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Ensysce Biosciences vs Entrada Therapeutics

Entrada Therapeutics is the larger business, with $25.4m of revenue in fiscal 2025 against $5.1m for Ensysce Biosciences (5.0 times as much). Ensysce Biosciences grew faster (-2.8% against -87.9%). Ensysce Biosciences kept more of each dollar of sales as profit: a net margin of -200.8% against -565.5%. Entrada Therapeutics carries less debt relative to equity (0.0% against 9.5%).

Latest fiscal yearEnsysce BiosciencesENSC, 2025Entrada TherapeuticsTRDA, 2025
Revenue $5.1m $25.4m
Revenue growth -2.8% -87.9%
Net income −$10.2m −$144m
Operating margin -202.1% -621.1%
Net margin -200.8% -565.5%
Return on equity — -39.1%
Free cash flow −$7.9m −$130m
Cash $4.3m $90.4m
Total debt $306,708 $0
Debt to equity 9.5% 0.0%
Dividend per share — —
Dividend yield — —
Share buybacks — —
Employees — 152
Market value $5.9m $185m
Price vs our value range — —
Moat score — —
Insider trades, 12 months 2 buys, 0 sales 17 buys, 44 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

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Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.