Tyra Biosciences, Inc.: which funds bought and sold
Institutions that bought and sold Tyra Biosciences shares in Q2 2026, from the holdings they reported to the SEC on Form 13F for March 31, 2026 and June 30, 2026.
Between March 31, 2026 and June 30, 2026, 102 institutions that filed 13F reports for both quarters added to or opened positions in Tyra Biosciences, and 69 cut or closed them. Together they added a net 2.7M shares, +4.4% on what they held at the start of the quarter. Active managers and hedge funds on our list were net sellers of 894K shares (−2.7%); index fund managers were net buyers of 2.8M shares (+46.3%). 30 opened a new position and 25 sold out entirely.
Bought, Q2 2026 102 institutions, 30 of them new holders Sold, Q2 2026 69 institutions, 25 of them sold out
Net change, all compared +2.7M shares (+4.4%)
Net change, active managers −894K shares (−2.7%), 26 bought, 25 sold
Buyers versus sellers
102 bought 20 69 sold
Active managers and hedge funds 26 bought · 25 sold · −894K
Index fund managers 11 bought · 0 sold · +2.8M
Other institutions 65 bought · 44 sold · +785K
Biggest buyers
| Institution | Change in shares | Shares June 30, 2026 | Value |
|---|---|---|---|
| Price T Rowe Associates Inc Active manager | +1.8M +182.2% | 2.8M | $88.9M |
| FMR LLC Active manager | +1.2M +15.1% | 8.9M | $285M |
| Hood River Capital Management LLC | +1.0M New position | 1.0M | $32.5M |
| State Street Corp Index funds | +924K +76.0% | 2.1M | $68.4M |
| Blackrock, Inc. Index funds | +814K +36.7% | 3.0M | $96.8M |
| Siren, L.L.C. | +725K New position | 725K | $23.2M |
| Deerfield Management Company, L.P. Hedge fund | +468K +85.2% | 1.0M | $32.5M |
| Marshall Wace, LLP Hedge fund | +385K +194.9% | 583K | $18.6M |
| Vanguard Capital Management LLC Index funds | +382K +34.0% | 1.5M | $48.2M |
| Defilade Capital Management, L.P. | +377K New position | 377K | $12M |
| Two Sigma Investments, LP Hedge fund | +348K +342.6% | 450K | $14.4M |
| Walleye Capital LLC Hedge fund | +329K +1758.9% | 348K | $11.1M |
| Geode Capital Management, LLC Index funds | +312K +47.4% | 971K | $31M |
| Qube Research & Technologies Ltd Hedge fund | +267K New position | 267K | $8.5M |
| Citadel Advisors LLC Hedge fund | +263K +1707.7% | 278K | $8.9M |
| Stempoint Capital LP | +246K +63.8% | 633K | $20.2M |
| Morgan Stanley | +180K +149.3% | 300K | $9.6M |
| Franklin Resources Inc Active manager | +179K +1383.0% | 192K | $6.1M |
| Adage Capital Partners Gp, L.L.C. Hedge fund | +162K New position | 162K | $5.2M |
| Vanguard Portfolio Management LLC Index funds | +156K +63.0% | 403K | $12.9M |
| Institution | Change in shares | Shares June 30, 2026 | Value |
|---|---|---|---|
| Price T Rowe Associates Inc Active manager | +1.8M +182.2% | 2.8M | $88.9M |
| FMR LLC Active manager | +1.2M +15.1% | 8.9M | $285M |
| Deerfield Management Company, L.P. Hedge fund | +468K +85.2% | 1.0M | $32.5M |
| Marshall Wace, LLP Hedge fund | +385K +194.9% | 583K | $18.6M |
| Two Sigma Investments, LP Hedge fund | +348K +342.6% | 450K | $14.4M |
| Walleye Capital LLC Hedge fund | +329K +1758.9% | 348K | $11.1M |
| Qube Research & Technologies Ltd Hedge fund | +267K New position | 267K | $8.5M |
| Citadel Advisors LLC Hedge fund | +263K +1707.7% | 278K | $8.9M |
| Franklin Resources Inc Active manager | +179K +1383.0% | 192K | $6.1M |
| Adage Capital Partners Gp, L.L.C. Hedge fund | +162K New position | 162K | $5.2M |
Biggest sellers
| Institution | Change in shares | Shares June 30, 2026 | Value |
|---|---|---|---|
| Farallon Capital Management, L.L.C. Hedge fund | −3.6M Sold out | 0 | — |
| Logos Global Management LP Hedge fund | −850K Sold out | 0 | — |
