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Leonabio, Inc. (LONA) stock

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NASDAQ: LONA Nasdaq Biotechnology Next results ~November 5, 2026

Leonabio, Inc. is a US-listed company in the biotechnology industry. Its financial year ends in December.

Who’s trading

What company insiders, investment funds and members of Congress have been doing with the stock, from their own filings.

  • Insiders1 buying, 5 selling1 purchase and 10 sales by directors and officers, last 12 monthsInsider trades
  • Funds14 adding, 10 cuttingOf 5 active managers that changed their stake, 5 added; quarter to June 30, 2026Fund buyers and sellers

The Fundamentalytics view

Next results ~November 5, 2026 (estimated)

Current signal Results well ahead of expectations: Reported earnings per share beat the analysts' consensus estimate by 41% in the quarter to 2026-06-30, the 2nd beat in the last four quarters.

Assembled from SEC-filed figures — the full workings are on this page and in our methodology. Observations, not recommendations.

Strengths

Nothing in Leonabio, Inc.'s latest figures clears our strength thresholds.

Things to watch

  • Results due soon. Results are expected around 5 November; the share price can move sharply on the day.
  • Volatile shares. Over the past year the shares showed annualised volatility of 120% and a beta of 1.0 against the S&P 500.
  • Missing expectations. Earnings per share fell short of the consensus estimate in 2 of the last four quarters.

Latest results

Earnings per share
-$0.80 against an average estimate of -$1.36: beat by 41.0%
Share reaction
-2.0% in the first session after the results on August 14, 2026, against -0.7% for the S&P 500
Next report
August 6, 2026

Leonabio's figures from its SEC filings and results release; estimates are the analysts' average. Not a recommendation.

Price chart

  • 1 day-4.3%
  • 1 week-0.6%
  • 1 month-1.9%
  • This year-37.5%
  • 1 year+13.8%
  • 5 years-96.9%
  • S&P 500 this year+11.2%

Closing prices to 2026-11-02. Price change only, dividends excluded.

Loading chart…

Third-party market data · may be delayed

At a glance

Trailing twelve months, from SEC filings

Earnings

Last results
August 14, 2026
Next results (est.)
November 5, 2026

News & updates

Updated October 31, 2026

Company announcements, filed results and changes that matter to shareholders.

  1. Insider trade
  2. Announcement
  3. Announcement
  4. Results

Refreshed hourly when new source data is available. Summaries are checked against company releases and SEC filings. Company announcement headlines are labelled when a checked summary is unavailable.

No model value for Leonabio, Inc. at the moment. Current status: limited reported history: available models are shown without a Buy/Hold/Sell rating. Available reported financials are shown below.

Fundamentalytics rating

model v1.6 · 2026-11-03

Not rated: limited reported history: available models are shown without a Buy/Hold/Sell rating.

Valuation models

We value Leonabio, Inc. as an operating company, with every model that fits that kind of business. Cost of equity 11.2%: the 10-year Treasury yield (4.9%) plus a beta of 1.4 times a 4.5% equity risk premium.

Value per share by model
Model Value per share In the combined value?
Price-to-earnings vs peers Earnings per share times peers' typical (harmonic-mean) price-to-earnings. — Does not apply: no twelve-month earnings or share count in the filings yet
Residual income Book value plus the present value of returns above the cost of equity, fading over ten years. — Does not apply: no twelve-month earnings or share count in the filings yet
Justified price-to-book Book value times (return on equity - growth) / (cost of equity - growth): steady-state returns. — Does not apply: no twelve-month earnings or share count in the filings yet
Revenue-to-maturity model Revenue grown to maturity with the cash margin moving to the industry's; for companies not yet profitable. — Does not apply: revenue and margins don't support a positive value
Price-to-sales vs peers Sales per share times peers' typical price-to-sales; used only when earnings are negative. — Does not apply: no twelve-month earnings or share count in the filings yet
Combined value Weighted average of the models that apply: the primary model (price-to-earnings vs peers) counts double. Models more than 5x or less than 0.2x the share price, or more than 3x away from the other models' median, are left out. — No model applies: the filings don’t yet support a value.

Different models fail in different ways, so where several apply we average them rather than trust one. Peer-based models compare Leonabio, Inc. with Biotechnology in our coverage, using third-party market data. Model values are estimates under stated assumptions, updated as new filings arrive; not price targets or investment advice. How each model works.

Moat

Not assessed: fewer than five years of comparable figures in the filings. AI disruption exposure for this industry: Medium.

A rules-based reading of reported figures, not a forecast and not investment advice. How the score is built: methodology.

Forecasts and guidance

Analysts' consensus

Leonabio, Inc.: consensus estimates
Fiscal yearEPSGrowthRevenueGrowth
Current −$2.83 +89% — 0%
Next −$2.34 +18% — 0%

How the EPS forecast has moved

The consensus EPS forecast for the current fiscal year is −9.1% on 90 days ago. In the last 30 days, 2 analysts raised Leonabio, Inc.'s forecast and 1 cut it.

