Serina Therapeutics, Inc. is a US-listed company in the biotechnology industry. Its financial year ends in December.
Loading chart…
Third-party market data · may be delayed
Under review: every model's value for Serina Therapeutics, Inc. is far from the share price, which usually points to a data problem (a merger, a share-count change, a one-off) rather than a bargain or a bubble.
Under review: data-quality checks not passed. We'll show the comparison once resolved.
Serina Therapeutics, Inc. valuation: adjust assumptions and compare models →
What company insiders, investment funds and members of Congress have been doing with the stock, from their own filings.
Serina Therapeutics has little or no product revenue yet; it used $21m of cash in the twelve months to June 2026. The diluted share count is up 36.4% on a year earlier, which dilutes existing holders. It passes 2 of our 2 financial-health checks.
Our model value for Serina Therapeutics is under review, so past values are not shown until it is resolved.
Source: 10-Q filed August 13, 2026 on SEC EDGAR · Financials · Valuation
Written from the company's filings and our models when each quarter's report arrives. Figures in older notes are as published at the time. Not investment advice.
Serina Therapeutics, Inc.'s trailing-twelve-month revenue grew 132.1% year on year, with a free-cash-flow margin of -13856.9%.
Current signal Revenue growth accelerating: TTM revenue growth rose to 132.1% (+228.5pp vs the prior quarter).
Assembled from SEC-filed figures — the full workings are on this page and in our methodology. Observations, not recommendations.
Loading chart…
Third-party market data · may be delayed
Company announcements, filed results and changes that matter to shareholders.
| At fiscal year end | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|
| Share price | $106.79 | $65.00 | $54.29 | $38.93 | $19.71 | $13.75 | $5.01 | $1.91 |
| Market value | $730m | $474m | $400m | $289m | $4165 | $101m | $37m | $19m |
| + Net debt (− = net cash) | −$7m | −$2m | −$527000 | $14m | $21m | −$5m | −$4m | −$110000 |
| Enterprise value | $723m | $472m | $400m | $303m | $21m | $96m | $33m | $19m |
| Multiples | ||||||||
| Price / sales | n/m | n/m | n/m | n/m | 0.1x | 32.1x | n/m | 149.9x |
| Price / earnings | — | — | — | — | — | 19.2x | — | — |
| Price / free cash flow | — | — | — | — | — | — | — | — |
| EV / EBITDA | — | — | — | — | — | — | — | — |
Weak moat
How hard Serina Therapeutics's competitive advantage looks for rivals to wear away, judged from 8 years of its own filings: returns on capital, pricing power, profit durability, cash conversion and discipline.
Net income has been a median -126.8% of total assets over 8 years.
Gross margin has been a median 79.9%, moving by 30.4 percentage points (standard deviation) across 6 years.
Operating margin has been a median -4153.4%; its worst year was -30442.9%.
AI disruption exposure: Medium. In this industry, AI could change how the product is made or sold, without replacing the core asset. The score above includes a 5-point deduction for that exposure (37 before it).
| Fiscal year | EPS | Growth | Revenue | Growth |
|---|---|---|---|---|
| Current | −$1.58 | +17% | — | −100% |
| Next | −$1.16 | +27% | — | 0% |
The consensus EPS forecast for the current fiscal year is −19.0% on 90 days ago. In the last 30 days, 2 analysts raised Serina Therapeutics, Inc.'s forecast and 0 cut it.
Average of analysts' published estimates (third-party data).
| Period | Current fiscal year | Next fiscal year |
|---|---|---|
| 90 days ago | −$1.95 | −$1.57 |
| 60 days ago | −$1.58 | −$1.16 |
| 30 days ago | −$1.58 | −$1.16 |
| 7 days ago | −$1.58 | −$1.16 |
| Now | −$1.58 | −$1.16 |
| Quarter to | Estimate | Actual | Surprise |
|---|---|---|---|
| Jun 2026 | −$0.35 | −$0.52 | −49.7% |
| Mar 2026 | −$0.44 | −$0.53 | −19.8% |
| Dec 2025 | −$0.50 | −$0.31 | +38.0% |
| Sept 2025 | −$0.53 | −$0.51 | +3.1% |
Adjusted EPS as companies report it, against the average analyst estimate.
