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Halozyme Therapeutics vs Sarepta Therapeutics

Sarepta Therapeutics is the larger business, with $2.20bn of revenue in fiscal 2025 against $1.40bn for Halozyme Therapeutics (1.6 times as much). Halozyme Therapeutics grew faster (37.6% against 15.6%). Halozyme Therapeutics kept more of each dollar of sales as profit: a net margin of 22.7% against -32.5%.

Latest fiscal yearHalozyme TherapeuticsHALO, 2025Sarepta TherapeuticsSRPT, 2025
Revenue $1.40bn $2.20bn
Revenue growth 37.6% 15.6%
Net income $317m −$713m
Operating margin — -31.8%
Net margin 22.7% -32.5%
Return on equity 153.6% -53.5%
Free cash flow $645m −$307m
Cash $134m $801m
Total debt $2.18bn $829m
Debt to equity — 72.7%
Dividend per share — —
Dividend yield — —
Share buybacks $342m $25.0m
Employees 423 835
Market value $14.77bn $1.96bn
Price vs our value range Below our value range —
Moat score 71 (Strong) 10 (Weak)
Insider trades, 12 months 0 buys, 105 sales 0 buys, 2 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

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Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.