Pyxis Oncology, Inc.: which funds bought and sold

Institutions that bought and sold Pyxis Oncology shares in Q2 2026, from the holdings they reported to the SEC on Form 13F for March 31, 2026 and June 30, 2026.

Between March 31, 2026 and June 30, 2026, 31 institutions that filed 13F reports for both quarters added to or opened positions in Pyxis Oncology, and 34 cut or closed them. Together they added a net 5.8M shares, +21.2% on what they held at the start of the quarter. Active managers and hedge funds on our list were net buyers of 173K shares (+2.0%); index fund managers were net buyers of 139K shares (+3.4%). 9 opened a new position and 10 sold out entirely.

Bought, Q2 2026 31 institutions, 9 of them new holders Sold, Q2 2026 34 institutions, 10 of them sold out

Net change, all compared +5.8M shares (+21.2%)

Net change, active managers +173K shares (+2.0%), 8 bought, 12 sold

Buyers versus sellers

institutions compared, 84

31 bought 19 34 sold

Active managers and hedge funds 8 bought · 12 sold · +173K

Index fund managers 4 bought · 1 sold · +139K

Other institutions 19 bought · 21 sold · +5.5M

Biggest buyers

by change in shares held

Biggest buyers
Institution	Change in shares	Shares June 30, 2026	Value
Gordonmd Global Investments LP	+5.9M +143.2%	10.0M	$30.2M
Woodline Partners LP Hedge fund	+524K New position	524K	$1.6M
Marshall Wace, LLP Hedge fund	+476K +134.3%	831K	$2.5M
Blackrock, Inc. Index funds	+79K +10.0%	868K	$2.6M
Bank Of America Corp	+64K +378.8%	80K	$242,197
Myda Advisors LLC	+50K New position	50K	$150,500
Quadrature Capital Ltd Hedge fund	+47K New position	47K	$141,672
Verdad Advisers, LP	+45K New position	45K	$135,146
Vanguard Capital Management LLC Index funds	+42K +2.1%	2.1M	$6.2M
Qube Research & Technologies Ltd Hedge fund	+39K +342.4%	50K	$150,295
Simplex Trading, LLC	+38K +14881.0%	38K	$114,085
Walleye Capital LLC Hedge fund	+37K New position	37K	$110,702
Citigroup Inc	+36K +2095.7%	38K	$114,997
Mackenzie Financial Corp	+26K New position	26K	$79,292
Northern Trust Corp Index funds	+22K +21.6%	124K	$373,117
Stifel Financial Corp	+20K +39.4%	70K	$212,015
Group One Trading LLC	+16K New position	16K	$49,605
Two Sigma Investments, LP Hedge fund	+11K +14.5%	84K	$252,723
Dimensional Fund Advisors LP	+10K +39.6%	36K	$108,887
LPL Financial LLC	+10K +29.8%	44K	$131,098

Biggest buyers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
Woodline Partners LP Hedge fund	+524K New position	524K	$1.6M
Marshall Wace, LLP Hedge fund	+476K +134.3%	831K	$2.5M
Quadrature Capital Ltd Hedge fund	+47K New position	47K	$141,672
Qube Research & Technologies Ltd Hedge fund	+39K +342.4%	50K	$150,295
Walleye Capital LLC Hedge fund	+37K New position	37K	$110,702
Two Sigma Investments, LP Hedge fund	+11K +14.5%	84K	$252,723
Point72 Asset Management, L.P. Hedge fund	+5,086 +15.9%	37K	$111,647
FMR LLC Active manager	+471 +4.0%	12K	$37,274

Biggest sellers

by change in shares held

Biggest sellers
Institution	Change in shares	Shares June 30, 2026	Value
683 Capital Management, LLC Hedge fund	−437K −48.7%	459K	$1.4M
Millennium Management LLC Hedge fund	−165K −41.4%	233K	$701,342
Longaeva Partners L.P.	−150K −29.7%	354K	$1.1M
Palo Alto Investors LP	−146K −14.5%	864K	$2.6M
Renaissance Technologies LLC Hedge fund	−116K −13.1%	772K	$2.3M
UBS Group AG	−99K −38.9%	155K	$467,203
Laurion Capital Management LP Hedge fund	−96K −1.9%	4.9M	$14.8M
Xtx Topco Ltd	−89K −44.6%	111K	$333,926
Panagora Asset Management Inc Active manager	−69K Sold out	0	—
Toronto Dominion Bank	−50K Sold out	0	—
Barclays PLC	−45K −90.6%	4,669	$14,054
Susquehanna International Group, LLP	−41K Sold out	0	—
Morgan Stanley	−36K −52.0%	33K	$100,679
Jacobs Levy Equity Management, Inc Active manager	−32K −7.0%	429K	$1.3M
Maia Wealth LLC	−21K Sold out	0	—
Catalyst Funds Management Pty Ltd	−20K Sold out	0	—
Squarepoint Ops LLC Hedge fund	−18K Sold out	0	—
Acadian Asset Management LLC Active manager	−17K −12.1%	127K	$380,000
Jane Street Group, LLC	−14K −4.7%	290K	$873,171
Citadel Advisors LLC Hedge fund	−14K −22.7%	47K	$142,424