Last 12 months −63.0%
| Part | Then | Now | Effect |
|---|---|---|---|
| Revenue (last 12 months) | $130000 | $130000 | 0.0% |
| P/S multiple | n/m | 175.9x | −49.5% |
| Share count | 9m | 12m | −26.7% |
Biggest factor: p/s multiple. Loss-making at one end, so the split uses price/sales.
| Calendar year | 2021 | 2022 | 2023 | 2024 | 2025 | 2026 to date |
|---|---|---|---|---|---|---|
| Return | ||||||
| SER | −28% | −49% | −30% | −64% | −62% | −3% |
| Industry peers (median) | −36% | −57% | −17% | −28% | −5% | −27% |
| S&P 500 | +29% | −18% | +26% | +25% | +18% | +11% |
| Months that ended higher | ||||||
| SER | 33% | 33% | 42% | 33% | 42% | 55% |
| S&P 500 | 75% | 42% | 67% | 75% | 75% | 46% |
| Largest fall from a high during the year | ||||||
| SER | −80% | −55% | −63% | −81% | −70% | −64% |
| S&P 500 | −5% | −25% | −10% | −8% | −19% | −9% |
Worst fall since November 29, 2018: 99% from December 3, 2018 to March 18, 2026. Getting back needed a 15246% gain, and the shares have not yet recovered.
| Results released | Next day | S&P 500 next day | 5 days | 21 days |
|---|---|---|---|---|
| August 13, 2026 | −0.7% | +0.5% | −6.0% | −13.1% |
| May 14, 2026 | +5.1% | −0.4% | +21.0% | +22.4% |
| March 25, 2026 | +7.4% | −1.2% | −12.8% | −18.9% |
| November 13, 2025 | +1.7% | −1.7% | −6.5% | −25.6% |
| August 11, 2025 | −0.9% | +0.9% | −5.2% | −8.9% |
| May 8, 2025 | −2.1% | +0.6% | −1.9% | +6.4% |
| March 24, 2025 | −3.7% | +2.0% | +18.1% | +20.4% |
| January 6, 2025 | −7.5% | −0.6% | −5.4% | −11.1% |
| November 12, 2024 | −5.1% | −0.3% | −5.1% | −10.8% |
| August 9, 2024 | −14.8% | +0.5% | −5.2% | −9.0% |
| May 14, 2024 | +6.3% | +1.7% | +18.9% | +16.1% |
| March 22, 2024 | −5.2% | −0.5% | −11.0% | −24.8% |
Source: SEC EDGAR filings. Retrieved November 1, 2026.
| Period | Revenue (TTM) |
|---|---|
| FY23 Q1 | $59K |
| FY23 Q2 | $54K |
| FY23 Q3 | $74K |
| FY23 Q4 | $3.2M |
| FY24 Q1 | $3.1M |
| FY24 Q2 | $3.2M |
| FY24 Q3 | $3.2M |
| FY24 Q4 | $56K |
| FY25 Q1 | $51K |
| FY25 Q2 | $130K |
| FY25 Q3 | $116K |
| FY25 Q4 | $130K |
Source: SEC EDGAR filings. Retrieved November 1, 2026.
| Period | Revenue growth, TTM YoY |
|---|---|
| FY23 Q1 | -36.6% |
| FY23 Q2 | -20.6% |
| FY23 Q3 | 39.6% |
| FY23 Q4 | 9173.5% |
| FY24 Q1 | 5201.7% |
| FY24 Q2 | 5774.1% |
| FY24 Q3 | 4166.2% |
| FY24 Q4 | -98.2% |
| FY25 Q1 | -98.4% |
| FY25 Q2 | -95.9% |
| FY25 Q3 | -96.3% |
| FY25 Q4 | 132.1% |
Source: SEC EDGAR filings. Retrieved November 1, 2026.
