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Alkermes plc. vs Sarepta Therapeutics

Sarepta Therapeutics is the larger business, with $2.20bn of revenue in fiscal 2025 against $1.48bn for Alkermes plc. (1.5 times as much). Sarepta Therapeutics grew faster (15.6% against -5.2%). Alkermes plc. kept more of each dollar of sales as profit: a net margin of 16.4% against -32.5%. Alkermes plc. carries less debt relative to equity (0.0% against 72.7%).

Latest fiscal yearAlkermes plc.ALKS, 2025Sarepta TherapeuticsSRPT, 2025
Revenue $1.48bn $2.20bn
Revenue growth -5.2% 15.6%
Net income $242m −$713m
Operating margin 17.2% -31.8%
Net margin 16.4% -32.5%
Return on equity 14.7% -53.5%
Free cash flow $480m −$307m
Cash $389m $801m
Total debt $0 $829m
Debt to equity 0.0% 72.7%
Dividend per share — —
Dividend yield — —
Share buybacks — $25.0m
Employees 2,050 835
Market value $7.84bn $1.96bn
Price vs our value range Within our value range —
Moat score 63 (Moderate) 10 (Weak)
Insider trades, 12 months 0 buys, 33 sales 0 buys, 2 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

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Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.