Biggest sellers, active managers and hedge funds
Institution	Change in shares	Shares June 30, 2026	Value
683 Capital Management, LLC Hedge fund	−437K −48.7%	459K	$1.4M
Millennium Management LLC Hedge fund	−165K −41.4%	233K	$701,342
Renaissance Technologies LLC Hedge fund	−116K −13.1%	772K	$2.3M
Laurion Capital Management LP Hedge fund	−96K −1.9%	4.9M	$14.8M
Panagora Asset Management Inc Active manager	−69K Sold out	0	—
Jacobs Levy Equity Management, Inc Active manager	−32K −7.0%	429K	$1.3M
Squarepoint Ops LLC Hedge fund	−18K Sold out	0	—
Acadian Asset Management LLC Active manager	−17K −12.1%	127K	$380,000
Citadel Advisors LLC Hedge fund	−14K −22.7%	47K	$142,424
Balyasny Asset Management L.P. Hedge fund	−743 Sold out	0	—

New positions

largest by value

Institution	Shares	Value June 30, 2026
Woodline Partners LPHedge fund	524K	$1.6M
Myda Advisors LLC	50K	$150,500
Quadrature Capital LtdHedge fund	47K	$141,672
Verdad Advisers, LP	45K	$135,146
Walleye Capital LLCHedge fund	37K	$110,702
Mackenzie Financial Corp	26K	$79,292
Group One Trading LLC	16K	$49,605
Federation Des Caisses Desjardins Du Quebec	4,500	$13,545
First United Bank & Trust	2,500	$7,375

Sold out

largest by value

Institution	Shares	Value March 31, 2026
Panagora Asset Management IncActive manager	69K	$101,359
Toronto Dominion Bank	50K	$73,000
Susquehanna International Group, LLP	41K	$60,153
Maia Wealth LLC	21K	$31,064
Catalyst Funds Management Pty Ltd	20K	$29,784
Squarepoint Ops LLCHedge fund	18K	$25,604
Two Sigma Securities, LLC	13K	$19,672
Royal Bank Of Canada	5,839	$9,000
Balyasny Asset Management L.P.Hedge fund	743	$1,085
Ascentis Independent Advisors	10	$14

Who holds the shares

13F holdings at June 30, 2026

Institutions reporting: 76
Ten largest holders: 84.7%
Index fund managers: 12.3%
Active managers and hedge funds: 25.6%

Buying and selling by type of institution, March 31, 2026 to June 30, 2026
Type	Bought	Sold	New	Sold out	Net change in shares	Net %
Active managers and hedge funds	8	12	3	3	+173K	+2.0%
Index fund managers	4	1	0	0	+139K	+3.4%
Other institutions	19	21	6	7	+5.5M	+37.4%

Active managers and hedge funds: a list we maintain of about 400 well-known stock-picking firms and hedge funds, matched by SEC registration number (CIK) and checked against the filer names each quarter. Index fund managers: the large index houses, such as BlackRock, Vanguard, State Street, Geode and Northern Trust. Every other filer (banks, brokers, wealth managers, pension funds, insurers and firms not on the list) counts as another institution. A firm that files under several SEC registrations appears once for each.

What these filings can and cannot tell you

Form 13F lists the long positions in US-listed shares held by investment managers with more than $100 million in such holdings. Managers file it up to 45 days after each quarter ends, so this page shows what funds held at the end of each quarter, not what they are doing now: a position may have changed since. Short positions, most derivatives and smaller managers are not included, and a cut can mean a fund lost clients or rebalanced rather than a view on Pyxis Oncology.

Only managers that filed a holdings report for both quarters are compared (84 here). 3 other holders are left out: first-time or late filers, firms that changed their SEC registration, and filings that withheld positions under confidential treatment, any of which would otherwise look like a new position or a sale. Figures are as reported by each manager in the SEC's quarterly 13F data sets; option positions are excluded.

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