| Period | Operating margin (TTM) |
|---|---|
| FY23 Q1 | -9974.6% |
| FY23 Q2 | -9701.9% |
| FY23 Q3 | -6962.2% |
| FY23 Q4 | -99.2% |
| FY24 Q1 | -143.5% |
| FY24 Q2 | -233.6% |
| FY24 Q3 | -356.6% |
| FY24 Q4 | -30442.9% |
| FY25 Q1 | -40362.7% |
| FY25 Q2 | -17141.5% |
| FY25 Q3 | -20141.4% |
| FY25 Q4 | -18478.5% |
Source: SEC EDGAR filings. Retrieved November 1, 2026.
| Period | FCF margin (TTM) |
|---|---|
| FY19 Q4 | -625.1% |
| FY20 Q1 | -717.1% |
| FY20 Q2 | -880.3% |
| FY20 Q3 | -1186.6% |
| FY20 Q4 | -2170.9% |
| FY24 Q2 | -337.1% |
| FY24 Q3 | -396.4% |
| FY24 Q4 | -30641.1% |
| FY25 Q1 | -39000.0% |
| FY25 Q2 | -12059.2% |
| FY25 Q3 | -14288.8% |
| FY25 Q4 | -13856.9% |
| Fiscal year | 2017 Dec 2017 | 2018 Dec 2018 | 2019 Dec 2019 | 2020 Dec 2020 | 2021 Dec 2021 | 2022 Dec 2022 | 2023 Dec 2023 | 2024 Dec 2024 | 2025 Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|
| Income | |||||||||
| Revenue | 1 | 1 | 2 | 0 | 0 | 0 | 3 | 0 | 0 |
| Gross profit | 1 | 1 | 1 | 0 | 0 | 0 | 0 | — | — |
| EBITDA | −6 | −11 | −12 | −9 | — | — | −3 | −17 | −24 |
| Operating income | −7 | −11 | −13 | −10 | −8 | −7 | −3 | −17 | −24 |
| Net income | −7 | −8 | −12 | −11 | −9 | −10 | 5 | −11 | −19 |
| Diluted EPS | −$1.07 | −$1.07 | −$1.69 | −$1.48 | −$1.17 | −$49.54 | $0.73 | −$1.51 | −$1.91 |
| Growth (year on year) | |||||||||
| Revenue | — | −0.6% | +23.8% | −79.1% | −60.1% | −76.4% | +>999% | −98.2% | +132.1% |
| Net income | — | — | — | — | — | — | — | −311.4% | — |
| Diluted EPS | — | — | — | — | — | — | — | −306.8% | — |
| Margins | |||||||||
| Gross margin | 88.0% | 73.9% | 85.9% | 92.8% | 86.8% | 61.8% | 3.2% | — | — |
| EBITDA margin | −462.8% | −801.4% | −704.1% | <−999% | — | — | −96.4% | <−999% | <−999% |
| Operating margin | −474.6% | −805.5% | −726.8% | <−999% | <−999% | <−999% | −99.2% | <−999% | <−999% |
| Net margin | −468.7% | −537.4% | −703.4% | <−999% | <−999% | <−999% | 167.1% | <−999% | <−999% |
| Free-cash-flow margin | −447.7% | −574.2% | −625.1% | <−999% | — | — | −94.5% | <−999% | <−999% |
| Cash flow | |||||||||
| Cash from operations | −6 | −8 | −10 | −8 | −8 | −6 | −2 | −17 | −18 |
| Capital spending | 0 | 0 | 1 | 0 | — | — | 1 | 0 | 0 |
| Free cash flow | −6 | −8 | −11 | −8 | — | — | −3 | −17 | −18 |
| Stock-based pay | 0 | 1 | 2 | 1 | 1 | 1 | 0 | 3 | 4 |
| Free cash flow after stock pay | −6 | −9 | −13 | −9 | — | — | −3 | −20 | −22 |
| Balance sheet | |||||||||
| Cash | 7 | 7 | 2 | 1 | 1 | 1 | 8 | 4 | 3 |
| Total debt | 0 | 0 | 0 | 0 | 15 | 21 | 3 | 0 | 3 |
| Net debt (negative = net cash) | −7 | −7 | −2 | −1 | 14 | 21 | −5 | −4 | −0 |
| Diluted shares | 6m | 7m | 7m | 7m | 7m | — | 7m | 7m | 10m |
| Quarter | 2024 Q2 Jun 2024 | 2024 Q3 Sept 2024 | 2024 Q4 Dec 2024 | 2025 Q1 Mar 2025 | 2025 Q2 Jun 2025 | 2025 Q3 Sept 2025 | 2025 Q4 Dec 2025 | 2026 Q2 Jun 2026 |
|---|---|---|---|---|---|---|---|---|
| Income | ||||||||
| Revenue | 51 | 14 | −14 | 0 | 130 | 0 | 0 | 0 |
