Alector, Inc. key statistics and ratios

In fiscal 2025, Alector, Inc. had return on equity of -181.6%, an operating margin of -741.3%, debt equal to 33.8% of equity and a current ratio of 3.83. Each ratio below is calculated from the figures on its income statement, balance sheet and cash flow pages.

Financial ratios

US$ thousands unless shown otherwise. Fiscal years, plus the last twelve months (LTM) when newer.

Alector, Inc.: financial ratios, annual
Fiscal year	2017Dec 2017	2018Dec 2018	2019Dec 2019	2020Dec 2020	2021Dec 2021	2022Dec 2022	2023Dec 2023	2024Dec 2024	2025Dec 2025	LTMJun 2026
Operating margin	−874.9%	−207.0%	−539.2%	−925.1%	−18.0%	−103.2%	−156.3%	−144.2%	−741.3%	−912.4%
Net margin	−869.6%	−188.8%	−496.7%	−901.6%	−17.5%	−99.8%	−134.3%	−118.4%	−679.2%	−850.1%
Free-cash-flow margin	−497.2%	453.7%	−540.0%	−814.1%	142.6%	−18.3%	−192.1%	−229.9%	−874.7%	<−999%
Return on equity	—	—	—	−82.3%	−12.8%	−51.8%	−74.8%	−91.2%	−181.6%	—
Return on assets	—	−16.9%	−28.9%	−41.8%	−5.6%	−16.6%	−18.5%	−21.8%	−37.5%	−47.5%
Asset turnover	—	0.09	0.06	0.05	0.32	0.17	0.14	0.18	0.06	0.06
Current ratio	—	6.11	5.77	6.19	5.37	7.74	3.18	3.40	3.83	5.26
Debt to equity	—	—	0.0%	0.0%	0.0%	0.0%	0.0%	7.9%	33.8%	—
R&D as % of revenue	800.8%	263.9%	473.8%	743.5%	91.5%	157.5%	197.9%	184.9%	584.8%	715.1%
Capital spending as % of revenue	21.4%	6.8%	71.9%	23.9%	1.6%	3.1%	2.5%	1.2%	0.2%	1.2%

US$ thousands unless shown otherwise. Fiscal quarters.

Alector, Inc.: financial ratios, quarterly
Quarter	2024 Q3Sept 2024	2024 Q4Dec 2024	2025 Q1Mar 2025	2025 Q2Jun 2025	2025 Q3Sept 2025	2025 Q4Dec 2025	2026 Q1Mar 2026	2026 Q2Jun 2026
Operating margin	−315.7%	−13.4%	<−999%	−433.6%	<−999%	−634.4%	<−999%	−734.7%
Net margin	−275.2%	−3.8%	<−999%	−387.7%	<−999%	−597.5%	<−999%	−692.5%
Free-cash-flow margin	−332.1%	−101.8%	<−999%	−623.0%	−997.6%	−668.4%	<−999%	<−999%
Current ratio	3.29	3.40	3.34	3.78	3.76	3.83	5.25	5.26
Debt to equity	—	7.4%	10.0%	13.4%	16.7%	31.6%	94.1%	—
R&D as % of revenue	312.9%	85.7%	909.2%	350.7%	900.3%	520.5%	>999%	586.1%

Returns use average equity or assets over the year. Return on equity is left blank when equity is negative or so small that the ratio says nothing (above ±200%); interest cover is left blank above 200 times. Price-based ratios such as P/E are on the valuation page.

Financial health

4 of 5 checks passed · June 30, 2026

What it owns · $203m

Short-term assets $180mLonger-term assets $23m

What it owes, and who funded it · $213m

Short-term liabilities $34mLonger-term liabilities $179mShareholders' equity $-10m

Short-term assets cover short-term liabilities $180m of assets due within a year against $34m of liabilities due within a year.
Short-term assets cover long-term liabilities $180m short-term assets against $179m of longer-dated liabilities.
More cash than debt $60m of cash against $10m of debt.
Debt below 40% of shareholders' equity Equity or debt not reported. Not assessable.
Debt burden no higher than five years ago Five-year comparison not available. Not assessable.
A year's operating cash flow covers at least 20% of debt −$158m of operating cash flow against $10m of debt.
Operating profit covers interest at least five times over No material interest expense reported.

From Alector, Inc.'s latest balance sheet as filed. Checks are fixed, documented rules (methodology), counted only where the company reports the figures — a dot means the filing doesn't break the item out. Descriptions of reported data, not advice.

Moat

9 /100

Weak moat

How hard Alector's competitive advantage looks for rivals to wear away, judged from 8 years of its own filings: returns on capital, pricing power, profit durability, cash conversion and discipline.

Returns on capital 0 / 20

Net income has been a median -27.0% of total assets over 8 years.
Durability 10 / 20

Operating margin has been a median -318.0%; its worst year was -1000.5%.
Cash conversion 1 / 20

Free cash flow was positive in 1 of 8 years, at a median -363.0% of revenue.
Discipline 0 / 20

The diluted share count rose 36.9% over five years; stock-based pay has been a median 59.1% of revenue.

AI disruption exposure: Medium. In this industry, AI could change how the product is made or sold, without replacing the core asset. The score above includes a 5-point deduction for that exposure (14 before it).

A rules-based reading of reported figures, not a forecast and not investment advice. How the score is built: methodology.

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Figures from Alector, Inc.'s SEC filings (10-K and 10-Q), retrieved October 29, 2026. How we read and check them: methodology and data sources. Not investment advice. Back to Alector, Inc.