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Cue Biopharma vs Zymeworks

Zymeworks is the larger business, with $106m of revenue in fiscal 2025 against $27.5m for Cue Biopharma (3.9 times as much). Cue Biopharma grew faster (195.7% against 38.9%). Zymeworks kept more of each dollar of sales as profit: a net margin of -76.6% against -96.9%.

Latest fiscal yearCue BiopharmaCUE, 2025ZymeworksZYME, 2025
Revenue $27.5m $106m
Revenue growth 195.7% 38.9%
Net income −$26.6m −$81.1m
Operating margin — -87.3%
Net margin -96.9% -76.6%
Return on equity -121.1% -26.7%
Free cash flow −$21.9m −$34.5m
Cash $27.1m $41.2m
Total debt — $0
Debt to equity — 0.0%
Dividend per share — —
Dividend yield — —
Share buybacks — $41.7m
Employees 29 264
Market value $106m $2.16bn
Price vs our value range — —
Moat score 8 (Weak) —
Insider trades, 12 months 5 buys, 15 sales 0 buys, 11 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

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Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.