| EBITDA | −3,866 | −5,312 | −5,587 | −5,858 | −5,565 | −6,392 | −6,156 | −6,748 |
| Operating income | −3,866 | −5,312 | −5,549 | −5,858 | −5,565 | −6,392 | −6,207 | −6,784 |
| Net income | 5,204 | 1,410 | −2,740 | −4,813 | −6,448 | −4,585 | −3,336 | −6,356 |
| Diluted EPS | $0.51 | $0.13 | −$0.27 | −$0.49 | −$0.66 | −$0.45 | −$0.31 | −$0.55 |
| Growth (year on year) | ||||||||
| Revenue | +628.6% | −51.7% | −100.5% | −100.0% | +154.9% | −100.0% | — | −100.0% |
| EBITDA | — | — | <−999% | — | — | — | — | — |
| Operating income | — | — | <−999% | — | — | — | — | — |
| Net income | +544.1% | −19.5% | −360.7% | — | −223.9% | −425.2% | — | — |
| Diluted EPS | +363.6% | −43.5% | −268.8% | — | −229.4% | −446.2% | — | — |
| Margins | ||||||||
| EBITDA margin | <−999% | <−999% | >999% | — | <−999% | — | — | — |
| Operating margin | <−999% | <−999% | >999% | — | <−999% | — | — | — |
| Net margin | >999% | >999% | >999% | — | <−999% | — | — | — |
| Free-cash-flow margin | <−999% | <−999% | >999% | — | <−999% | — | — | — |
| Cash flow | ||||||||
| Cash from operations | −8,009 | −2,962 | −4,589 | −4,322 | −3,750 | −3,850 | −6,033 | −6,684 |
| Capital spending | 0 | 3 | 5 | 0 | 46 | 13 | 0 | 28 |
| Free cash flow | −8,009 | −2,965 | −4,594 | −4,322 | −3,796 | −3,863 | −6,033 | −6,712 |
| Stock-based pay | 458 | 1,096 | 988 | 956 | 890 | 999 | 948 | 1,051 |
| Free cash flow after stock pay | −8,467 | −4,061 | −5,582 | −5,278 | −4,686 | −4,862 | −6,981 | −7,763 |
| Last 12 months unless stated | SER | CLDX | IBIO | LSTA | AIM | CLNN | Median |
|---|---|---|---|---|---|---|---|
| Revenue, last 12 months | $130000 | $158000 | $100000 | $100000 | $95000 | $197000 | $55m |
| Revenue growth, last 12 months | 132.1% | −97.3% | −75.0% | −90.7% | −21.5% | −31.1% | 12.7% |
| Revenue growth, 3-year average | 56.4% | −63.5% | −62.4% | — | −17.3% | −36.9% | 14.3% |
| Revenue growth, latest quarter | −100.0% | −97.0% | −100.0% | −100.0% | 4.0% | 233.3% | 10.2% |
| Gross margin | 3.2% | — | 59.9% | 7.7% | −968.5% | 70.1% | 82.8% |
| Operating margin | <−999% | <−999% | <−999% | <−999% | <−999% | <−999% | −191.1% |
| Operating margin, 3-year average | <−999% | <−999% | <−999% | <−999% | <−999% | <−999% | −365.3% |
| Net margin | <−999% | <−999% | <−999% | <−999% | <−999% | <−999% | −172.8% |
| Cash from operations / revenue | <−999% | <−999% | <−999% | <−999% | <−999% | <−999% | −168.8% |
| Free-cash-flow margin | <−999% | <−999% | <−999% | <−999% | <−999% | <−999% | −168.1% |
| Free-cash-flow margin, 3-year average | <−999% | <−999% | <−999% | <−999% | <−999% | <−999% | −313.4% |
| Stock pay / revenue | >999% | >999% | >999% | >999% | 0.0% | >999% | 20.7% |
| Change in share count | 36.4% | 4.7% | 13.9% | 5.1% | 49.8% | 35.4% | 8.3% |
| Manager | Value | Shares | Share of 13F value | Shares QoQ |
|---|---|---|---|---|
| Sio Capital Management, LLC | $1.9M | 1.0M | 71.1% | 0.0% |
