undamentalytics Newsletter

Cue Biopharma vs Lexicon Pharmaceuticals

Lexicon Pharmaceuticals is the larger business, with $49.8m of revenue in fiscal 2025 against $27.5m for Cue Biopharma (1.8 times as much). Cue Biopharma grew faster (195.7% against 60.2%). Cue Biopharma kept more of each dollar of sales as profit: a net margin of -96.9% against -101.1%.

Latest fiscal yearCue BiopharmaCUE, 2025Lexicon PharmaceuticalsLXRX, 2025
Revenue $27.5m $49.8m
Revenue growth 195.7% 60.2%
Net income −$26.6m −$50.3m
Operating margin — -98.2%
Net margin -96.9% -101.1%
Return on equity -121.1% -39.7%
Free cash flow −$21.9m −$67.9m
Cash $27.1m $34.3m
Total debt — $54.0m
Debt to equity — 50.2%
Dividend per share — —
Dividend yield — —
Share buybacks — —
Employees 29 —
Market value $106m $652m
Price vs our value range — —
Moat score 8 (Weak) 26 (Weak)
Insider trades, 12 months 5 buys, 15 sales 8 buys, 0 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

Go deeper

Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.