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Arrowhead Pharmaceuticals, Inc. key statistics and ratios

In fiscal 2025, Arrowhead Pharmaceuticals, Inc. had return on equity of -0.5% and a net margin of -0.2%. Each ratio below is calculated from the figures on its income statement, balance sheet and cash flow pages.

Financial ratios

US$ thousands unless shown otherwise. Fiscal years, plus the last twelve months (LTM) when newer.

Arrowhead Pharmaceuticals, Inc.: financial ratios, annual
Fiscal year2011Sept 20112012Sept 20122013Sept 20132014Sept 20142015Sept 20152016Sept 20162017Sept 20172018Sept 20182019Sept 20192020Sept 20202021Sept 20212022Sept 20222023Sept 20232024Sept 20242025Sept 2025LTMJun 2026
Net margin<−999%<−999%<−999%<−999%<−999%<−999%−109.5%−337.3%40.3%−96.1%−101.9%−72.4%−85.3%<−999%−0.2%−47.8%
Return on equity−24.5%−185.3%−166.0%−60.4%−66.5%−79.4%−38.8%−61.5%39.9%−23.9%−32.4%−43.6%−61.3%—−0.5%−68.7%
Return on assets−19.7%−130.3%−115.7%−53.3%−58.4%−62.8%−29.6%−50.5%29.5%−19.4%−22.9%−25.1%−28.2%−62.9%−0.1%−18.3%
Effective tax rate————————0.3%—————41.6%—
R&D as % of revenue>999%>999%>999%>999%>999%>999%162.1%328.1%48.0%146.5%149.2%122.2%146.7%>999%73.2%108.0%

Returns use average equity or assets over the year. Return on equity is left blank when equity is negative or so small that the ratio says nothing (above ±200%); interest cover is left blank above 200 times. Price-based ratios such as P/E are on the valuation page.

Financial health

1 of 2 checks passed · June 30, 2026
What it owns · $2.1bn
Short-term assets $1.7bnLonger-term assets $441m
What it owes, and who funded it · $749m
Short-term liabilities $283mShareholders' equity $466m
  • Short-term assets cover short-term liabilities $1.7bn of assets due within a year against $283m of liabilities due within a year.
  • Short-term assets cover long-term liabilities Not assessable from the reported split. Not assessable.
  • More cash than debt Cash or debt not separately reported. Not assessable.
  • Debt below 40% of shareholders' equity Equity or debt not reported. Not assessable.
  • Debt burden no higher than five years ago Five-year comparison not available. Not assessable.
  • A year's operating cash flow covers at least 20% of debt Cash flow or debt not reported. Not assessable.
  • Operating profit covers interest at least five times over Operating income of −$226m against $93m of interest.

From Arrowhead Pharmaceuticals, Inc.'s latest balance sheet as filed. Checks are fixed, documented rules (methodology), counted only where the company reports the figures — a dot means the filing doesn't break the item out. Descriptions of reported data, not advice.

Moat

10 /100

Weak moat

How hard Arrowhead Pharmaceuticals's competitive advantage looks for rivals to wear away, judged from 10 years of its own filings: returns on capital, pricing power, profit durability, cash conversion and discipline.

  • Returns on capital 0 / 20

    Net income has been a median -18.8% of total assets over 10 years.

  • Durability 10 / 20

    Operating margin has been a median -67.1%; its worst year was -2785.1%.

  • Cash conversion 2 / 20

    Free cash flow was positive in 2 of 10 years, at a median -59.8% of revenue.

  • Discipline 0 / 20

    The diluted share count rose 36.4% over five years; stock-based pay has been a median 42.7% of revenue.

AI disruption exposure: Medium. In this industry, AI could change how the product is made or sold, without replacing the core asset. The score above includes a 5-point deduction for that exposure (15 before it).

A rules-based reading of reported figures, not a forecast and not investment advice. How the score is built: methodology.

Compare with peers

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Figures from Arrowhead Pharmaceuticals, Inc.'s SEC filings (10-K and 10-Q), retrieved October 20, 2026. How we read and check them: methodology and data sources. Not investment advice. Back to Arrowhead Pharmaceuticals, Inc.