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Tyra Biosciences, Inc. (TYRA) stock

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NASDAQ: TYRA Nasdaq Biotechnology Next results ~November 4, 2026

Tyra Biosciences, Inc. is a US-listed company in the biotechnology industry. Its financial year ends in December.

Who’s trading

What company insiders, investment funds and members of Congress have been doing with the stock, from their own filings.

  • Insiders1 buying, 3 selling1 purchase and 14 sales by directors and officers, last 12 monthsInsider trades
  • Funds102 adding, 69 cuttingOf 51 active managers that changed their stake, 26 added; quarter to June 30, 2026Fund buyers and sellers

The Fundamentalytics view

Next results ~November 4, 2026 (estimated)

Assembled from SEC-filed figures — the full workings are on this page and in our methodology. Observations, not recommendations.

Strengths

Nothing in Tyra Biosciences, Inc.'s latest figures clears our strength thresholds.

Things to watch

  • Results due soon. Results are expected around 4 November; the share price can move sharply on the day.
  • Volatile shares. Over the past year the shares showed annualised volatility of 67% and a beta of 0.5 against the S&P 500.
  • Heavily shorted. 22.9% of the shares available to trade are sold short (10.9 days of average volume to cover).
  • Missing expectations. Earnings per share fell short of the consensus estimate in 3 of the last four quarters.

Latest results

Earnings per share
-$0.69 against an average estimate of -$0.64: missed by 7.0%
Share reaction
-19.8% in the first session after the results on August 4, 2026, against +1.6% for the S&P 500
Next report
November 4, 2026; average EPS estimate -$0.67

Tyra Biosciences' figures from its SEC filings and results release; estimates are the analysts' average. Not a recommendation.

Price chart

  • 1 day+1.2%
  • 1 week+4.5%
  • 1 month+4.4%
  • This year-18.9%
  • 1 year+34.7%
  • 5 years-26.3%
  • S&P 500 this year+11.2%

Closing prices to 2026-11-02. Price change only, dividends excluded.

Loading chart…

Third-party market data · may be delayed

At a glance

Trailing twelve months, from SEC filings

Earnings

Last results
August 4, 2026
Next results (est.)
November 4, 2026

News & updates

Updated October 31, 2026

Company announcements, filed results and changes that matter to shareholders.

  1. Announcement
  2. Announcement
  3. Results

Refreshed hourly when new source data is available. Summaries are checked against company releases and SEC filings. Company announcement headlines are labelled when a checked summary is unavailable.

No model value for Tyra Biosciences, Inc. at the moment. Current status: limited reported history: available models are shown without a Buy/Hold/Sell rating. Available reported financials are shown below.

Fundamentalytics rating

model v1.6 · 2026-11-03

Not rated: limited reported history: available models are shown without a Buy/Hold/Sell rating.

Valuation models

We value Tyra Biosciences, Inc. as an operating company, with every model that fits that kind of business. Cost of equity 10.5%: the 10-year Treasury yield (4.9%) plus a beta of 1.23 times a 4.5% equity risk premium.

Value per share by model
Model Value per share In the combined value?
Price-to-earnings vs peers Earnings per share times peers' typical (harmonic-mean) price-to-earnings. — Does not apply: no twelve-month earnings or share count in the filings yet
Residual income Book value plus the present value of returns above the cost of equity, fading over ten years. — Does not apply: no twelve-month earnings or share count in the filings yet
Justified price-to-book Book value times (return on equity - growth) / (cost of equity - growth): steady-state returns. — Does not apply: no twelve-month earnings or share count in the filings yet
Revenue-to-maturity model Revenue grown to maturity with the cash margin moving to the industry's; for companies not yet profitable. — Does not apply: revenue and margins don't support a positive value
Price-to-sales vs peers Sales per share times peers' typical price-to-sales; used only when earnings are negative. — Does not apply: no twelve-month earnings or share count in the filings yet
Combined value Weighted average of the models that apply: the primary model (price-to-earnings vs peers) counts double. Models more than 5x or less than 0.2x the share price, or more than 3x away from the other models' median, are left out. — No model applies: the filings don’t yet support a value.

