Humacyte, Inc. is a US-listed company in the biotechnology industry. Its financial year ends in December.
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~$0.4
Valuation models combined (2)
Base case. Range ~$0.2–$0.5. Weighted average of 2 models (growth cash-flow model, forward price-to-sales vs peers), the growth cash-flow model counting double.
No Buy/Hold/Sell rating is issued: limited reported history: available models are shown without a Buy/Hold/Sell rating.
Humacyte, Inc. valuation: adjust assumptions and compare models →
What company insiders, investment funds and members of Congress have been doing with the stock, from their own filings.
Humacyte has little or no product revenue yet; it used $98m of cash in the twelve months to June 2026. The diluted share count is up 45.7% on a year earlier, which dilutes existing holders. Our valuation models combined value is $0.57 a share, against a share price of $0.49.
Source: 10-Q filed August 12, 2026 on SEC EDGAR · Financials · Valuation
Humacyte has little or no product revenue yet; it used $98m of cash in the twelve months. The diluted share count is up 45.7% on a year earlier, which dilutes existing holders. It passes 3 of our 7 financial-health checks.
Written from the company's filings and our models when each quarter's report arrives. Figures in older notes are as published at the time. Not investment advice.
Humacyte, Inc.'s trailing-twelve-month revenue grew 159.3% year on year, with a free-cash-flow margin of -4599.7%.
Current signal Revenue growth decelerating: TTM revenue growth slowed to 159.3% (-130.7pp vs the prior quarter).
Assembled from SEC-filed figures — the full workings are on this page and in our methodology. Observations, not recommendations.
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Third-party market data · may be delayed
Company announcements, filed results and changes that matter to shareholders.
We value Humacyte, Inc. as an operating company, with every model that fits that kind of business. Cost of equity 12.5%: the 10-year Treasury yield (4.9%) plus a beta of 1.68 times a 4.5% equity risk premium.
| Model | Value per share | In the combined value? |
|---|---|---|
| Growth cash-flow model Revenue for this year and next from analysts' consensus, then growth fading to 2.5%; the operating margin moving to profitable peers'; investment needed per dollar of growth from peers; reduced by a failure probability. For young or fast-growing companies. The starting margin is normalized to between -100% and 60%; net margin is a proxy when operating income is not tagged. Uses analysts' consensus estimates (third-party data), not our forecasts. | ~$0.5 ~$0.3–$0.7 | Primary model, counts double |
| Price-to-earnings vs peers Earnings per share times peers' typical (harmonic-mean) price-to-earnings. | — | Does not apply: no positive earnings in the latest twelve months |
| Residual income Book value plus the present value of returns above the cost of equity, fading over ten years. | — | Does not apply: the model gives no positive value |
| Justified price-to-book Book value times (return on equity - growth) / (cost of equity - growth): steady-state returns. | — | Does not apply: return on equity is not positive |
| Forward price-to-sales vs peers Next year's consensus sales per share times peers' typical forward price-to-sales; only when earnings are negative. Uses analysts' consensus estimates (third-party data), not our forecasts. | ~$0.2 ~$0.3–$0.9 | Included, half weight |
| Revenue-to-maturity model Revenue grown to maturity with the cash margin moving to the industry's; for companies not yet profitable. | — | Does not apply: revenue and margins don't support a positive value |
| Combined value Weighted average of the models that apply: the primary model (growth cash-flow model) counts double. Models more than 5x or less than 0.2x the share price, or more than 3x away from the other models' median, are left out. | ~$0.4 ~$0.2–$0.5 | 2 models |
Different models fail in different ways, so where several apply we average them rather than trust one. Peer-based models compare Humacyte, Inc. with Biotechnology in our coverage, using third-party market data. Model values are estimates under stated assumptions, updated as new filings arrive; not price targets or investment advice. How each model works.
| At fiscal year end | 2024 | 2025 | Now |
|---|---|---|---|
| Share price | $5.05 | $0.96 | $0.40 |
| Market value | $598m | $152m | $77m |
| + Net debt (− = net cash) | $18m | −$15m | −$44m |
| Enterprise value | $617m | $137m | $34m |
| Multiples | |||
| Price / sales | — | 74.6x | 36.5x |
| Price / earnings | — | — | — |
| Price / free cash flow | — | — | — |
| EV / EBITDA | — | — | — |
Not assessed: fewer than five years of comparable figures in the filings. AI disruption exposure for this industry: Medium.
