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Phathom Pharmaceuticals vs Syndax Pharmaceuticals

Phathom Pharmaceuticals and Syndax Pharmaceuticals are similar in size: $175m and $172m of revenue in their latest fiscal years. Syndax Pharmaceuticals grew faster (627.8% against 216.9%). Phathom Pharmaceuticals kept more of each dollar of sales as profit: a net margin of -126.3% against -165.6%.

Latest fiscal yearPhathom PharmaceuticalsPHAT, 2025Syndax PharmaceuticalsSNDX, 2025
Revenue $175m $172m
Revenue growth 216.9% 627.8%
Net income −$221m −$285m
Operating margin -91.4% -158.4%
Net margin -126.3% -165.6%
Return on equity — -161.8%
Free cash flow −$167m −$323m
Cash $130m $135m
Total debt $209m $350m
Debt to equity — 541.5%
Dividend per share — —
Dividend yield — —
Share buybacks — —
Employees 371 298
Market value $449m $1.29bn
Price vs our value range — —
Moat score — 8 (Weak)
Insider trades, 12 months 0 buys, 1 sales 0 buys, 10 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

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Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.