Consensus EPS forecast Leonabio, Inc., last 90 days
−$4.00 −$3.00 −$2.00 −$1.00 $0.00 90 days ago 60 days ago 30 days ago 7 days ago Now Current fiscal year, 90 days ago: −$3.12 Current fiscal year, 60 days ago: −$2.83 Current fiscal year, 30 days ago: −$2.83 Current fiscal year, 7 days ago: −$2.83 Current fiscal year, Now: −$2.83 −$2.83 Next fiscal year, 90 days ago: −$1.79 Next fiscal year, 60 days ago: −$2.34 Next fiscal year, 30 days ago: −$2.34 Next fiscal year, 7 days ago: −$2.34 Next fiscal year, Now: −$2.34 −$2.34

Average of analysts' published estimates (third-party data).

View chart data
Period Current fiscal yearNext fiscal year
90 days ago −$3.12−$1.79
60 days ago −$2.83−$2.34
30 days ago −$2.83−$2.34
7 days ago −$2.83−$2.34
Now −$2.83−$2.34

Earnings against estimates

Leonabio, Inc.: reported EPS against the consensus estimate
Quarter toEstimateActualSurprise
Jun 2026 −$1.36 −$0.80 +41.0%
Mar 2026 −$2.50 −$1.73 +30.8%
Dec 2025 −$1.27 −$18.92 −1393.7%
Sept 2025 −$1.22 −$1.68 −37.7%

Adjusted EPS as companies report it, against the average analyst estimate.

Analyst recommendations

4 analysts, Oct 2026
Buy4100%
Hold00%
Sell00%

Monthly trend

  1. Oct 2026224
  2. Sep 2026224
  3. Aug 2026224
  4. Jul 2026224

Counts of recommendations published by analysts covering Leonabio, Inc., by month. Source: Aggregated broker recommendations (third-party data). Aggregated counts only: we do not reproduce any firm's recommendation or price target, and these are not Fundamentalytics ratings.

Positioning

Short interest
1.2%
of tradable shares
Days to cover
0.2
at average volume
Short interest, 1 month
+269%
to October 15, 2026
Held by institutions
96%
of shares
Held by insiders
37.5%
of shares
Employees
19
full time

Consensus figures average analysts' published estimates (third-party data); guidance is the company's own. Neither is our forecast. Short interest is reported twice a month and lags. Market data may be delayed.

This section is general information, not investment advice or a personal recommendation, and it does not take account of your objectives or circumstances. Forecasts and guidance are estimates, not promises: companies miss their own guidance and analysts' figures are often revised. Prices can fall as well as rise, and you can lose money. See our disclaimer.

Share-price performance

Market data may be delayed

Return and risk by year

Leonabio, Inc.: yearly return, monthly win rate and worst fall against the S&P 500
Calendar year 202120222023202420252026 to date
Return
LONA−62%−76%−23%−76%+29%−38%
Industry peers (median)−35%−56%−17%−28%−5%−26%
S&P 500+29%−18%+26%+25%+18%+11%
Months that ended higher
LONA50%33%33%50%58%46%
S&P 50075%42%67%75%75%46%
Largest fall from a high during the year
LONA−73%−80%−67%−90%−62%−75%
S&P 500−5%−25%−10%−8%−19%−9%

Worst fall since September 18, 2020: 99% from December 23, 2020 to April 16, 2025. Getting back needed a 14878% gain, and the shares have not yet recovered.

Price behaviour

52-week range
$2.87 – $11.68
From 52-week high
−59.5%
vs 50-day average
−21.1%
vs 200-day average
−37.0%
Volatility (1 year)
120%
Beta vs S&P 500
0.96

Volatility is the annualised standard deviation of daily returns. Beta 1.5 means the shares typically moved 1.5% for each 1% move in the S&P 500 over the past year. Prices to November 2, 2026.

Share price after results

Next day
6 up, 6 down
typical move ±5.4%
After a week
9 up, 3 down
typical move ±10.3%
After a month
4 up, 8 down
typical move ±13.5%
Leonabio, Inc.: share-price change after each results release
Results releasedNext dayS&P 500 next day5 days21 days
August 14, 2026 −2.0% −0.7% −2.4% −8.0%
May 7, 2026 +6.6% +0.5% +16.8% −8.8%
March 26, 2026 −0.7% −3.5% +25.7% −7.5%
November 6, 2025 −8.1% −1.0% +12.1% −7.4%
August 7, 2025 +3.4% +0.7% +5.0% +1.6%
May 9, 2025 +1.1% +3.2% +1.9% +29.2%
February 27, 2025 −6.4% −0.1% −20.3% −30.5%
November 7, 2024 −5.7% +1.2% +2.0% −11.0%
August 1, 2024 +0.6% −3.3% −3.8% −3.1%
May 15, 2024 +23.2% +1.0% +19.1% +15.5%
February 22, 2024 +6.2% +2.1% +4.1% −31.1%
January 8, 2024 −0.2% +1.3% +10.1% +8.0%

From the close before the release date to the close 1, 5 and 21 trading days after it, so releases before the open and after the close are both captured. Past moves don't predict future ones.

Fundamentals

Data: SEC EDGAR XBRL company facts (as filed in 10-K/10-Q); forms . Generated November 3, 2026. Definitions in our methodology.