Different models fail in different ways, so where several apply we average them rather than trust one. Peer-based models compare Tyra Biosciences, Inc. with Biotechnology in our coverage, using third-party market data. Model values are estimates under stated assumptions, updated as new filings arrive; not price targets or investment advice. How each model works.

Moat

Not assessed: fewer than five years of comparable figures in the filings. AI disruption exposure for this industry: Medium.

A rules-based reading of reported figures, not a forecast and not investment advice. How the score is built: methodology.

Forecasts and guidance

Next results: November 4, 2026, after the close. Analysts expect revenue of $0 and EPS of −$0.67 (range −$0.76 to −$0.47) for the quarter.

Analysts' consensus

Tyra Biosciences, Inc.: consensus estimates
Fiscal yearEPSGrowthRevenueGrowth
Current −$2.64 −31% — 0%
Next −$2.77 −5% — 0%

How the EPS forecast has moved

The consensus EPS forecast for the current fiscal year is +2.2% on 90 days ago. In the last 30 days, 4 analysts raised Tyra Biosciences, Inc.'s forecast and 0 cut it.

Consensus EPS forecast Tyra Biosciences, Inc., last 90 days
−$3.00 −$2.00 −$1.00 $0.00 90 days ago 60 days ago 30 days ago 7 days ago Now Current fiscal year, 90 days ago: −$2.58 Current fiscal year, 60 days ago: −$2.67 Current fiscal year, 30 days ago: −$2.66 Current fiscal year, 7 days ago: −$2.64 Current fiscal year, Now: −$2.64 −$2.64 Next fiscal year, 90 days ago: −$2.82 Next fiscal year, 60 days ago: −$2.96 Next fiscal year, 30 days ago: −$2.87 Next fiscal year, 7 days ago: −$2.77 Next fiscal year, Now: −$2.77 −$2.77

Average of analysts' published estimates (third-party data).

View chart data
Period Current fiscal yearNext fiscal year
90 days ago −$2.58−$2.82
60 days ago −$2.67−$2.96
30 days ago −$2.66−$2.87
7 days ago −$2.64−$2.77
Now −$2.64−$2.77

Earnings against estimates

Tyra Biosciences, Inc.: reported EPS against the consensus estimate
Quarter toEstimateActualSurprise
Jun 2026 −$0.64 −$0.69 −7.0%
Mar 2026 −$0.59 −$0.64 −8.6%
Dec 2025 −$0.53 −$0.57 −8.5%
Sept 2025 −$0.51 −$0.50 +2.0%

Adjusted EPS as companies report it, against the average analyst estimate.

Analyst recommendations

15 analysts, Oct 2026
Buy1493%
Hold17%
Sell00%

Monthly trend

  1. Oct 202621215
  2. Sep 202621215
  3. Aug 202621215
  4. Jul 202621215

Counts of recommendations published by analysts covering Tyra Biosciences, Inc., by month. Source: Aggregated broker recommendations (third-party data). Aggregated counts only: we do not reproduce any firm's recommendation or price target, and these are not Fundamentalytics ratings.

Positioning

Short interest
22.9%
of tradable shares
Days to cover
10.93
at average volume
Short interest, 1 month
−4%
to October 15, 2026
Held by institutions
—
of shares
Held by insiders
2.4%
of shares
Employees
87
full time

Consensus figures average analysts' published estimates (third-party data); guidance is the company's own. Neither is our forecast. Short interest is reported twice a month and lags. Market data may be delayed.

This section is general information, not investment advice or a personal recommendation, and it does not take account of your objectives or circumstances. Forecasts and guidance are estimates, not promises: companies miss their own guidance and analysts' figures are often revised. Prices can fall as well as rise, and you can lose money. See our disclaimer.

Share-price performance

Market data may be delayed

Recent prices are available. Older price history and the statistics that need it are being loaded in the background.

