Orchestra Biomed Holdings, Inc. income statement

In fiscal 2025, Orchestra Biomed Holdings, Inc. reported revenue of $33.5m, up 1169.2% on the year before, operating income of −$51.8m (a -154.7% margin) and net income of −$52.7m, or −$1.11 per diluted share. Every line below comes from the company's 10-K and 10-Q filings; column headings link to the filing.

Income statement

US$ millions unless shown otherwise. Fiscal years, plus the last twelve months (LTM) when newer.

Orchestra Biomed Holdings, Inc.: income statement, annual
Fiscal year	2022Dec 2022	2023Dec 2023	2024Dec 2024	2025Dec 2025	LTMJun 2026
Revenue	4	3	3	33	32
Cost of revenue	0	0	0	0	0
Gross profit	3	3	2	33	32
Research and development	22	34	43	58	63
Selling, general and administrative	14	20	24	27	27
Operating income	−33	−52	−64	−52	−58
Interest expense	1	1	0	—	—
Net interest income	0	4	—	—	—
Income tax	—	—	—	0	—
Net income	−34	−49	−61	−53	−59
Diluted EPS	−$2.24	−$1.48	−$1.66	−$1.11	−$0.98
Diluted shares (average)	15m	33m	37m	48m	60m
EBITDA	−32	−51	−64	−51	−58

US$ millions unless shown otherwise. Fiscal quarters.

Orchestra Biomed Holdings, Inc.: income statement, quarterly
Quarter	2024 Q3Sept 2024	2024 Q4Dec 2024	2025 Q1Mar 2025	2025 Q2Jun 2025	2025 Q3Sept 2025	2025 Q4Dec 2025	2026 Q1Mar 2026	2026 Q2Jun 2026
Revenue	1	0	1	1	1	31	0	0
Cost of revenue	0	0	0	0	0	0	0	0
Gross profit	1	0	1	1	1	31	0	0
Research and development	12	11	13	14	14	17	16	17
Selling, general and administrative	6	6	6	6	7	7	6	6
Operating income	−16	−17	−19	−19	−20	7	−22	−22
Interest expense	0	0	—	—	—	—	—	—
Net income	−15	−16	−19	−19	−21	6	−21	−24
Diluted EPS	−$0.41	−$0.43	−$0.49	−$0.50	−$0.40	$0.26	−$0.33	−$0.38
EBITDA	−16	−17	−19	−19	−20	7	−22	−22

EBITDA is operating income plus depreciation and amortisation. EPS and share counts are restated for stock splits. A dash means the company did not report the line for that period; expense lines are shown as reported, so they need not add up to the totals when a company reports other items between them.

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Figures from Orchestra Biomed Holdings, Inc.'s SEC filings (10-K and 10-Q), retrieved October 29, 2026. How we read and check them: methodology and data sources. Not investment advice. Back to Orchestra Biomed Holdings, Inc.