undamentalytics Newsletter

Beam Therapeutics vs Karyopharm Therapeutics

Beam Therapeutics and Karyopharm Therapeutics are similar in size: $140m and $146m of revenue in their latest fiscal years. Beam Therapeutics grew faster (120.0% against 0.6%). Beam Therapeutics kept more of each dollar of sales as profit: a net margin of -57.2% against -134.2%.

Latest fiscal yearBeam TherapeuticsBEAM, 2025Karyopharm TherapeuticsKPTI, 2025
Revenue $140m $146m
Revenue growth 120.0% 0.6%
Net income −$80.0m −$196m
Operating margin -274.6% -62.1%
Net margin -57.2% -134.2%
Return on equity -8.1% —
Free cash flow −$360m −$75.4m
Cash $295m $60.5m
Total debt $0 $94.8m
Debt to equity 0.0% —
Dividend per share — —
Dividend yield — —
Share buybacks — —
Employees 511 228
Market value $2.74bn $2.0m
Price vs our value range — —
Moat score 9 (Weak) 8 (Weak)
Insider trades, 12 months 0 buys, 31 sales 0 buys, 21 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

Go deeper

Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.