Return and risk by year

Tyra Biosciences, Inc.: yearly return, monthly win rate and worst fall against the S&P 500
Calendar year 20222023202420252026 to date
Return
TYRA−46%+82%+0%+89%−19%
Industry peers (median)−57%−18%−29%−5%−27%
S&P 500−18%+26%+25%+18%+11%
Months that ended higher
TYRA42%67%42%75%36%
S&P 50042%67%75%75%46%
Largest fall from a high during the year
TYRA−63%−37%−51%−58%−53%
S&P 500−25%−10%−8%−19%−9%

Worst fall since September 15, 2021: 83% from November 4, 2021 to June 17, 2022. Getting back needed a 496% gain, reached on January 27, 2026, 1320 days after the low.

Price behaviour

52-week range
$14.28 – $39.61
From 52-week high
−46.1%
vs 50-day average
−5.5%
vs 200-day average
−28.5%
Volatility (1 year)
67%
Beta vs S&P 500
0.48

Volatility is the annualised standard deviation of daily returns. Beta 1.5 means the shares typically moved 1.5% for each 1% move in the S&P 500 over the past year. Prices to November 2, 2026.

Share price after results

Next day
4 up, 8 down
typical move ±5.8%
After a week
6 up, 6 down
typical move ±7.3%
After a month
8 up, 4 down
typical move ±13.5%
Tyra Biosciences, Inc.: share-price change after each results release
Results releasedNext dayS&P 500 next day5 days21 days
August 4, 2026 −19.8% +1.6% −21.4% −21.6%
May 13, 2026 +4.7% +1.4% −4.2% −22.6%
March 2, 2026 −0.9% −0.8% +1.3% +15.0%
November 5, 2025 −4.8% −0.7% +3.2% +43.3%
August 14, 2025 −0.2% −0.2% +8.8% +14.5%
May 8, 2025 +10.5% +0.6% +8.0% +12.4%
March 27, 2025 −4.6% −2.3% −18.9% +1.0%
November 7, 2024 −5.9% +1.2% −4.6% −6.5%
August 7, 2024 +0.7% +1.6% +6.8% +1.9%
May 9, 2024 −3.8% +0.7% +5.9% +10.9%
March 19, 2024 +7.0% +1.5% −0.5% −9.7%
November 7, 2023 −6.2% +0.4% −3.7% +2.5%

From the close before the release date to the close 1, 5 and 21 trading days after it, so releases before the open and after the close are both captured. Past moves don't predict future ones.

Fundamentals

Data: SEC EDGAR XBRL company facts (as filed in 10-K/10-Q); forms . Generated November 3, 2026. Definitions in our methodology.

Reported value
$2.2B
Institutions reporting
169
Shares held vs prior quarter
▲ 4.9%
Positions opened / closed
30 / 25

Top buyers and sellers, Q2 2026: 102 institutions bought and 69 sold ; the biggest buyer was Price T Rowe Associates Inc (+1.8M shares) and the biggest seller Farallon Capital Management, L.L.C (−3.6M). See which funds bought and sold →

Largest reported holders, June 30, 2026
Manager Value Shares Share of 13F value Shares QoQ
RA Capital Management, L.P. $390M 12.2M 17.6% 0.0%
FMR LLC $285M 8.9M 12.8% ▲ 15.1%
Jupiter Topco LLC $139M 4.4M 6.3% —
Alta Partners Management Company, L.P. $122M 3.8M 5.5% 0.0%
Nextech Invest Ltd. $114M 3.6M 5.1% ▼ 12.4%
Tcg Crossover Management, LLC $104M 3.2M 4.7% 0.0%
Blackrock, Inc. $96.8M 3.0M 4.4% ▲ 36.7%
Price T Rowe Associates Inc $88.9M 2.8M 4.0% ▲ 182.2%
State Street Corp $68.4M 2.1M 3.1% ▲ 76.0%
Commodore Capital LP $59.9M 1.9M 2.7% ▼ 24.2%
Paradigm Biocapital Advisors LP $58.4M 1.8M 2.6% ▼ 11.0%
Vanguard Capital Management LLC $48.2M 1.5M 2.2% ▲ 34.0%

From Form 13F filings with the SEC ( quarterly data sets), as reported by each manager for June 30, 2026 and filed up to 45 days later. 13F reports cover long US-listed positions of managers above $100M only, so this is not Tyra Biosciences, Inc.'s complete shareholder register. Values are as reported by the filers ; 1 inconsistently scaled filing rows were excluded.

