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Sera Prognostics, Inc. key statistics and ratios

In fiscal 2025, Sera Prognostics, Inc. had return on equity of -51.8%, an operating margin of -45066.7%, debt equal to 0.0% of equity and a current ratio of 1.69. Each ratio below is calculated from the figures on its income statement, balance sheet and cash flow pages.

Financial ratios

US$ thousands unless shown otherwise. Fiscal years, plus the last twelve months (LTM) when newer.

Sera Prognostics, Inc.: financial ratios, annual
Fiscal year2020Dec 20202021Dec 20212022Dec 20222023Dec 20232024Dec 20242025Dec 2025LTMJun 2026
Gross margin———31.4%−6.5%——
Operating margin<−999%<−999%<−999%<−999%<−999%<−999%<−999%
Net margin<−999%<−999%<−999%<−999%<−999%<−999%<−999%
Free-cash-flow margin<−999%<−999%<−999%<−999%<−999%<−999%<−999%
Return on equity——−37.2%−42.9%−55.8%−51.8%−49.3%
Return on assets−134.1%−43.3%−33.6%−34.2%−39.2%−36.6%−35.2%
Asset turnover0.000.000.000.000.000.000.00
Current ratio1.2213.115.802.511.921.691.98
Debt to equity—0.0%0.0%0.0%0.0%0.0%0.0%
Interest cover (operating income ÷ interest)———n/mn/mn/mn/m
R&D as % of revenue>999%>999%>999%>999%>999%>999%>999%
Capital spending as % of revenue596.0%>999%295.1%41.8%72.7%896.3%665.7%

Returns use average equity or assets over the year. Return on equity is left blank when equity is negative or so small that the ratio says nothing (above ±200%); interest cover is left blank above 200 times. Price-based ratios such as P/E are on the valuation page.

Financial health

2 of 3 checks passed · June 30, 2026
What it owns · $87m
Short-term assets $48mLonger-term assets $39m
What it owes, and who funded it · $87m
Short-term liabilities $24mLonger-term liabilities $3mShareholders' equity $59m
  • Short-term assets cover short-term liabilities $48m of assets due within a year against $24m of liabilities due within a year.
  • Short-term assets cover long-term liabilities $48m short-term assets against $3m of longer-dated liabilities.
  • More cash than debt Cash or debt not separately reported. Not assessable.
  • Debt below 40% of shareholders' equity Equity or debt not reported. Not assessable.
  • Debt burden no higher than five years ago Five-year comparison not available. Not assessable.
  • A year's operating cash flow covers at least 20% of debt Cash flow or debt not reported. Not assessable.
  • Operating profit covers interest at least five times over Operating income of −$37m against $7,000 of interest.

From Sera Prognostics, Inc.'s latest balance sheet as filed. Checks are fixed, documented rules (methodology), counted only where the company reports the figures — a dot means the filing doesn't break the item out. Descriptions of reported data, not advice.

Moat

12 /100

Weak moat

How hard Sera Prognostics's competitive advantage looks for rivals to wear away, judged from 6 years of its own filings: returns on capital, pricing power, profit durability, cash conversion and discipline.

  • Returns on capital 0 / 20

    Net income has been a median -37.0% of total assets over 6 years.

  • Durability 10 / 20

    Operating margin has been a median -33596.1%; its worst year was -53282.9%.

  • Cash conversion 0 / 20

    Free cash flow was positive in 0 of 6 years, at a median -23965.0% of revenue.

AI disruption exposure: Medium. In this industry, AI could change how the product is made or sold, without replacing the core asset. The score above includes a 5-point deduction for that exposure (17 before it).

A rules-based reading of reported figures, not a forecast and not investment advice. How the score is built: methodology.

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Figures from Sera Prognostics, Inc.'s SEC filings (10-K and 10-Q), retrieved October 29, 2026. How we read and check them: methodology and data sources. Not investment advice. Back to Sera Prognostics, Inc.