Next results: November 12, 2026, before the open. Analysts expect revenue of $770000 and EPS of −$0.08 (range −$0.10 to −$0.06) for the quarter.
| Fiscal year | EPS | Growth | Revenue | Growth |
|---|---|---|---|---|
| Current | −$0.40 | −54% | $4m | +72% |
| Next | −$0.25 | +38% | $22m | +519% |
The consensus EPS forecast for the current fiscal year is +14.3% on 90 days ago. In the last 30 days, 1 analyst raised Humacyte, Inc.'s forecast and 2 cut it.
Average of analysts' published estimates (third-party data).
| Period | Current fiscal year | Next fiscal year |
|---|---|---|
| 90 days ago | −$0.35 | −$0.24 |
| 60 days ago | −$0.40 | −$0.25 |
| 30 days ago | −$0.40 | −$0.25 |
| 7 days ago | −$0.40 | −$0.25 |
| Now | −$0.40 | −$0.25 |
| Quarter to | Estimate | Actual | Surprise |
|---|---|---|---|
| Jun 2026 | −$0.10 | −$0.16 | −54.8% |
| Mar 2026 | −$0.12 | −$0.09 | +21.7% |
| Dec 2025 | −$0.14 | −$0.13 | +3.7% |
| Sept 2025 | −$0.15 | −$0.11 | +25.8% |
Adjusted EPS as companies report it, against the average analyst estimate.
Last 12 months −76.2%
| Part | Then | Now | Effect |
|---|---|---|---|
| Revenue (last 12 months) | $818000 | $2m | +159.3% |
| P/S multiple | n/m | 36.5x | −86.6% |
| Share count | 133m | 194m | −31.4% |
Biggest factor: p/s multiple. Loss-making at one end, so the split uses price/sales.
| Calendar year | 2021 | 2022 | 2023 | 2024 | 2025 | 2026 to date |
|---|---|---|---|---|---|---|
| Return | ||||||
| HUMA | −29% | −71% | +35% | +78% | −81% | −59% |
| Industry peers (median) | −36% | −56% | −18% | −29% | −5% | −26% |
| S&P 500 | +29% | −18% | +26% | +25% | +18% | +11% |
| Months that ended higher | ||||||
| HUMA | 33% | 50% | 75% | 50% | 25% | 36% |
| S&P 500 | 75% | 42% | 67% | 75% | 75% | 46% |
| Largest fall from a high during the year | ||||||
| HUMA | −57% | −74% | −60% | −63% | −81% | −76% |
| S&P 500 | −5% | −25% | −10% | −8% | −19% | −9% |
Worst fall since December 1, 2020: 98% from September 1, 2021 to October 14, 2026. Getting back needed a 4699% gain, and the shares have not yet recovered.
| Results released | Next day | S&P 500 next day | 5 days | 21 days |
|---|---|---|---|---|
| August 12, 2026 | −22.5% | +0.9% | +3.5% | −20.0% |
| March 19, 2026 | −26.1% | −1.7% | −26.6% | −35.1% |
| November 12, 2025 | −7.0% | −1.6% | −8.6% | +2.3% |
| August 11, 2025 | −27.6% | +0.9% | −27.4% | −40.3% |
| May 13, 2025 | +41.7% | +0.8% | +88.6% | +82.6% |
| March 28, 2025 | −15.2% | −1.4% | −32.8% | −28.9% |
| November 8, 2024 | +4.9% | +0.5% | −8.1% | −19.0% |
| August 13, 2024 | −9.1% | +2.0% | −5.5% | −15.0% |
| May 10, 2024 | +21.2% | +0.1% | +40.0% | +54.6% |
| March 22, 2024 | −12.8% | −0.5% | −16.4% | +9.2% |
| November 9, 2023 | +7.3% | +0.8% | +11.4% | +25.1% |
| August 14, 2023 | +37.0% | −0.6% | +3.1% | +19.0% |
Source: SEC EDGAR filings. Retrieved October 29, 2026.
| Period | Revenue (TTM) |
|---|---|
| FY24 Q4 | $0 |
| FY25 Q1 | $517K |
| FY25 Q2 | $818K |
| FY25 Q3 | $1.6M |
| FY25 Q4 | $2M |
| FY26 Q1 | $2M |
| FY26 Q2 | $2.1M |
Source: SEC EDGAR filings. Retrieved October 29, 2026.
| Period | Operating margin (TTM) |
|---|---|
| FY25 Q1 | -21470.8% |
| FY25 Q2 | -13598.0% |
| FY25 Q3 | -6708.4% |
| FY25 Q4 | -5306.0% |
| FY26 Q1 | -5649.2% |
| FY26 Q2 | -5240.8% |
Source: SEC EDGAR filings. Retrieved October 29, 2026.