Reported value
$70.4M
Institutions reporting
44
Shares held vs prior quarter
▲ 11.9%
Positions opened / closed
6 / 3

Top buyers and sellers, Q2 2026: 14 institutions bought and 10 sold ; the biggest buyer was Adage Capital Partners Gp, L.L.C (+300K shares) and the biggest seller Seven Fleet Capital Management LP (−11K). See which funds bought and sold →

Largest reported holders, June 30, 2026
Manager Value Shares Share of 13F value Shares QoQ
Perceptive Advisors LLC $17.1M 1.9M 24.3% 0.0%
Kalehua Capital Management LLC $7.2M 787K 10.3% 0.0%
ADAR1 Capital Management, LLC $7.1M 777K 10.1% ▲ 6.8%
Acorn Capital Advisors, LLC $5.8M 635K 8.3% 0.0%
Nea Management Company, LLC $4.3M 464K 6.1% 0.0%
Commodore Capital LP $4.3M 464K 6.1% 0.0%
Tcg Crossover Management, LLC $4.3M 464K 6.1% 0.0%
Spruce Street Capital LP $3.6M 394K 5.1% 0.0%
Blackstone Inc. $3M 325K 4.2% —
Adage Capital Partners Gp, L.L.C. $2.8M 300K 3.9% New
Vanguard Capital Management LLC $2.5M 275K 3.6% ▲ 41.3%
Seven Fleet Capital Management LP $1.4M 154K 2.0% ▼ 6.4%

From Form 13F filings with the SEC ( quarterly data sets), as reported by each manager for June 30, 2026 and filed up to 45 days later. 13F reports cover long US-listed positions of managers above $100M only, so this is not Leonabio, Inc.'s complete shareholder register. Values are as reported by the filers .

Insider trading activity

Full insider history and chart
Recent insider open-market transactions
Insider Date Trade Shares Price Value
Portman David J. 10% owner October 26, 2026 Buy 3,149,470 $3149.47 $9.9B
San Martin Javier CHIEF MEDICAL OFFICER March 4, 2026 Sell 1,720 $5.37 $9,236
Church Kevin CHIEF SCIENTIFIC OFFICER March 4, 2026 Sell 1,359 $5.37 $7,298
Worthington Mark GENERAL COUNSEL and CCO March 4, 2026 Sell 1,328 $5.37 $7,131
Renninger Robert CHIEF FINANCIAL OFFICER March 4, 2026 Sell 906 $5.37 $4,865
Litton Mark James PRESIDENT and CEO March 4, 2026 Sell 5,156 $5.37 $27,688
Worthington Mark General Counsel and CCO January 2, 2026 Sell 876 $6.88 $6,027
Church Kevin CHIEF SCIENTIFIC OFFICER January 2, 2026 Sell 876 $6.88 $6,027
Renninger Robert Chief Financial Officer January 2, 2026 Sell 297 $6.88 $2,043
Litton Mark James President and CEO January 2, 2026 Sell 2,586 $6.88 $17,792
San Martin Javier CHIEF MEDICAL OFFICER January 2, 2026 Sell 1,644 $6.88 $11,311

From insiders' Form 4 filings with the SEC. Excludes awards, option exercises and shares withheld for tax. "Pre-set plan" means the filing marks the trade as made under a Rule 10b5-1 plan. See every insider trade since five years ago, on a price chart.

Earnings dates and SEC filings

Results announcements

Next expected around November 5, 2026 estimated from the company's past filing pattern, not announced

  • August 14, 2026
  • May 7, 2026
  • March 26, 2026
  • November 6, 2025
  • August 7, 2025
  • May 9, 2025

Recent SEC filings

Data status

When each part of this page on Leonabio, Inc. was last updated.

DataLast updatedSource
Share priceExchange closing prices
News and updatesCompany releases and SEC 8-K filings
Analyst estimatesAggregated analyst estimates
Valuation and scoresOur models, from the filed figures

How we build and check these figures: methodology and data sources.

Leonabio, Inc. in brief

What does Leonabio, Inc. do?
Leonabio, Inc. is a US-listed company in the biotechnology industry. Its financial year ends in December.
What is Leonabio, Inc.'s stock ticker?
Leonabio, Inc. trades under the ticker LONA on Nasdaq. This page brings together its financial statements, valuation models, ownership and recent company updates.
Who are Leonabio, Inc.'s largest institutional shareholders?
By value reported in 13F filings for June 30, 2026, the largest reported holders are Perceptive Advisors LLC, Kalehua Capital Management LLC and ADAR1 Capital Management, LLC. 13F reports cover long US-listed positions of managers above $100M, filed up to 45 days after quarter end.
Are insiders buying or selling Leonabio, Inc. stock?
Over the last 12 months, Leonabio, Inc.'s directors and officers reported 1 open-market purchases and 10 sales on Form 4. The insider trading page charts every trade.
When is Leonabio, Inc.'s next earnings date?
Around November 5, 2026, estimated from the spacing of its past results announcements (8-K filings). That is an estimate, not a confirmed date — Leonabio, Inc. announces its own schedule.