open-market transactions
Insider Date Trade Shares Price Value
Ah Equity Partners Bio Ii, L.L.C. 10% owner June 2, 2026 Sell 384,026 $2.35 $902,461
Ah Equity Partners Bio Ii, L.L.C. 10% owner June 2, 2026 Sell 4,615,974 $2.35 $10.8M
Patel Sujal M CEO, President, and Secretary March 4, 2026 Buy 25,000 $2.61 $65,238
Suzuki Kentaro Chief Marketing Officer November 6, 2025 Buy 4,000 $1.49 $5,960

From insiders' Form 4 filings with the SEC. Excludes awards, option exercises and shares withheld for tax. "Pre-set plan" means the filing marks the trade as made under a Rule 10b5-1 plan. See every insider trade since five years ago, on a price chart.

Earnings dates and SEC filings

Results announcements

Next expected around January 26, 2027 estimated from the company's past filing pattern, not announced

  • October 27, 2026
  • July 28, 2026
  • April 28, 2026
  • February 26, 2026
  • October 28, 2025
  • July 31, 2025

Recent SEC filings

Data status

When each part of this page on Nautilus Biotechnology, Inc. was last updated.

DataLast updatedSource
Share priceExchange closing prices
News and updatesCompany releases and SEC 8-K filings
Analyst estimatesAggregated analyst estimates
Valuation and scoresOur models, from the filed figures

How we build and check these figures: methodology and data sources.

Nautilus Biotechnology, Inc. in brief

What does Nautilus Biotechnology, Inc. do?
Nautilus Biotechnology, Inc. is a US-listed company in the life sciences tools & services industry. Its financial year ends in December.
What is Nautilus Biotechnology, Inc.'s stock ticker?
Nautilus Biotechnology, Inc. trades under the ticker NAUT on Nasdaq. This page brings together its financial statements, valuation models, ownership and recent company updates.
Who are Nautilus Biotechnology, Inc.'s largest institutional shareholders?
By value reported in 13F filings for June 30, 2026, the largest reported holders are Perceptive Advisors LLC, A16Z Capital Management, L.L.C. and Cercano Management LLC. 13F reports cover long US-listed positions of managers above $100M, filed up to 45 days after quarter end.
Are insiders buying or selling Nautilus Biotechnology, Inc. stock?
Over the last 12 months, Nautilus Biotechnology, Inc.'s directors and officers reported 2 open-market purchases and 2 sales on Form 4. The insider trading page charts every trade.
When is Nautilus Biotechnology, Inc.'s next earnings date?
Around January 26, 2027, estimated from the spacing of its past results announcements (8-K filings). That is an estimate, not a confirmed date — Nautilus Biotechnology, Inc. announces its own schedule.