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Spero Therapeutics, Inc. income statement

In fiscal 2025, Spero Therapeutics, Inc. reported revenue of $66.8m, up 39.2% on the year before, operating income of $6.3m (a 9.5% margin) and net income of $8.6m, or $0.15 per diluted share. Every line below comes from the company's 10-K and 10-Q filings; column headings link to the filing.

Income statement

US$ millions unless shown otherwise. Fiscal years, plus the last twelve months (LTM) when newer.

Spero Therapeutics, Inc.: income statement, annual
Fiscal year2016Dec 20162017Dec 20172018Dec 20182019Dec 20192020Dec 20202021Dec 20212022Dec 20222023Dec 20232024Dec 20242025Dec 2025LTMJun 2026
Revenue0241891854104486747
Research and development2633346667654851973821
General and administrative711131621423626242120
Operating income−33−42−43−63−79−88−4221−7366
Income before tax−33−40−42−61−78−90−4625−699—
Income tax0000000300—
Net income−25−39−42−61−78−904623−6997
Diluted EPS−$11.98−$17.82−$2.60−$3.35−$3.52−$2.91−$1.23$0.43−$1.27$0.15$0.12
Diluted shares (average)2m3m16m18m22m31m38m53m54m59m60m
EBITDA−33−41−42−62−78−87−4122−736—

EBITDA is operating income plus depreciation and amortisation. EPS and share counts are restated for stock splits. A dash means the company did not report the line for that period; expense lines are shown as reported, so they need not add up to the totals when a company reports other items between them.

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Figures from Spero Therapeutics, Inc.'s SEC filings (10-K and 10-Q), retrieved October 29, 2026. How we read and check them: methodology and data sources. Not investment advice. Back to Spero Therapeutics, Inc.