| Period | FCF margin (TTM) |
|---|---|
| FY25 Q1 | -19494.2% |
| FY25 Q2 | -12994.0% |
| FY25 Q3 | -6772.9% |
| FY25 Q4 | -5197.5% |
| FY26 Q1 | -5078.2% |
| FY26 Q2 | -4599.7% |
| Fiscal year | 2024 Dec 2024 | 2025 Dec 2025 | LTM Jun 2026 |
|---|---|---|---|
| Income | |||
| Revenue | 0 | 2 | 2 |
| Gross profit | 0 | −8 | −10 |
| EBITDA | −109 | −103 | −106 |
| Operating income | −114 | −108 | −111 |
| Net income | −149 | −41 | −97 |
| Diluted EPS | −$1.26 | −$0.26 | −$0.50 |
| Growth (year on year) | |||
| Revenue | — | — | +159.3% |
| Margins | |||
| Gross margin | — | −376.1% | −494.6% |
| EBITDA margin | — | <−999% | <−999% |
| Operating margin | — | <−999% | <−999% |
| Net margin | — | <−999% | <−999% |
| Free-cash-flow margin | — | <−999% | <−999% |
| Cash flow | |||
| Cash from operations | −98 | −105 | −97 |
| Capital spending | 2 | 1 | 0 |
| Free cash flow | −100 | −106 | −98 |
| Stock-based pay | 6 | 10 | 11 |
| Free cash flow after stock pay | −106 | −116 | −108 |
| Balance sheet | |||
| Cash | 45 | 50 | 80 |
| Total debt | 63 | 35 | 36 |
| Net debt (negative = net cash) | 18 | −15 | −44 |
| Diluted shares | 118m | 158m | 194m |
| Quarter | 2024 Q3 Sept 2024 | 2024 Q4 Dec 2024 | 2025 Q1 Mar 2025 | 2025 Q2 Jun 2025 | 2025 Q3 Sept 2025 | 2025 Q4 Dec 2025 | 2026 Q1 Mar 2026 | 2026 Q2 Jun 2026 |
|---|---|---|---|---|---|---|---|---|
| Income | ||||||||
| Revenue | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
| Gross profit | 0 | 0 | 0 | 0 | 0 | −9 | −2 | −1 |
| EBITDA | −29 | −27 | −22 | −28 | −23 | −29 | −28 | −26 |
| Operating income | −30 | −28 | −23 | −30 | −24 | −31 | −29 | −27 |
| Net income | −39 | −21 | 39 | −38 | −18 | −25 | −18 | −37 |
| Diluted EPS | −$0.33 | −$0.16 | $0.28 | −$0.24 | −$0.11 | −$0.15 | −$0.09 | −$0.16 |
| Growth (year on year) | ||||||||
| Revenue | — | — | — | — | — | — | −4.3% | +34.9% |
| Net income | — | — | — | — | — | — | −145.0% | — |
| Diluted EPS | — | — | — | — | — | — | −132.1% | — |
| Margins | ||||||||
| Gross margin | — | — | 71.6% | 29.2% | 65.5% | <−999% | −311.7% | −203.2% |
| EBITDA margin | — | — | <−999% | <−999% | <−999% | <−999% | <−999% | <−999% |
| Operating margin | — | — | <−999% | <−999% | <−999% | <−999% | <−999% | <−999% |
| Net margin | — | — | >999% | <−999% | <−999% | <−999% | <−999% | <−999% |
| Free-cash-flow margin | — | — | <−999% | <−999% | <−999% | <−999% | <−999% | <−999% |
| Cash flow | ||||||||
| Cash from operations | −23 | −27 | −29 | −26 | −24 | −26 | −25 | −22 |
| Capital spending | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| Free cash flow | −24 | −27 | −29 | −27 | −24 | −26 | −25 | −22 |
| Stock-based pay | 2 | 2 | 2 | 2 | 3 | 2 | 3 | 3 |
| Free cash flow after stock pay | −25 | −28 | −31 | −29 | −26 | −29 | −28 | −25 |
| Last 12 months unless stated | HUMA | KRSA | CLGN | KRRO | MCRB | VTGN | Median |
|---|---|---|---|---|---|---|---|
| Revenue, last 12 months | $2m | $2m | $2m | $2m | $2m | $3m | $55m |
| Revenue growth, last 12 months | 159.3% | −12.6% | 360.4% | −62.1% | 100.0% | 287.3% | 12.7% |
| Revenue growth, 3-year average | — | — | — | −53.7% | −75.6% | — | 13.7% |
| Revenue growth, latest quarter | 34.9% | −100.0% | — | −100.0% | 100.0% | 504.9% | 10.2% |
| Gross margin | −494.6% | — | 64.8% | — | — | — | 82.8% |
| Operating margin | <−999% | −359.2% | −484.3% | <−999% | <−999% | <−999% | −191.1% |
| Operating margin, 3-year average | — | <−999% | — | <−999% | <−999% | <−999% | −363.5% |