| Barclays PLC | −813K −97.6% | 20K | $647,585 |
| Commodore Capital LP Hedge fund | −600K −24.2% | 1.9M | $59.9M |
| Nextech Invest Ltd. | −502K −12.4% | 3.6M | $114M |
| Bvf Inc | −500K −25.3% | 1.5M | $47.1M |
| Caligan Partners LP Hedge fund | −470K −36.8% | 807K | $25.8M |
| Balyasny Asset Management L.P. Hedge fund | −351K Sold out | 0 | — |
| Elmind Capital, LP | −330K −94.3% | 20K | $638,800 |
| Paradigm Biocapital Advisors LP | −226K −11.0% | 1.8M | $58.4M |
| Seven Fleet Capital Management LP | −196K Sold out | 0 | — |
| Jennison Associates LLC Active manager | −181K −28.7% | 451K | $14.4M |
| Sofinnova Investments, Inc. | −172K −84.2% | 32K | $1M |
| Ameriprise Financial Inc | −128K −88.3% | 17K | $540,425 |
| Boothbay Fund Management, LLC Hedge fund | −100K −36.5% | 174K | $5.5M |
| Goldman Sachs Group Inc | −87K −15.8% | 463K | $14.8M |
| Invesco Ltd. | −84K −77.2% | 25K | $795,083 |
| Schonfeld Strategic Advisors LLC Hedge fund | −80K Sold out | 0 | — |
| Jacobs Levy Equity Management, Inc Active manager | −73K −45.0% | 89K | $2.8M |
| Cinctive Capital Management LP Hedge fund | −68K −86.9% | 10K | $325,277 |
| Institution | Change in shares | Shares June 30, 2026 | Value |
|---|---|---|---|
| Farallon Capital Management, L.L.C. Hedge fund | −3.6M Sold out | 0 | — |
| Logos Global Management LP Hedge fund | −850K Sold out | 0 | — |
| Commodore Capital LP Hedge fund | −600K −24.2% | 1.9M | $59.9M |
| Caligan Partners LP Hedge fund | −470K −36.8% | 807K | $25.8M |
| Balyasny Asset Management L.P. Hedge fund | −351K Sold out | 0 | — |
| Jennison Associates LLC Active manager | −181K −28.7% | 451K | $14.4M |
| Boothbay Fund Management, LLC Hedge fund | −100K −36.5% | 174K | $5.5M |
| Schonfeld Strategic Advisors LLC Hedge fund | −80K Sold out | 0 | — |
| Jacobs Levy Equity Management, Inc Active manager | −73K −45.0% | 89K | $2.8M |
| Cinctive Capital Management LP Hedge fund | −68K −86.9% | 10K | $325,277 |
New positions
| Institution | Shares | Value June 30, 2026 |
|---|---|---|
| Hood River Capital Management LLC | 1.0M | $32.5M |
| Siren, L.L.C. | 725K | $23.2M |
| Defilade Capital Management, L.P. | 377K | $12M |
| Qube Research & Technologies LtdHedge fund | 267K | $8.5M |
| Adage Capital Partners Gp, L.L.C.Hedge fund | 162K | $5.2M |
| Lord, Abbett & Co. LLC | 122K | $3.9M |
| Orbimed Advisors LLC | 102K | $3.3M |
| Sei Investments Co | 67K | $2.1M |
| Verdad Advisers, LP | 36K | $1.1M |
| Engineers Gate Manager LPHedge fund | 32K | $1M |
Sold out
| Institution | Shares | Value March 31, 2026 |
|---|---|---|
| Farallon Capital Management, L.L.C.Hedge fund | 3.6M | $137M |
| Logos Global Management LPHedge fund | 850K | $32.6M |
| Balyasny Asset Management L.P.Hedge fund | 351K | $13.5M |
| Seven Fleet Capital Management LP | 196K | $7.5M |
| Schonfeld Strategic Advisors LLCHedge fund | 80K | $3M |
| Catalio Capital Management, LP | 67K | $2.6M |
| Vestal Point Capital, LPHedge fund | 54K | $2.1M |
| American Century Companies IncActive manager | 48K | $1.8M |
| Point72 Asset Management, L.P.Hedge fund | 39K | $1.5M |
| Brevan Howard Capital Management LPHedge fund | 39K | $1.5M |
Who holds the shares
- Institutions reporting
- 169
- Ten largest holders
- 66.2% of 13F-reported shares
- Index fund managers
- 12.9% of 13F-reported shares
- Active managers and hedge funds
- 46.2% of 13F-reported shares
| Type | Bought | Sold | New | Sold out | Net change in shares | Net % |
|---|---|---|---|---|---|---|
| Active managers and hedge funds | 26 | 25 | 9 | 14 | −894K | −2.7% |
| Index fund managers | 11 | 0 | 0 | 0 | +2.8M | +46.3% |
| Other institutions | 65 | 44 | 21 | 11 | +785K | +3.4% |