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Illumina, Inc. key statistics and ratios

In fiscal 2025, Illumina, Inc. had return on equity of 33.4%, an operating margin of 18.6%, debt equal to 73.0% of equity and a current ratio of 2.08. Each ratio below is calculated from the figures on its income statement, balance sheet and cash flow pages.

Financial ratios

US$ thousands unless shown otherwise. Fiscal years, plus the last twelve months (LTM) when newer.

Illumina, Inc.: financial ratios, annual
Fiscal year2009Jan 20102010Jan 20112011Jan 20122012Dec 20122013Dec 20132014Dec 20142015Jan 20162016Jan 20172017Dec 20172018Dec 20182019Dec 20192020Jan 20212021Jan 20222022Jan 20232023Dec 20232024Dec 20242025Dec 2025LTMSept 2026
Gross margin68.1%66.6%67.2%67.4%64.2%69.7%69.8%69.5%66.4%69.0%69.6%68.0%69.7%64.8%60.9%65.4%66.1%67.9%
Operating margin18.8%23.4%18.9%17.5%9.4%27.7%27.6%24.5%22.0%26.5%27.8%17.9%−2.7%−91.2%−23.7%−19.1%18.6%21.2%
Net margin10.8%13.8%8.2%13.2%8.8%19.0%20.8%19.3%26.4%24.8%28.3%20.3%16.8%−96.1%−25.8%−28.0%19.6%19.7%
Free-cash-flow margin17.9%24.7%26.6%19.4%21.6%21.2%29.0%21.6%20.5%25.4%23.8%27.5%7.4%2.3%6.3%16.2%21.4%23.3%
Return on equity8.4%12.1%7.6%12.6%8.8%23.6%27.9%22.9%29.4%25.4%23.9%14.1%9.9%−50.8%−18.8%−30.1%33.4%30.5%
Return on assets5.1%7.6%4.3%6.4%4.5%11.1%13.1%11.6%15.2%13.5%14.0%8.8%6.7%−32.1%−10.4%−14.9%13.1%13.3%
Asset turnover0.470.550.520.480.510.590.630.600.580.550.500.430.400.330.400.530.670.67
Current ratio2.222.356.815.875.022.623.433.293.992.496.693.602.481.281.661.772.082.63
Debt to equity33.6%26.0%75.1%72.8%61.9%100.5%59.0%48.2%43.4%53.1%24.7%25.2%9.2%41.4%25.9%83.8%73.0%56.9%
Interest cover (operating income ÷ interest)5.3x8.6x5.7x5.3x3.4x12.3x14.3x17.8x16.4x15.5x18.9x11.8xn/mn/mn/mn/m8.0x9.8x
Effective tax rate36.7%32.6%34.9%32.1%21.3%21.3%21.4%23.7%35.0%12.5%11.4%23.4%13.8%———21.7%15.4%
R&D as % of revenue21.1%19.7%18.7%20.1%19.5%20.8%18.1%21.0%19.8%18.7%18.3%21.1%26.2%28.8%30.1%26.7%22.3%21.5%
SG&A as % of revenue26.5%24.4%24.8%24.9%26.8%25.1%23.2%24.4%24.5%23.8%23.6%29.1%46.2%28.3%35.8%25.0%25.0%25.0%
Capital spending as % of revenue7.9%5.5%7.4%6.0%5.6%5.7%6.4%10.8%11.3%8.9%5.9%5.8%4.6%6.2%4.3%2.9%3.4%3.8%
Free cash flow ÷ net income165.4%178.4%323.6%147.5%245.2%111.9%139.2%112.1%77.8%102.4%84.0%135.8%44.2%———109.5%118.1%
Dividends and buybacks ÷ free cash flow146.5%19.8%203.5%37.0%16.3%60.0%42.6%48.0%44.4%23.8%38.5%82.6%0.0%0.0%0.0%16.4%79.7%39.8%

Returns use average equity or assets over the year. Return on equity is left blank when equity is negative or so small that the ratio says nothing (above ±200%); interest cover is left blank above 200 times. Price-based ratios such as P/E are on the valuation page.

Financial health

3 of 6 checks passed · September 27, 2026
What it owns · $6.8bn
Short-term assets $3.0bnLonger-term assets $3.8bn
What it owes, and who funded it · $4.3bn
Short-term liabilities $1.2bnShareholders' equity $3.1bn
  • Short-term assets cover short-term liabilities $3.0bn of assets due within a year against $1.2bn of liabilities due within a year.
  • Short-term assets cover long-term liabilities Not assessable from the reported split. Not assessable.
  • More cash than debt $1.3bn of cash against $1.8bn of debt.
  • Debt below 40% of shareholders' equity Debt is 57% of equity.
  • Debt burden no higher than five years ago Debt to equity moved from 9% to 57% over five years.
  • A year's operating cash flow covers at least 20% of debt $1.2bn of operating cash flow against $1.8bn of debt.
  • Operating profit covers interest at least five times over Operating income of $960m against $98m of interest.

From Illumina, Inc.'s latest balance sheet as filed. Checks are fixed, documented rules (methodology), counted only where the company reports the figures — a dot means the filing doesn't break the item out. Descriptions of reported data, not advice.

Moat

70 /100

Strong moat

How hard Illumina's competitive advantage looks for rivals to wear away, judged from 10 years of its own filings: returns on capital, pricing power, profit durability, cash conversion and discipline.

  • Returns on capital 20 / 20

    Cash operating profit has been a median 19.4% of total assets over 10 years.

  • Pricing power 20 / 20

    Gross margin has been a median 67.1%, moving by 2.5 percentage points (standard deviation) across 10 years.

  • Durability 6 / 20

    Operating margin has been a median 19.1%; its worst year was -85.4%.

  • Cash conversion 20 / 20

    Free cash flow was positive in 10 of 10 years, at a median 20.2% of revenue.

  • Discipline 10 / 20

    The diluted share count rose 3.4% over five years; stock-based pay has been a median 6.4% of revenue.

AI disruption exposure: Medium. In this industry, AI could change how the product is made or sold, without replacing the core asset. The score above includes a 5-point deduction for that exposure (75 before it).

A rules-based reading of reported figures, not a forecast and not investment advice. How the score is built: methodology.

Compare with peers

Head to head: ILMN vs WATILMN vs MTDCRL vs ILMN

More: Life Sciences Tools & Services stocks compared, Health Care sector, rankings of US companies

Figures from Illumina, Inc.'s SEC filings (10-K and 10-Q), retrieved October 30, 2026. How we read and check them: methodology and data sources. Not investment advice. Back to Illumina, Inc.