| Net margin | <−999% | −353.0% | −484.6% | <−999% | <−999% | <−999% | −172.8% |
| Cash from operations / revenue | <−999% | −234.3% | −397.3% | <−999% | <−999% | <−999% | −168.8% |
| Free-cash-flow margin | <−999% | <−999% | −398.4% | <−999% | <−999% | <−999% | −168.1% |
| Free-cash-flow margin, 3-year average | — | — | — | <−999% | −900.2% | <−999% | −310.0% |
| Stock pay / revenue | 507.2% | 16.9% | 42.1% | 391.7% | 487.8% | 162.7% | 20.7% |
| Change in share count | 45.7% | 45.4% | 6.5% | 28.2% | 11.0% | 30.8% | 8.3% |
| Line of business | Revenue | Share | YoY |
|---|---|---|---|
| Products | $1.4M | 68.2% | — |
| Other | $649,000 | 31.8% | — |
From Humacyte, Inc.'s 10-K filed March 27, 2026, as tagged in the filing. View filing. Indented rows are part of the line above; their share is of that line. In the bars, the faint bar behind is the year before.
| Manager | Value | Shares | Share of 13F value | Shares QoQ |
|---|---|---|---|---|
| Antipodes Partners Ltd | $7.9M | 10.1M | 13.8% | ▲ 76.5% |
| Vanguard Capital Management LLC | $7.9M | 10.1M | 13.8% | ▲ 41.2% |
| Alyeska Investment Group, L.P. | $4.7M | 6.0M | 8.2% | New |
| Davidson Kempner Capital Management LP | $3.9M | 5.0M | 6.8% | — |
| Blackrock, Inc. | $3.8M | 4.8M | 6.6% | ▼ 60.7% |
| Great Point Partners LLC | $2.9M | 3.8M | 5.1% | 0.0% |
| UBS Group AG | $2.2M | 2.8M | 3.9% | ▲ 2.2% |
| AQR Capital Management LLC | $2M | 2.6M | 3.5% | ▲ 34.9% |
| Geode Capital Management, LLC | $1.7M | 2.2M | 3.0% | ▼ 40.3% |
| Millennium Management LLC | $1.5M | 1.9M | 2.6% | ▲ 1665.1% |
| Susquehanna International Group, LLP | $1.3M | 1.7M | 2.3% | ▲ 60.6% |
| Citadel Advisors LLC | $1.1M | 1.4M | 2.0% | New |
From Form 13F filings with the SEC ( quarterly data sets), as reported by each manager for June 30, 2026 and filed up to 45 days later. 13F reports cover long US-listed positions of managers above $100M only, so this is not Humacyte, Inc.'s complete shareholder register. Values are as reported by the filers .
| Insider | Date | Trade | Shares | Price | Value |
|---|---|---|---|---|---|
| Jones Keith Anthony Director | September 14, 2026 | Buy | 10,000 | $0.56 | $5,600 |
| Jones Keith Anthony Director | August 20, 2026 | Buy | 10,000 | $0.69 | $6,900 |
| Jones Keith Anthony Director | August 17, 2026 | Buy | 30,000 | $0.59 | $17,700 |
| Sebelius Kathleen Director | May 19, 2026 | Buy | 56,818 | $0.88 | $50,000 |
| Parikh Shamik J Chief Medical Officer | May 18, 2026 | Sell pre-set plan | 45,887 | $0.90 | $41,298 |
| Sander Dale A. CFO and Chief Corp. Dev. Off | May 18, 2026 | Sell pre-set plan | 45,887 | $0.90 | $41,298 |
| Constantino Michael T. Director | May 18, 2026 | Buy | 11,000 | $0.89 | $9,790 |
From insiders' Form 4 filings with the SEC. Excludes awards, option exercises and shares withheld for tax. "Pre-set plan" means the filing marks the trade as made under a Rule 10b5-1 plan. See every insider trade since five years ago, on a price chart.
Next expected around November 16, 2026 estimated from the company's past filing pattern, not announced
| Data | Last updated | Source |
|---|---|---|
| Share price | Exchange closing prices | |
| Financial statements | SEC 10-K and 10-Q filings | |
| News and updates | Company releases and SEC 8-K filings | |
| Analyst estimates | Aggregated analyst estimates | |
| Valuation and scores | Our models, from the filed figures |
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