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Bolt Biotherapeutics vs Prime Medicine

Bolt Biotherapeutics is the larger business, with $7.7m of revenue in fiscal 2025 against $4.6m for Prime Medicine (1.7 times as much). Prime Medicine grew faster (55.3% against 0.1%). Bolt Biotherapeutics kept more of each dollar of sales as profit: a net margin of -433.7% against -4342.4%. Bolt Biotherapeutics carries less debt relative to equity (0.0% against 0.0%).

Latest fiscal yearBolt BiotherapeuticsBOLT, 2025Prime MedicinePRME, 2025
Revenue $7.7m $4.6m
Revenue growth 0.1% 55.3%
Net income −$33.4m −$201m
Operating margin -469.3% -4498.1%
Net margin -433.7% -4342.4%
Return on equity -79.7% -146.8%
Free cash flow −$39.9m −$167m
Cash $11.7m $63.0m
Total debt $0 $0
Debt to equity 0.0% 0.0%
Dividend per share — —
Dividend yield — —
Share buybacks — —
Employees 23 146
Market value $12.7m $807m
Price vs our value range — —
Moat score 12 (Weak) —
Insider trades, 12 months 4 buys, 9 sales 0 buys, 0 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

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Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.