Insider trading activity

Full insider history and chart
Recent insider open-market transactions
Insider Date Trade Shares Price Value
Verjee Rehan Director September 9, 2026 Buy 972 $20.58 $20,001
Kaplan Gilla Director March 25, 2026 Sell 14,295 $36.97 $528,486
Bensen Daniel Chief Discovery Officer February 12, 2026 Sell pre-set plan 5,872 $33.37 $195,949
Bensen Daniel Chief Discovery Officer February 12, 2026 Sell pre-set plan 2,128 $31.50 $67,032
Bensen Daniel Chief Discovery Officer January 12, 2026 Sell pre-set plan 1,017 $29.08 $29,574
Bensen Daniel Chief Discovery Officer January 12, 2026 Sell pre-set plan 6,983 $28.44 $198,597
More Robert J Director December 19, 2025 Sell pre-set plan 10,000 $25.00 $250,000
Bensen Daniel Chief Discovery Officer December 12, 2025 Sell pre-set plan 8,000 $22.64 $181,120
More Robert J Director November 21, 2025 Sell pre-set plan 246,871 $20.25 $5M
Bensen Daniel Chief Operating Officer November 19, 2025 Sell pre-set plan 49,956 $16.32 $815,282
Bensen Daniel Chief Operating Officer November 18, 2025 Sell pre-set plan 75,633 $16.07 $1.2M
Bensen Daniel Chief Operating Officer November 17, 2025 Sell pre-set plan 18,572 $16.11 $299,195

From insiders' Form 4 filings with the SEC. Excludes awards, option exercises and shares withheld for tax. "Pre-set plan" means the filing marks the trade as made under a Rule 10b5-1 plan. See every insider trade since five years ago, on a price chart.

Earnings dates and SEC filings

Results announcements

Next expected around November 4, 2026 estimated from the company's past filing pattern, not announced

  • August 4, 2026
  • May 13, 2026
  • March 2, 2026
  • November 5, 2025
  • August 14, 2025
  • May 8, 2025

Recent SEC filings

Data status

When each part of this page on Tyra Biosciences, Inc. was last updated.

DataLast updatedSource
Share priceExchange closing prices
News and updatesCompany releases and SEC 8-K filings
Analyst estimatesAggregated analyst estimates
Valuation and scoresOur models, from the filed figures

How we build and check these figures: methodology and data sources.

Tyra Biosciences, Inc. in brief

What does Tyra Biosciences, Inc. do?
Tyra Biosciences, Inc. is a US-listed company in the biotechnology industry. Its financial year ends in December.
What is Tyra Biosciences, Inc.'s stock ticker?
Tyra Biosciences, Inc. trades under the ticker TYRA on Nasdaq. This page brings together its financial statements, valuation models, ownership and recent company updates.
Who are Tyra Biosciences, Inc.'s largest institutional shareholders?
By value reported in 13F filings for June 30, 2026, the largest reported holders are RA Capital Management, L.P., FMR LLC and Jupiter Topco LLC. 13F reports cover long US-listed positions of managers above $100M, filed up to 45 days after quarter end.
Are insiders buying or selling Tyra Biosciences, Inc. stock?
Over the last 12 months, Tyra Biosciences, Inc.'s directors and officers reported 1 open-market purchases and 14 sales on Form 4. The insider trading page charts every trade.
When is Tyra Biosciences, Inc.'s next earnings date?
Around November 4, 2026, estimated from the spacing of its past results announcements (8-K filings). That is an estimate, not a confirmed date — Tyra Biosciences, Inc. announces its own schedule.