| Vanguard Capital Management LLC | $314,664 | 162K | 11.5% | ▲ 1.9% |
| Waverly Advisors, LLC | $130,934 | 67K | 4.8% | 0.0% |
| Geode Capital Management, LLC | $98,955 | 51K | 3.6% | ▼ 21.5% |
| Keel Point, LLC | $41,726 | 22K | 1.5% | 0.0% |
| Northern Trust Corp | $40,296 | 21K | 1.5% | New |
| Vanguard Fiduciary Trust Co | $38,817 | 20K | 1.4% | 0.0% |
| Avidian Wealth Enterprises, LLC | $36,472 | 19K | 1.3% | 0.0% |
| Jane Street Group, LLC | $29,962 | 15K | 1.1% | ▼ 61.1% |
| State Street Corp | $24,751 | 13K | 0.9% | 0.0% |
| Caitong International Asset Management Co., Ltd | $7,263 | 4K | 0.3% | ▼ 6.0% |
| Wells Fargo & Company | $7,006 | 4K | 0.3% | ▲ 0.1% |
From Form 13F filings with the SEC ( quarterly data sets), as reported by each manager for June 30, 2026 and filed up to 45 days later. 13F reports cover long US-listed positions of managers above $100M only, so this is not Serina Therapeutics, Inc.'s complete shareholder register. Values are as reported by the filers .
| Insider | Date | Trade | Shares | Price | Value |
|---|---|---|---|---|---|
| Brannan Stephen K. Director | July 7, 2026 | Buy | 1,000 | $2.03 | $2,030 |
| Wilson Karen J Director | June 12, 2026 | Buy | 5,000 | $1.77 | $8,850 |
| Wilson Karen J Director | June 11, 2026 | Buy | 5,100 | $1.75 | $8,925 |
| Wilson Karen J Director | May 22, 2026 | Buy | 10,000 | $1.93 | $19,300 |
| Venkatesan Jay Director | May 22, 2026 | Buy | 589 | $1.78 | $1,048 |
| Wilson Karen J Director | May 21, 2026 | Buy | 10,000 | $1.77 | $17,700 |
| Marshall Richard Peter Director | May 19, 2026 | Buy | 12,183 | $1.65 | $20,102 |
| Moreadith Randall Chief Scientific Officer | March 23, 2026 | Sell pre-set plan | 6,500 | $2.86 | $18,590 |
| Moreadith Randall Chief Scientific Officer | March 19, 2026 | Sell pre-set plan | 39,000 | $2.50 | $97,500 |
| Moreadith Randall Chief Scientific Officer | February 2, 2026 | Sell pre-set plan | 6,500 | $3.03 | $19,695 |
| Moreadith Randall Chief Scientific Officer | January 28, 2026 | Sell pre-set plan | 6,500 | $3.57 | $23,205 |
| Moreadith Randall Chief Scientific Officer | January 22, 2026 | Sell pre-set plan | 2,500 | $2.95 | $7,375 |
From insiders' Form 4 filings with the SEC. Excludes awards, option exercises and shares withheld for tax. "Pre-set plan" means the filing marks the trade as made under a Rule 10b5-1 plan. See every insider trade since five years ago, on a price chart.
Next expected around November 12, 2026 estimated from the company's past filing pattern, not announced
| Data | Last updated | Source |
|---|---|---|
| Share price | Exchange closing prices | |
| Financial statements | SEC 10-K and 10-Q filings | |
| News and updates | Company releases and SEC 8-K filings | |
| Analyst estimates | Aggregated analyst estimates | |
| Valuation and scores | Our models, from the filed figures |
New research on the companies we cover arrives in the weekly email. Free, one email a week.
