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Alnylam Pharmaceuticals vs Neurocrine Biosciences

Alnylam Pharmaceuticals is the larger business, with $3.71bn of revenue in fiscal 2025 against $2.86bn for Neurocrine Biosciences (1.3 times as much). Alnylam Pharmaceuticals grew faster (65.2% against 21.4%). Neurocrine Biosciences kept more of each dollar of sales as profit: a net margin of 16.7% against 8.4%. Neurocrine Biosciences carries less debt relative to equity (0.0% against 127.7%).

Latest fiscal yearAlnylam PharmaceuticalsALNY, 2025Neurocrine BiosciencesNBIX, 2025
Revenue $3.71bn $2.86bn
Revenue growth 65.2% 21.4%
Net income $314m $479m
Operating margin 13.5% 21.6%
Net margin 8.4% 16.7%
Return on equity 73.3% 16.4%
Free cash flow $465m $749m
Cash $1.66bn $713m
Total debt $1.01bn $0
Debt to equity 127.7% 0.0%
Dividend per share — —
Dividend yield — —
Share buybacks — $168m
Employees 2,500 1,800
Market value $21.46bn $16.93bn
Price vs our value range Above our value range Below our value range
Moat score 33 (Weak) 61 (Moderate)
Insider trades, 12 months 0 buys, 279 sales 0 buys, 40 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

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Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.