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Lexicon Pharmaceuticals vs Sutro Biopharma

Sutro Biopharma is the larger business, with $102m of revenue in fiscal 2025 against $49.8m for Lexicon Pharmaceuticals (2.1 times as much). Sutro Biopharma grew faster (65.2% against 60.2%). Lexicon Pharmaceuticals kept more of each dollar of sales as profit: a net margin of -101.1% against -186.5%.

Latest fiscal yearLexicon PharmaceuticalsLXRX, 2025Sutro BiopharmaSTRO, 2025
Revenue $49.8m $102m
Revenue growth 60.2% 65.2%
Net income −$50.3m −$191m
Operating margin -98.2% —
Net margin -101.1% -186.5%
Return on equity -39.7% —
Free cash flow −$67.9m −$177m
Cash $34.3m $58.1m
Total debt $54.0m $0
Debt to equity 50.2% —
Dividend per share — —
Dividend yield — —
Share buybacks — —
Employees — 137
Market value $643m $151m
Price vs our value range — —
Moat score 26 (Weak) 14 (Weak)
Insider trades, 12 months 8 buys, 0 sales 0 buys, 0 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

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Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.